Student Researchers' Society Topics
Challenges of recanalisation therapy in acute stroke patients taking DOACs
Supervisor: SZAPÁRY, László
Direct oral anticoagulants (DOACs), such as apixaban, dabigatran, edoxaban and rivaroxaban, are the recommended primary therapy in preventing acute ischemic stroke (AIS) in patients with non-valvular atrial fibrillation. However, despite the high effectiveness of DOACs, an annual AIS risk of 1-2% endures. Intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are interventions capable of reducing AIS-related morbidity and augmenting the prospects of functional recovery. Nevertheless, DOAC intake within 48-hours preceding IVT is deemed as a (relative) contraindication due to the presumed heightened risk of symptomatic intracranial hemorrhage (sICH). Despite the strength of this recommendation, the current amount of evidence remains insufficient. Therefore this study investigates the cohort of affected patients otherwise eligible for IVT, aiming to determine whether the benefits of reperfusion therapy might outweigh the associated risk of hemorrhagic transformation.
Clinical diagnostics and myopathology of mitochondrial diseases
Supervisor: PÁL, Endre
The purpose of the study to classify and buid up a register for the mitochondrial patients diagnosed in the Neurology clinic. Furthemor, morphological analysis of the muscle biosy specimens.
Clinical, pathological and genetic diagnosis of myotonic dystrophy.
Supervisor: PÁL, Endre
During the study we analyze the clinical, genetic and muscle biopsy findings of patients with myotonic dystrophy.
Examination of various behavioural disorders in Parkinson's disease
Supervisor: KOVÁCS, Norbert
Examination of various behavioural disorders in Parkinson's disease
Multifocal motor neuropathy
Supervisor: PFUND, Zoltán
Aims: 1. Investigation of MMN patients, 2. Reading their medical records, 3. Making a patient's database (e.g., age, gender, disease onset, disease duration, impaired nerve at onset, progression of nerve involvents, effectiveness of IVIg), 4. Overview of MMN literature, 5. Writing of the thesis.
Neurosurgical treatment of movement disorders (Parkinson’s disease, tremor and dystonia)
Supervisor: KOVÁCS, Norbert
In this topic the students can learn and analyse the results of the technique of deep brain stimulation, intraoperative electophysiology and patient programming. Both clinical research or literature review are available.
Pharmacological treatment of Parkinson’s disease
Supervisor: KOVÁCS, Norbert
In this topic the students can learn about the pharmacological treatment of Parkinson’s disease and the examination of patients. Both clinical research or literature review are available.
The role of repetitive transcranial magnetic stimulation in the clinical practice
Supervisor: KOVÁCS, Norbert
The role of repetitive transcranial magnetic stimulation in the clinical practice