The various Gram-positive and Gram-negative multiresistant pathogens present a serious clinical and public hygienic problem worldwide. The aims of our investigations are to identify the genes responsible for resistance, estimate their occurrence and reveal their ways of spreading in multiresistant pathogens originating from the hospitals of Clinical Centre University of Pécs. With the help of the information obtained from these studies we would like to facilitate the early detection of emerging multiresistant pathogens, enhance the efficiency of infection control policies and contribute to the development of local antimicrobial protocols. Students will be able to gain experience in various methods of molecular biology. Besides they will have the opportunity to familiarize themselves with traditional bacteriological procedures.