Gyógyszerhatástani Tanszék

Az utóbbi öt év tudományos közleményei

 

2020

 

Zelma Faisal, Edina Garai, Rita Csepregi, Katalin Bakos, Eszter Fliszár-Nyúl, Lajos Szente, Adrienn Balázs, Mátyás Cserháti, Tamás Kőszegi, Béla Urbányi, Zsolt Csenki, Miklós Poór, Protective effects of beta-cyclodextrins vs. zearalenone-induced toxicity in HeLa cells and Tg(vtg1:mCherry) zebrafish embryos. Chemosphere 240 (2020) 124948. [IF: 5,108]

 

2019

 

Eszter Fliszár-Nyúl, Violetta Mohos, Tímea Bencsik, Beáta Lemli, Sándor Kunsági-Máté, Miklós Poór, Interactions of 7,8-dihydroxyflavone with serum albumin as well as with CYP2C9, CYP2C19, CYP3A4, and xanthine oxidase biotransformation enzymes. Biomolecules 9 (2019) 655. [IF: 4,694]


Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté, Lajos Szente, Miklós Poór, Interactions of mycotoxin alternariol with cyclodextrins and its removal from aqueous solution by beta-cyclodextrin bead polymer. Biomolecules 9 (2019) 428. [IF: 4,694]


Zelma Faisal, Eszter Fliszár-Nyúl, Luca Dellafiora, Gianni Galaverna, Chiara Dall’Asta, Beáta Lemli, Sándor Kunsági-Máté, Lajos Szente, Miklós Poór, Cyclodextrins can entrap zearalenone-14-glucoside: Interaction of the masked mycotoxin with cyclodextrins and cyclodextrin bead polymer. Biomolecules 9 (2019) 354. [IF: 4,694]

 

Zelma Faisal, Sándor Kunsági-Máté, Beáta Lemli, Lajos Szente, Dominik Bergmann, Hans-Ulrich Humpf, Miklós Poór, Interaction of dihydrocitrinone with native and chemically modified cyclodextrins. Molecules 24 (2019) 1328. [IF: 3,060]

 

Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté, Luca Dellafiora, Chiara Dall'Asta, Gabriele Cruciani, Gábor Pethő, Miklós Poór, Interaction of mycotoxin alternariol with serum albumin. International Journal of Molecular Sciences 20 (2019) 2352. [IF: 4,183]

 

Violetta Mohos, Attila Pánovics, Eszter Fliszár-Nyúl, Gabriella Schilli, Csaba Hetényi, Přemysl Mladěnka, Paul W. Needs, Paul A. Kroon, Gábor Pethő, Miklós Poór, Inhibitory effects of quercetin and its human and microbial metabolites on xanthine oxidase enzyme. International Journal of Molecular Sciences 20 (2019) 2681. [IF: 4,183]

 

Róbert György Vida, András Fittler, Anna Somogyi-Végh, Miklós Poór, Dietary quercetin supplements: assessment of online product informations and quantitation of quercetin in the products by high performance liquid chromatography. Phytotherapy Research (2019) doi: 10.1002/ptr.6382 [IF: 3,766]

 

Zelma Faisal, Virág Vörös, Beáta Lemli, Diána Derdák, Sándor Kunsági-Máté, Mónika Bálint, Csaba Hetényi, Rita Csepregi, Tamás Kőszegi, Dominik Bergmann, Franziska Sueck, Hans-Ulrich Humpf, Florian Hübner, Miklós Poór, Interaction of the mycotoxin metabolite dihydrocitrinone with serum albumin. Mycotoxin Research 35 (2019) 129-139. [IF: 3,741]

 

Diána Derdák, Miklós Poór, Sándor Kunsági-Máté, Beáta Lemli, Interaction of amphotericin B with human and bovine serum albumins: A fluorescence polarization study. Chemical Physics Letters 724 (2019) 13-17. [IF: 1,901]

 

Zsuzsanna Helyes, Valéria Tékus, Nikolett Szentes, Krisztina Pohóczky, Bálint Botz, Tamás Kiss, Ágnes Keménya, Zsuzsanna Környei, Krisztina Tóth, Nikolett Lénárt, Hajnalka Ábrahám, Emmanuel Pinteaux, Sheila Francis, Serena Sensi, Ádám Dénes, Andreas Goebel, Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin1–induced mechanisms. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019) doi: 10.1073/pnas.1820168116 [IF: 9,580]

 

Nikolett Szentes, Valéria Tékus, Violetta Mohos, Éva Borbély, Zsuzsanna Helyes, Exploratory and locomotor activity, learning and memory functions in somatostatin receptor subtype 4 gene-deficient mice in relation to aging and sex. Geroscience 116 (2019) 13067–13076. [IF: 6,444]

 

Eszter Ducza, Adrienn Csányi, Éva Szőke, Krisztina Pohóoczky, Judit Hajagos-Tóth, Anna Kothencz, Zita Tiszai, Róbert Gáspár, Significance of transient receptor potential vanilloid 4 and aquaporin 5 co-expression in the rat uterus at term. Heliyon 5 (2019) e02697.

 

2018

 

Nikolett Sali, Rita Csepregi, Tamás Kőszegi, Sándor Kunsági-Máté, Lajos Szente, Miklós Poór, Complex formation of flavonoids fisetin and geraldol with β-cyclodextrins. Journal of Luminescence 194 (2018) 82-90. [IF: 2,961]

 

Miklós Poór, Gabriella Boda, Sándor Kunsági-Máté, Paul W. Needs, Paul A. Kroon, Beáta Lemli, Fluorescence spectroscopic evaluation of the interactions of quercetin, isorhamnetin, and quercetin-3'-sulfate with different albumins. Journal of Luminescence 194 (2018) 156-163. [IF: 2,961]

 

Rita Csepregi, Beáta Lemli, Sándor Kunsági-Máté, Lajos Szente, Tamás Kőszegi, Balázs Németi, Miklós Poór, Complex formation of resorufin and resazurin with β-cyclodextrins: Can cyclodextrins interfere with a resazurin cell viability assay? Molecules 23 (2018) 382. [IF: 3,060]

 

Miklós Poór, Gabriella Boda, Violetta Mohos, Mónika Kuzma, Mónika Bálint, Csaba Hetényi, Tímea Bencsik, Pharmacokinetic interaction of diosmetin and silibinin with other drugs: Inhibition of CYP2C9-mediated biotransformation and displacement from serum albumin. Biomedicine & Pharmacotherapy 102 (2018) 912-921. [IF: 3,743]

 

Miklós Poór, Zelma Faisal, Afshin Zand, Tímea Bencsik, Beáta Lemli, Sándor Kunsági-Máté, Lajos Szente, Removal of zearalenone and zearalenols from aqueous solutions using insoluble beta-cyclodextrin bead polymer. Toxins 10 (2018) 216. [IF: 3,895]

 

Franziska Sueck, Miklós Poór, Zelma Faisal, Christoph G.W. Gertzen, Benedikt Cramer, Beáta Lemli, Sándor Kunsági-Máté, Holger Gohlke, Hans-Ulrich Humpf, Interaction of ochratoxin A and its thermal degradation product 2’R-ochratoxin A with human serum albumin. Toxins 10 (2018) 256. [IF: 3,895]

 

Rita Csepregi, Viktória Temesfői, Miklós Poór, Zsuzsanna Faust, Tamás Kőszegi, Green Fluorescent Protein-based viability assay in a multipara-metric configuration. Molecules 23 (2018) 1575. [IF: 3,060]

 

Zelma Faisal, Beáta Lemli, Dénes Szerencsés, Sándor Kunsági-Máté, Mónika Bálint, Csaba Hetényi, Mónika Kuzma, Mátyás Mayer, Miklós Poór, Interactions of zearalenone and its reduced metabolites α-zearalenol and β-zearalenol with serum albumins: species differences, binding sites, and thermodynamics. Mycotoxin Research 34 (2018) 269-278. [IF: 3,741]

 

Violetta Mohos, Tímea Bencsik, Gabriella Boda, Eszter Fliszár-Nyúl, Beáta Lemli, Sándor Kunsági-Máté, Miklós Poór, Interactions of casticin, ipriflavone, and resveratrol with serum albumin and their inhibitory effects on CYP2C9 and CYP3A4 enzymes. Biomedicine & Pharmacotherapy 107 (2018) 777-784. [IF: 3,743]

 

Zelma Faisal, Diána Derdák, Beáta Lemli, Sándor Kunsági-Máté, Mónika Bálint, Csaba Hetényi, Rita Csepregi, Tamás Kőszegi, Franziska Sueck, Hans-Ulrich Humpf, Benedikt Cramer, Miklós Poór, Interaction of 2'R-ochratoxin A with serum albumins: Binding site, effects of site markers, thermodynamics, species differences of albumin-binding, and influence of albumin on its toxicity in MDCK cells. Toxins 10 (2018) 353. [IF: 3,895]

 

Rita Csepregi, Viktória Temesfői, Nikolett Sali, Miklós Poór, Paul W. Needs, Paul A. Kroon, Tamás Kőszegi, A one-step extraction and luminescence assay for quantifying glucose and ATP levels in cultured HepG2 cells. International Journal of Molecular Sciences 19 (2018) 2670. [IF: 4,183]

 

Violetta Mohos, Eszter Fliszár-Nyúl, Gabriella Schilli, Csaba Hetényi, Beáta Lemli, Sándor Kunsági-Máté, Balázs Bognár, Miklós Poór, Interaction of chrysin and its main conjugated metabolites chrysin-7-sulfate and chrysin-7-glucuronide with serum albumin. International Journal of Molecular Sciences (2018) Accepted [IF: 4,183]

 

Gabriella Gulyas, Krisztina Pohoczky, Eva Csosz, Adam Simon, Andras Javor, Levente Czegledi, Comparative proteome analysis of skeletal muscle between Merino and Tsigai lambs. Small Ruminant Research 158 (2018) 35-41. [IF: 1,210]


Eszter Pakai, Valeria Tekus, Csaba Zsiboras, Zoltan Rumbus, Emoke Olah, Patrik Keringer, Nora Khidhir, Robert Matics, Laszlo Deres, Katalin Ordog, Nikolett Szentes, Krisztina Pohoczky, Agnes Kemeny, Peter Hegyi, Erika Pinter, Andras Garami, The Neurokinin-1 Receptor Contributes to the Early Phase of Lipopolysaccharide-Induced Fever via Stimulation of Peripheral Cyclooxygenase-2 Protein Expression in Mice. Frontiers in Immunology 9 (2018) 166.  [IF: 4,716]


Nikolett Szarka, Mallikarjuna R. Pabbidi, Krisztina Amrein, Endre Czeiter, Gergely Berta, Krisztina Pohoczky, Zsuzsanna Helyes, Zoltan Ungvari, Akos Koller, Andras Buki, Peter Toth, Traumatic brain injury impairs myogenic constriction of cerebral arteries: role of mitochondria-derived H2O2 and TRPV4-dependent activation of BKCa channels. Journal of Neurotrauma 35 (2018) 930-939.  [IF: 3,754]

 

2017

 

Miklós Poór, Afshin Zand, Lajos Szente, Beáta Lemli, Sándor Kunsági-Máté, Interaction of α- and β-zearalenols with β-cyclodextrins. Molecules 22 (2017) 1910. [IF: 3,098] 

 

Miklós Poór, Mónika Bálint, Csaba Hetényi, Beatrix Gődér, Sándor Kunsági-Máté, Tamás Kőszegi, Beáta Lemli, Investigation of non-covalent interactions of aflatoxins (B1, B2, G1, G2, and M1) with serum albumin. Toxins 9 (2017) 339. [IF: 3,273]

 

Tamás Kőszegi, Nikolett Sali, Maja Raknić, Zoltán Horváth-Szalai, Rita Csepregi, Marijana Zovko Končić, Nóra Papp, Miklós Poór, A novel luminol-based enhanced chemiluminescence antioxidant capacity microplate assay for use in different biological matrices. Journal of Pharmacological and Toxicological Methods 88 (2017) 153-159. [IF: 2,269]

 

Miklós Poór, Sándor Kunsági-Máté, Mónika Bálint, Csaba Hetényi, Zsófia Gerner, Beáta Lemli, Interaction of mycotoxin zearalenone with human serum albumin. Journal of Photochemistry and Photobiology B: Biology 170 (2017) 16-24. [IF: 3,165]

 

Miklós Poór, Gabriella Boda, Paul W Needs, Paul A Kroon, Beáta Lemli, Tímea Bencsik, Interaction of quercetin and its metabolites with warfarin: Displacement of warfarin from serum albumin and inhibition of CYP2C9 enzyme. Biomedicine & Pharmacotherapy 88 (2017) 574-581. [IF: 3,457]

 

Miklós Poór, Balázs Németi, Zoltán Gregus, Effects of phosphate binders on the gastrointestinal absorption of arsenate and of an SGLT2 inhibitor drug on the urinary excretion of arsenite in mice. Environmental Toxicology and Pharmacology 49 (2017) 179-187. [IF: 2,776]

 

2016

 

Miklós Poór, Gergely Matisz, Sándor Kunsági-Máté, Diána Derdák, Lajos Szente, Beáta Lemli, Fluorescence spectroscopic investigation of the interaction of citrinin with native and chemically modified cyclodextrins. Journal of Luminescence 172 (2016) 23-28. [IF: 2,686]

 

Miklós Poór, Zita Zrínyi, Tamás Kőszegi, Structure related effects of flavonoid aglycones on cell cycle progression of HepG2 cells: Metabolic activation of fisetin and quercetin by catechol-O-methyltransferase (COMT). Biomedicine & Pharmacotherapy 83 (2016) 998-1005. [IF: 2,759]

 

Tamás Kőszegi, Miklós Poór, Ochratoxin A: Molecular interactions, mechanisms of toxicity and prevention at the molecular level. Toxins (Basel) 8 (2016) 111. [IF: 3,030]


Nikolett Sali, Miklós Poór, Sándor Nagy, Tamás Kőszegi, Multiparametric luminescent cell viability assay in toxicology models: a critical evaluation. Journal of Pharmacological and Toxicological Methods 79 (2016) 45-54. [IF: 2,238]

 

2015

 

Balázs Németi, Miklós Poór, Zoltán Gregus, A high-performance liquid chromatography-based assay of glutathione transferase omega 1 supported by glutathione or non-physiological reductants. Analytical Biochemistry 469 (2015) 12-18. [IF: 2,243]


Balázs Németi, Miklós Poór, Zoltán Gregus, Reduction of the pentavalent arsenical dimethylarsinic acid and the GSTO1 substrate S-(4-Nitrophenacyl)glutathione by rat liver cytosol: Analyzing the role of GSTO1 in arsenic reduction. Chemical Research in Toxicology 28 (2015) 2199-2209. [IF: 3,025]


Honglei Zhao, Emmanouil G. Sifakis, Noriyuki Sumida, Lluís Millán-Ariño, Barbara A. Scholz, J. Peter Svensson, Xingqi Chen, Anna L. Ronnegren, Carolina Diettrich Mallet de Lima, Farzaneh Shahin Varnoosfaderani, Chengxi Shi, Olga Loseva, Samer Yammine, Maria Israelsson, Li-Sophie Rathje, Balázs Németi, Erik Fredlund, Thomas Helleday, Márta P. Imreh, Anita Göndör, PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription. Molecular cell 59 (2015) 984-997. [IF: 13,958]


Miklós Poór, Sándor Kunsági-Máté, Lajos Szente, Gergely Matisz, Györgyi Secenji, Zsuzsanna Czibulya, Tamás Kőszegi, Interaction of ochratoxin A with quaternary ammonium beta-cyclodextrin. Food Chemistry 172 (2015) 143-149. [IF: 4,052]


Miklós Poór, Sándor Kunsági-Máté, Nikolett Sali, Tamás Kőszegi, Lajos Szente, Beáta Peles-Lemli, Interactions of zearalenone with native and chemically modified cyclodextrins and their potential utilization. Journal of Photochemistry and Photobiology B: Biology 151 (2015) 63-68. [IF: 3,035]


Miklós Poór, Beáta Lemli, Mónika Bálint, Csaba Hetényi, Nikolett Sali, Tamás Kőszegi, Sándor Kunsági-Máté, Interaction of citrinin with human serum albumin. Toxins (Basel) 7 (2015) 5155-5166. [IF: 3,571]