Institute for Translational Medicine

The Department

The history of the Department of Pathophysiology in Pécs is closely linked to the name of professor Szilárd Donhoffer (1902-1999). He was the founder of the Department: he started his career as a physician in the Clinic of Internal Medicine under the supervision of professor János Ángyán. As an outstanding physician and researcher he was appointed as head of the newly established Department of Pathophysiology in 1949. He was the author the first (single-author) textbook of Pathophysiology that was famous for being extremely difficult and also for requiring rational analytical thinking (1957, 1961). 1964-67 he served as rector of the University, from 1964 he was elected member of the Hungarian Academy of Sciences. With his keen intellect professzor Donhoffer followed the research and teaching activity of his Department until his very death.

 

 

 

Contacts

Institute Director: Prof. Dr. Hegyi Péter
Address: 7624 Pécs, Szigeti út 12. 2nd floor
Mailing address: 7601 Pécs, Pf.: 99
Phone: +36-72-536-246
Fax: +36-72-536-247
E-mail:

Each year, the Medical School recognizes 3 departments and 3 clinics, the best lecturers of theoretical and clinical subjects as well as excellent practice instructors based on the votes of graduating students.

Each year the Dean and the Director of the Clinical Centre recognize the performance of 3 theoretical and 3 clinical departments with the Excellent Department/Excellent Clinic award.

Research and Thesis Topics for Students

 

Senile sarcopenia: development and complications. (experimental)

Tutor: dr. Miklós Székely

 

The healthcare-related aspects of global climatic changes. (theoretical)

Tutor: dr. Miklós Székely

 

Age-related changes in peptidergic regulaton of energy balance. (experimental)

Tutors: dr. Miklós Székely, dr. Márta Balaskó

 

Obesity: insulin and other peptides in body weight regulation. (experimental/theoretical)

Tutors: dr. Miklós Székely, dr. Erika Pétervári

 

Melanocortins in the regulation of food intake and body temperature. (experimental)

Tutors: dr. Miklós Székely, dr. Erika Pétervári

 

Abdominal vagal afferentation in energy homeostasis. (experimental)

Tutors: dr. Miklós Székely, dr. Margit Solymár, dr. Garami András

 

Xenoestrogens and other endocrine disruptors in select disease processes. (literature oriented)

Tutor: dr. János Garai

 

Endocrinology of catechol-oestrogens. (literature oriented)

Tutor: dr. János Garai

 

Inflammatory mechanisms in estrogen’s hormonal effect. (literature oriented)

Tutor: dr. János Garai

 

Enzymatic activity of the macrophage migration inhibitory factor (MIF). (experimental & literature oriented)

Tutor: dr. János Garai

 

Phytoestrogens’ effectivity in menopause. (clinical/experimental & literature oriented)

Tutors: dr. János Garai, dr. József Bódis (Department of Obstetrics and Gynaecology)

 

Inflammatory mediators in the pathomechanism of endometriosis (clinical/experimental & literature oriented)

Tutors: dr. János Garai, dr. József Bódis (Department of Obstetrics and Gynaecology)

 

The role of corticotropin-releasing hormone receptor (CRH) and urocortins in energy homeostasis. (experimental)

Tutor: dr. Márta Balaskó

 

Cholecystokinin and energy homeostasis. (experimental)

Tutor: dr. Márta Balaskó

 

The effects of perinatal (maternal and foetal) nutritional state on the postnatal development of body weight, body composition and on the potential development of obesity. (experimental)

Tutors: dr. Márta Balaskó, dr. Erika Pétervári, dr. Szilvia Soós

 

 

The role of leptin in energy balance: age- and nutritional state-related alterations. (experimental)

 

Tutor: dr. Erika Pétervári

 

The role of neuropeptide Y (NPY) in energy balance: age- and nutritional state-related alterations. (experimental)

Tutor: dr. Erika Pétervári

 

Circadian changes in core temperature and spontaneous activity of rodents: age- and nutritional state-related alterations. Biotelemetric studies. (experimental)

Tutors: dr. Erika Pétervári, dr. Margit Solymár

 

The central regulatory role of insulin in energy balance: age- and nutritional state-related alterations. (experimental)

Tutor: dr. Szilvia Soós

 

A hot topic for feverish student research: the (patho)physiology of TRPV1. (theoretical/experimental)

Tutor: dr. András Garami

The role of neurokinin-1 (NK1) receptor in processes of energy balance. (theoretical/experimental)
Tutor: dr. Andras Garami