cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation
Transcription is globally repressed in early stage of embryo development, but a set of genes including pri-miR-430 and zinc finger genes is known to escape the repression. Here the authors image the very first transcriptional activities in the living zebra fish embryo, demonstrating a cell cycle-coordinated polymerase II transcription compartment.
https://www.nature.com/articles/s41467-019-08487-5