Anatómiai Intézet

 

Anatómiai Intézet publikációi 2013-2018

Publications of the Department of Anatomy 2013-2018

 

 2018

1. Bognar Z, Fekete K, Bognar R, Szabo A, Vass RA, Sumeg B. Amiodarone’s major metabolite, desethylamiodarone induces apoptosis in human cervical cancer cells. Can J Physiol Pharmacol 96(10): 1004-1011.

2. Feher M, Gaszner B, Tamas A, Gil-Martinez AL, Fernandez-Villalba E, Herrero MT, Reglodi D. Alteration of the PAC1 Receptor Expression in the Basal Ganglia of MPTP-Induced Parkinsonian Macaque Monkeys. Neurotox Res 33(4): 702-715.

3. Furedi N, Miko A, Gaszner B, Feller D, Rostas I, Tenk J, Solymar M, Balasko M, Petervari E. Activity of the hypothalamic melanocortin system decreases in middle-aged and increases in old rats. J Gerontol A Biol Sci Med Sci 73(4): 438-445.

4. Jozsa G, Szegeczki V, Palfi A, Kiss T, Helyes Zs, Fülöp B, Cserhati Cs, Daróczi L, Tamás A, Zákány R, Reglődi D, Juhász T. Signalling Alterations in Bones of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Gene Deficient Mice. Int J Mol Sci 19(9): pii: E2538.

5. Jungling A, Reglodi D, Tamas A. Review on the neuroprotective effects of environmental enrichment in models of Parkinson’s disease. Clin Pharmacol Transl Med 2(2): 101-107.

6. Kiss P. Where variations are most important: How to teach human anatomy to medical students. Int J Anat Var 11(2): 73-74.

7. Kovács LÁ, Schiessl JA, Nafz AE, Csernus V, Gaszner B. Both Basal and Acute Restraint Stress-Induced c-Fos Expression Is Influenced by Age in the Extended Amygdala and Brainstem Stress Centers in Male Rats. Front Aging Neurosci 10: 248.

8. Lajko A, Meggyes M, Fulop BD, Gede N, Reglodi D, Szereday L. Comparative analysis of decidual and peripheral immune cells and immune-checkpoint molecules during pregnancy in wild-type and PACAP-deficient mice. Am J Reprod Immunol 80(4): e13035.

9. Mai HN, Chung YH, Shin EJ, Sharma N, Jeong JH, Jang CG, Saito K, Nabeshima T, Reglodi D, Kim HC. IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings. Food Chem Toxicol 116(Pt B): 249-263.

10. Miko A, Poto L, Matrai P, Hegyi P, Furedi N, Garami A, Illes A, Solymar M, Vincze A, Balasko M, Par G, Sarlos P, Bajor J, Tenk J, Rostas I, Petervari E. Gender difference in the effects of interleukin-6 on grip strength - a systematic review and meta-analysis. BMC Geriatr 18(1): 107.

11. Nagy AD, Reddy AB. Redox Clocks: Time to Rethink Redox Interventions. Free Radic Biol Med 119: 3-7.

12. Reglodi D, Atlasz T, Szabo E, Jungling A, Tamas A, Juhasz T, Fulop BD, Bardosi A. PACAP deficiency as a model of aging. Geroscience 40(5-6): 437-452.

13. Reglodi D, Jungling A, Longuespee R, Kriegsmann J, Casadonte R, Kriegsmann M, Juhasz T, Bardosi S, Tamas A, Fulop BD, Kovacs K, Nagy Z, Sparks J, Miseta A, Mazzucchelli G, Hashimoto H, Bardosi A. Accelerated pre-senile systemic amyloidosis in PACAP knockout mice - a protective role of PACAP in age-related degenerative processes. J Pathol 245(4): 478-490.

14. Reglodi D, Illes A, Opper B, Schafer E, Tamas A, Horvath G. Presence and Effects of Pituitary Adenylate Cyclase Activating Polypeptide Under Physiological and Pathological Conditions in the Stomach. Front Endocrin (Lausanne) 9: 90.

15. Reglodi D, Tamas A, Jungling A, Vaczy A, Rivnyak A, Fulop BD, Szabo E, Lubics A, Atlasz T. Protective effects of pituitary adenylate cyclase activating polypeptide against neurotoxic agents. Neurotoxicology 66: 185-194.

16. Reglodi D, Vaczy A, Rubio-Beltran E, MaassenVanDenBrink A. Protective effects of PACAP in ischemia. J Headache Pain 19(1): 19.

17. Reglodi D, Atlasz T, Jungling A, Szabo E, Kovari P, Manavalan S, Tamas A. Alternative routes of administration of the neuroprotective pituitary adenylate cyclase activating polypeptide. Curr Pharm Des 24(33): 3892-3904.

18. Rivnyak A, Kiss P, Tamas A, Balogh D, Reglodi D. Review on PACAP-Induced Transcriptomic and Proteomic Changes in Neuronal Development and Repair. Int J Mol Sci 19(4): pii: E1020.

19. Solymar M, Ivic I, Balasko M, Fulop BD, Toth G, Tamas A, Reman G, Koller A, Reglodi D. Pituitary adenylate cyclase-activating polypeptide ameliorates vascular dysfunction induced by hyperglycaemia. Diab Vasc Dis Res 15(4): 277-285.

20. Szabó D, Szántó Z, Jüngling A, Polgár B, Reglődi D, Cziráki A, Tamás A, Sárszegi Zs. A hypophysis adenilát-cikláz aktiváló polipeptid (PACAP) hatása a kardiovaszkuláris rendszerre. Cardiologia Hungarica 48(2): 129-135.

21. Török D, Somoskői B, Reglődi D, Tamás A, Fülöp B, Cseh S. Hipofízis adenilát cikláz aktiváló polipeptid hatása nőstény egerek ciklusára és az embriófejlődésre - Előzetes eredmények. Magyar Állatorvosok Lapja 140(3): 181-187.

22. Vaczy A, Kovari P, Kovacs K, Farkas K, Szabo E, Kvarik T, Kocsis B, Fulop B, Atlasz T, Reglodi D. Protective role of endogenous PACAP in inflammation-induced retinal degeneration. Curr Pharm Des 24(30): 3534-3542.

 

2017

 

1. Borbely E, Hajna Z, Nabi L, Scheich B, Tekus V, Laszlo K, Ollmann T, Kormos V, Gaszner B, Karadi Z, Lenard L, Paige CJ, Quinn JP, Szolcsanyi J, Pinter E, Keeble J, Berger A, Helyes Z. Hemokinin-1 mediates anxiolytic and anti-depressant-like actions in mice. Brain Behav Immun 2017; 59: 219-232.

2. Farkas J, Kovacs LA, Gaspar L, Nafz A, Gaszner T, Ujvari B, Kormos V, Csernus V, Hashimoto H, Reglodi D, Gaszner B. Construct and face validity of a new model for the three-hit theory of depression using PACAP mutant mice on CD1 background. Neuroscience 2017; 354: 11-29.

3. Farkas J, Sandor B, Tamas A, Kiss P, Hashimoto H, Nagy AD, Fulop BD, Juhasz T, Manavalan S, Reglodi D. Early neurobehavioral development of mice lacking endogenous PACAP. J Mol Neurosci 2017; 61:468-478.

4. Furedi N, Nagy A, Miko A, Berta G, Kozicz TL, Petervari E, Balasko M, Gaszner B. Melanocortin 4 receptor ligands modulate energy homeostasis through urocortin1 neurons of the centrally projecting Edinger-Westphal nucleus. Neuropharmacology 2017;118: 26-37.

5. Heimesaat MM, Reifenberger G, Vicena V, Illes A, Horvath G, Tamas A, Fulop BD, Bereswill S, Reglodi D. Intestinal microbiota changes in mice lacking pituitary adenylate cyclase activating polypeptide (PACAP) – bifidobacteria make the difference. Eur J Microbiol Immunol 2017; 7(3): 187-199.

6. Illes A, Opper B, Reglodi D, Kerenyi M, Czetany P, Boronkai A, Schafer E, Toth G, Fabian E, Horvath G. Effects of pituitary adenylate cyclase activating polypeptide on small intestinal INT 407 cells. Neuropeptides 2017; 65: 106-113.

7. Ivic I, Fulop BD, Juhasz T, Reglodi D, Toth G, Hashimoto H, Tamas A, Koller A. Backup mechanism maintains PACAP/VIP-induced arterial relaxations in PACAP-deficient mice. J Vasc Res 2017; 54: 180-192.

8. Ivic I, Solymar M, Fulop BD, Hashimoto H, Toth G, Tamas A, Koller A, Reglodi D. Aging affects PACAP- and VIP-induced vasomotor responses in arteries of mice. J Vasc Res 2017; 54: 359-366.

9. Jungling A, Reglodi D, Karadi ZN, Horvath G, Farkas J, Gaszner B, Tamas A. Effects of postnatal enriched environment in a model of Parkinson's disease in adult rats. Int J Mol Sci 2017; 18(2). pii: E406.

10.  Keresztes D, Woth G, Nagy BJ, Farkas J, Németh Zs, Maróti P, Rendeki M, Rendeki Sz. Kárhelyszíni elsősegélynyújtás – a Disaster Medic képzés első tapasztalatai tűzoltók körében. Védelem Tudomány 2017; 2:(1) 204-216.

11.  Kovacs-Valasek A, Szabadfi K, Denes V, Szalontai B, Tamas A, Kiss P, Szabo A, Setalo Gy, Reglodi D, Gabriel R. Accelerated retinal aging in PACAP KO mice. Neuroscience 2017; 348:1-10.

12.  Maasz G, Zrinyi Z, Reglodi D, Petrovics D, Rivnyak A, Kiss T, Jungling A, Tamas A, Pirger Z. Pituitary adenylate cyclase-activating polypeptide (PACAP) has neuroprotective function in dopamine-based neurodegeneration developed in rat and snail parkinsonian models. Dis Model Mech 2017; 10: 127-139.

13.  Manavalan S, Getachew B, Manaye KF, Khundmiri SJ, Csoka AB, McKinley R, Tamas A, Reglodi D, Tizabi Y. PACAP protects against ethanol and nicotine toxicity in SH-SY5Y cells: implications for drinking-smoking co-morbidity. Neurotox Res 2017; 32: 8-13.

14.  Nagy AD, Reddy AB. Redox clocks: Time to rethink redox interventions. Free Radic Biol Med 2017; pii: S0891-5849(17)31285-6.

15.  Reglodi D, Renaud J, Tamas A, Tizabi Y, Socías B, Del-Bel E, Raisman-Vozari R. Novel tactics for neuroprotection in Parkinson's disease: Role of antibiotics, polyphenols and neuropeptides. Prog Neurobiol 2017; 155: 120-148.

16.  Rendeki Sz, Keresztes D, Woth G, Mérei Á, Rozanovic M, Rendeki M, Farkas J, Mühl D, Nagy B. Comparison of VividTrac®, Airtraq®, King Vision®, Macintosh Laryngoscope and a Custom-Made Videolaryngoscope for difficult and normal airways in mannequins by novices. BMC Anesthesiology 17 2017; Paper 68. 6 p.

17.  Scheich B, Cseko K, Borbely E, Abraham I, Csernus V, Gaszner B, Helyes Z Higher susceptibility of somatostatin 4 receptor gene-deleted mice to chronic stress-induced behavioral and neuroendocrine alterations. Neuroscience 2017; 346: 320-336.

18.  Scheich B, Vincze P, Szoke E, Borbely E, Hunyady A, Szolcsanyi J, Denes A, Kornyei Z, Gaszner B, Helyes Z. Chronic stress-induced mechanical hyperalgesia is controlled by capsaicin-sensitive neurones in the mouse. Eur J Pain 2017; 21:(8) 1417-1431.

19.  Simon A, Olah J, Komlosi I, Javor A, Nemeth J, Szilvassy Z, Reglodi D, Tamas A, Czegledi L. Changes in expression of neuropeptides and their receptors in hypothalamus and gastrointestinal tract of calorie restricted hens. Acta Biol Hung 2017; 68: 237-247.

20.  Tenk J, Rostas I, Furedi N, Miko A, Solymar M, Soos S, Gaszner B, Feller D, Szekely M, Petervari E, Balasko M. Age-related changes in central effects of corticotropin-releasing factor (CRF) suggest a role for this mediator in aging anorexia and cachexia. Geroscience: Official Journal of the American Aging Association (Age) 2017; 39:(1) 61-72.

21.  Werling D, Banks WA, Salameh TS, Kvarik T, Kovacs LA, Vaczy A, Szabo E, Mayer F, Varga R, Tamas A, Toth G, Biro Zs, Atlasz T, Reglodi D. Passage through the ocular barriers and beneficial effects in retinal ischemia of topical application of PACAP1-38 in rodents. Int J Mol Sci. 2017; 18(3) 675 12p.

22.  Zarandi M , Cai R , Kovacs M , Popovics P , Szalontay L , Cui T , Sha W , Jaszberenyi M , Varga J , Zhang X , Block NL , Rick FG , Halmos G , Schally AV. Synthesis and structure-activity studies on novel analogs of human growth hormone releasing hormone (GHRH) with enhanced inhibitory activities on tumor growth. Peptides 2017; 89: pp. 60-70.

 

2016

Book chapters

1. Atlasz T, Vaczy A, Werling D, Kiss P, Tamas A, Kovacs K, Fabian E, Kvarik T, Mammel B, Danyadi B, Lokos E, Reglodi D. Neuroprotective effects of PACAP in the retina. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, edited by Dora Reglodi and Andrea Tamas. Springer Nature, New York. 2016; pp. 501-527.

2. Fulop DB, Reglodi D, Nemeth A, Tamas A.Pituitary adenylate cyclase activating polypeptide in the auditory system. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, edited by Dora Reglodi and Andrea Tamas. Springer Nature, New York. 2016; pp. 529-546.

3. Horvath G , Illes A, Heimesaat MM, Bardosi A, Bardosi S, Tamas A, Fulop DB,  Opper B , Nemeth J,  Ferencz A, Reglodi D. Protective intestinal effects of pituitary adenylate cyclase activating polypeptide. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, edited by Dora Reglodi and Andrea Tamas, Springer Nature, New York. 2016; pp. 271-288.

4. Horvath G, Nemeth J, Brubel R, Opper B, Koppan M, Tamas A, Szereday L, Reglodi D. Occurrence and functions of PACAP in the placenta. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, edited by Dora Reglodi and Andrea Tamas. Springer Nature, New York. 2016; pp. 389-403.

5. Farkas J, Kovacs LA, Gaszner T, Gaszner B. Using PACAP Heterozygous Mice as Models of the Three Hit Theory of Depression. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, edited by Dora Reglodi and Andrea Tamas, Springer Nature, New York. 2016; pp. 731-741.

6. Juhasz T, Tamas A, Zakany R, Reglodi D. Role of PACAP and VIP signalling in regulation of chondrogenesis and osteogenesis. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, edited by Dora Reglodi and Andrea Tamas, Springer Nature, New York. 2016; pp. 337-353.

7. Reglődi D, Helyes Zs, Németh J, Vass R, Tamás A. PACAP as a potential biomarker – alterations of PACAP levels in human physiological and pathological conditions. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, edited by Dora Reglodi and Andrea Tamas, Springer Nature, New York. 2016; pp. 815-832.

8. Tamas A, Vass RA, Helyes Zs, Csanaky K, Szanto Z, Nemeth J, Reglodi D. Examination of PACAP during lactation. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, edited by Dora Reglodi and Andrea Tamas, Springer Nature, New York. 2016; pp. 833-840.

 

2016 Articles

9. Aschrafi A, Verheijen JM, Gordebeke PM, Olde Loohuis NF, Menting K, Jager A, Palkovits M, Geenen B, Kos A, Martens GJ, Glennon JC, Kaplan BB, Gaszner B, Kozicz T. MicroRNA-326 acts as a molecular switch in the regulation of midbrain urocortin 1 expression. J Psychiatry Neurosci 2016; 41:(5) 342-353.

10.  Bardosi S, Bardosi A, Nagy Zs, Reglodi D. Expression of PACAP and PAC1 receptor in normal human thyroid gland and in thyroid papillary carcinoma. J Mol Neurosci 2016; 60: 171-178.

11.  Edgar RS, Stangherlin A, Nagy AD, Nicoll MP, Efstathiou S, O'Neill JS, Reddy AB. Cell autonomous regulation of herpes and influenza virus infection by the circadian clock. Proc Natl Acad Sci U S A. 2016; 113(36): 10085-90.

12.  Egri P, Fekete Cs, Dénes Á, Reglődi D, Hashimoto H, Fülöp BD, Gereben B. Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates the hypothalamo-pituitary-thyroid (HPT) axis via type 2 deiodinase in male mice. Endocrinology 2016; 157: 2356-66.

13.  Farkas S, Bolcskei K, Markovics A, Varga A, Kis-Varga A, Kormos V, Gaszner B, Horvath C, Tuka B, Tajti J, Helyes Z Utility of different outcome measures for the nitroglycerin model of migraine in mice. Journal of Pharmacological and Toxicological Methods 2016;77: pp. 33-44.

14.  Furedi N, Miko A, Aubrecht B, Gaszner B, Feller D, Rostas I, Tenk J, Soos S, Balasko M, Balogh A, Pap M, Petervari E. Regulatory Alterations of Energy Homeostasis in Spontaneously Hypertensive Rats (SHR). J Mol Neurosci 2016; 59:(4) 521-530.

15.  Cseplo P, Vamos Z, Ivic I, Torok O, Toth A, Koller A. The Beta-1-Receptor Blocker Nebivolol Elicits Dilation of Cerebral Arteries by Reducing Smooth Muscle [Ca2+]i. PLoS One 11:(10) Paper e0164010. 22p.

16.  Kasica N, Podlasz P, Sundvik M, Tamas A, Reglodi D, Kaleczyc J. Protective effects of pituitary adenylate cyclase activating polypeptide (PACAP) against oxidative stress in zebrafish hair cells. Neurotox Res 2016; 30: 633-647.

17.  Kormos V, Gaspar L, Kovacs L, Farkas J, Gaszner T, Csernus V, Balogh A, Hashimoto H, Reglodi D, Helyes Z, Gaszner B. Reduced response to chronic mild stress in PACAP mutant mice is associated with blunted FosB expression in limbic forebrain and brainstem centers. Neuroscience 2016; 330: 335-358.

18.  Kvarik T, Mammel B, Reglodi D, Kovacs K, Werling D, Bede B, Vaczy A, Fabian E, Toth G, Kiss P, Tamas A, Ertl T, Gyarmati J, Atlasz T. PACAP is protective in a rat model of retinopathy of prematurity. J Mol Neurosci 2016; 60: 179-185.

19.  Kvarik T, Mammel B, Reglodi D, Antonelli MC, Farkas J, Tamas A, Ertl T, Atlasz T, Bodzai G, Kiss P, Gyarmati J. Effects of Maternal Stress during Different Periods of Pregnancy on the Early Neurobehavioral Response of Rats. J Neurol Neurosci 2016; 7:(2) Paper 80. 8 p.

20.  Nakamachi T, Ohtaki H, Seki T, Yofu S, Kagami N, Hashimoto H, Shintani N, Baba A, Mark L, Lanekoff I, Kiss P, Farkas J, Reglodi D, Shioda S. PACAP suppresses dry eye signs by stimulating tear secretion. Nat Commun 2016; 7:12034.

21.  Rostas I, Tenk J, Miko A, Furedi N, Soos S, Solymar M, Lengyel A, Szekely M, Gaszner B, Feller D, Petervari E, Balasko M. Age-related changes in acute central leptin effects on energy balance are promoted by obesity. Exp Gerontol 2016; 85: 118-127.

22.  Sandor B, Fintor K, Reglodi D, Fulop DB, Helyes Z, Szanto I, Nagy P, Hashimoto H, Tamas A. Structural and Morphometric Comparison of Lower Incisors in PACAP-Deficient and Wild-Type Mice. J Mol Neurosci 2016; 59: 300-308.

23.  Scheich B, Gaszner B, Kormos V, Laszlo K, Adori C, Borbely E, Hajna Z, Tekus V, Bolcskei K, Abraham I, Pinter E, Szolcsanyi J, Helyes Z. Somatostatin receptor subtype 4 activation is involved in anxiety and depression-like behavior in mouse models. Neuropharmacology 2016; 101: 204-215.

24.  Szabadfi K, Reglodi D, Szabo A, Szalontai B, Valasek A, Setalo Gy. Jr, Kiss P, Tamas A, Wilhelm M, Gabriel R. Pituitary adenylate cyclase activating polypeptide, a potential therapeutic agent for diabetic retinopathy in rats: focus on the vertical information processing pathway. Neurotox Res 2016; 29: 432-46.

25.  Tamas A, Javorhazy A, Reglodi D, Sarlos DP, Banyai D, Semjen D, Nemeth J, Lelesz B, Fulop BD, Szanto Z. Examination of PACAP-like immunoreactivitiy in urogenital tumor samples. J Mol Neurosci 2016; 59: 177-183.

26.  Tenk J, Rostas I, Furedi N, Miko A, Soos S, Solymar M, Gaszner B, Szekely M, Petervari E, Balasko M. Acute central effects of corticotropin-releasing factor (CRF) on energy balance: effects of age and gender. Peptides 2016; 85: 63-72.

27.  Vaczy A, Reglodi D, Somoskeoy T, Kovacs K, Lokos E, Szabo E, Tamas A, Atlasz T. The protective role of PAC1-receptor agonist maxadilan in BCCAO-induced retinal degeneration. J Mol Neurosci 2016; 60: 186-194.

28.  Werling D, Reglodi D, Banks WA, Salameh TS, Kovacs K, Kvarik T, Vaczy A, Kovacs L, Mayer F, Danyadi B, Lokos E, Tamas A, Toth G, Biro Zs, Tamas A, Atlasz T. Ocular delivery of PACAP1-27 protects the retina from ischemic damage in rodents. Invest Ophthalmol Vis Sci 2016; 57: 6683-6691.

 

2015

1. Banki E, Sosnowska D, Tucsek Zs, Gautami T, Toth P, Tarantini S, Tamas A, Helyes Zs, Reglodi D, Sonntag WE, Csiszar A, Ungvari Z. Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide (PACAP) impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci 2015; 70(6): 665-74.

2. Bardos T, Vancsodi J, Farkas B, Fazekas A, Nagy SA, Bogner P, Vermes C, Than P. Pilot Study of Cartilage Repair in the Knee Joint with Multiply Incised Chondral Allograft. Cartilage. 2015; 6(2): 73-81.

3. Csikós Á, Simon Á, Homonai K, Gulyás G, Tizsa Á, Tamás A, Reglődi D, Jávor A, Czeglédi L. Polimorfizmus keresése szarvasmarha hipofízis adenilát cikláz aktiváló polipeptid 5. exonjában. Acta Agraria Debreceniensis 2015; 65: 17-20.

4. Helyes Z, Kun J, Dobrosi N, Sándor K, Németh J, Perkecz A, Pintér E, Szabadfi K, Gaszner B, Tékus V, Szolcsányi J, Steinhoff M, Hashimoto H, Reglődi D, Bíró T. Pituitary Adenylate Cyclase-Activating Polypeptide Is Upregulated in Murine Skin Inflammation and Mediates Transient Receptor Potential Vanilloid-1-Induced Neurogenic Edema. J Invest Dermatol 2015; 135:(9) 2209-2218.

5. Horvath G, Kiss P, Nemeth J, Lelesz B, Tamas A, Reglodi D. Environmental enrichment increases PACAP levels in the CNS of adult rats. Neuroendocrinol Lett 2015; 36: 143-147.

6. Horvath G, Reglodi D, Farkas J, Vadasz Gy, Mammel B, Kvarik T, Bodzai G, Kiss-Ills B, Farkas D, Matkovits A, Sridharan M, Gaszner B, Tamas A, Kiss P. Perinatal positive and negative influences on the early neurobehavioral reflex and motor development. Book chapter in: Perinatal Programming and Development. Advances in Neurobiology 2015; 10:149-67. Springer. Ed.: M. Antonelli.

7. Juhasz T, Helgadottir SL, Reglodi D, Tamas A, Zakany R. Signalisation of VIP and PACAP in chondrogenesis and osteogenesis. Peptides 2015; 66: 51-7.

8. Juhasz T, Szentleleky E, Szucs Somogyi Cs, Takacs R, Dobrosi N, Engler M, Tamas A, Reglodi D, Zakany R. Pituitary adenylate cyclase activating polypeptide (PACAP) pathway is induced by mechanical load and reduces the activity of hedghog signalling in chondrogenic micromass cell cultures. Int J Mol Sci 2015; 16: 17344-67.

9. Krajcs N, Hernádi L, Pirger Zs, Reglődi D, Tóth G, Kiss T. PACAP modulates acetylcholine-elicited contractions at nicotinic neuromuscular contacts of the Land snail. J Mol Neurosci 2015; 57: 492-500.

10.  Laszlo E, Varga A, Kovacs K, Jancso G, Kiss P, Tamas A, Szakaly P, Fulop B, Reglodi D. Ischemia/reperfusion-induced kidney injury in heterozygous PACAP deficient mice. Transplant Proc 2015; 47: 2210-5.

11.  Macsik LL , Somogyi I , Opper B , BovariBiri J , Pollak E , Molnar L , Nemeth P , Engelmann P. Induction of apoptosislike cell death by coelomocyte extracts from Eisenia andrei earthworms. Mol Immunol 2015; 67:(2) 213-22.

12.  Muller A , Gal N , Betlehem J , Fuller N , Acs P , Kovacs L G , Fusz K , Jozsa R , Olah A. Examination of the interaction of different lighting conditions and chronic mild stress in animal model. Acta Physiol Hung 2015; 102:(3) pp. 301-310.

13.  Nagy AD, Reddy AB. Time dictates: emerging clinical analyses of the impact of circadian rhythms on diagnosis, prognosis and treatment of disease. Clin Med (Lond). 2015; Suppl 6: s50-3.

14.  Nagy AD, Iwamoto A, Kawai M, Goda R, Matsuo H, Otsuka T, Nagasawa M, Furuse M, Yasuo S. Melatonin adjusts the expression pattern of clock genes in the suprachiasmatic nucleus and induces antidepressant-like effect in a mouse model of seasonal affective disorder. Chronobiol Int 2015; 32(4): 447-57

15.  Saghy E, Payrits M, Helyes Zs, Reglodi D, Banki E, Toth G, Couvineau A, Szoke E. Stimulatory effect of Pituitary Adenylate-Cyclase Activating Polypeptide 6-38, M65 and Vasoactive Intestinal Polypeptide 6-28 on trigeminal sensory neurons. Neuroscience 2015; 308: 144-56.

16.  Shibasaki Y, Hayata-Takano A, Hazama K, Nakazawa T, Shintani N, Kasai A, Nagayasu K, Hashimoto R, Tanida N, Katayama T, Matsuzaki S, Yamada K, Taniike M, Onaka Y, Ago Y, Washek JA, Koves K, Reglodi D, Tamas A, Matsuda T, Baba A, Hashimoto H. Atomoxetine reverses locomotor hyperactivity, impaired novel object recognition, and prepulseinhibition impairment in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP). Neuroscience 2015; 297: 95-104.

17.  Szabadfi K, Estrada C, Fernandez-Villalba E, Tarragon E, Setalo Gy, Izura V, Reglodi D, Tamas A, Gabriel R, Herrero MT. Retinal aging in the diurnal Chilean rodent (Octodon degus): histological, ultrastructural and neurochemical alterations of the vertical information processing pathway. Front Cell Neurosci 2015; 9:126.

18.  Szabó I , Bősze S , Orbán E , Sipos É , Halmos G , Kovács M , Mező G. Comparative in vitro biological evaluation of daunorubicin containing GnRHI and GnRHII conjugates developed for tumor targeting. J Pept Sci 2015; 21:(5) 426-435.

 

2014

1. Banki E, Hajna Zs, Kemény Á, Botz B, Nagy P, Bölcskei K, Tóth G, Reglődi D, Helyes Zs. The selective PAC1 receptor agonist maxadilan inhibits neurogenic vasodilation and edema formation in the mouse skin. Neuropharmacology 2014; 85: 538-547.

2. Banki E, Kovacs K, Nagy D, Juhasz T, Degrell P, Csanaky K, Kiss P, Jancso G, Toth G, Tamas A, Reglodi D. Molecular mechanisms underlying the nephroprotective effects of PACAP in diabetes. J Mol Neurosci 2014; 54: 300-309.

3. Banki E, Pakai E, Gaszner B, Zsiboras Cs, Czett A, Bhuddi PRP, Hashimoto H, Toth G, Tamas A, Reglodi D, Garami A. Characterization of the thermoregulatory response to pituitary adenylate cyclase-activating polypeptide in rodents. J Mol Neurosci 2014; 54: 543-554.

4. Botz B, Bölcskei K, Kereskai L, Kovács M, Németh T, Szigeti K, Horváth I, Máthé D, Hashimoto H, Reglődi D, Szolcsányi J, Pintér E, Mócsai A, Helyes Zs. Differential regulatory role of Pituitary Adenylate-Cyclase Activating Polypeptide in the serum-transfer-induced arthritis model. Arthritis Rheumatism 2014; 66: 2739-2750.

5. Brown D, Tamas A, Reglodi D, Tizabi Y. PACAP protects against inflammatory-mediated toxicity in dopaminergic SH-SY5Y cells: implication for Parkinson’s disease. Neurotox Res 2014; 26: 230-239.

6. Bukovics P, Czeiter E, Amrein K, Kovacs N, Pal J, Tamas A, Bagoly T, Helyes Zs, Buki A, Reglodi D. Changes of PACAP level in cerebrospinal fluid and plasma of patients with severe traumatic brain injury. Peptides 2014; 60: 18-22.

7. Csanaky K, Doppler W, Tamas A, Kovacs K, Toth G, Reglodi D. Influence of terminal differentiation and PACAP on the cytokine, chemokine and growth factor secretion of mammary epithelial cells. J Mol Neurosci 2014; 52: 28-36.

8. Csiszar A, Gautam T, Sosnowska D, Tarantini S, Banki E, Tucsek Z, Toth P, Losonczy G, Koller A, Reglodi D, Giles CB, Wren J, Sonntag WE, Ungvari ZI. Caloric restriction confers anti-oxidative, pro-angiogenis and anti-inflammatory effects preserving a youthful phenotype in rat cerebromicrovascular endothelial cells. Am J Physiol Heart Circ Physiol 2014;307: H292-306.

9. Danyadi B, Szabadfi K, Reglodi D, Mihalik A, Danyadi T, Kovacs Zs, Batai I, Tamas A, Kiss P, Toth G, Gabriel R. PACAP application improves functional outcome of chronic retinal ischemic injury in rats – evidence from electroretinographic measurements. J Mol Neurosci 2014; 54: 293-299.

10.  Hazama K, Hayata-Takano A, Uetsuki K, Kasai A, Encho N, Shintani N, Nagayasu K, Hashimoto R, Reglodi D, Miyakawa T, Nakazawa T, Baba A, Hashimoto H. Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice. PLoS One 2014; 9: e89153.

11.  Heimesaat MM, Dunay IR, Bölke S, Fischer A, Grundmann U, Alutis M, Kühl AA, Tamas A, Toth G, Dunay MP, Göbel UB, Reglődi D, Bereswill S. Pituitary adenylate cyclase activating polypeptide ameliorates experimnetal acute ileitis and extra-intestinal sequelae. PLoS One 2014; 9(9): e108389.

12.  Horváth G, Reglődi D, Brubel R, Halász M, Barakonyi A, Tamás A, Fábián E, Opper B, Tóth G, Cohen M, Szereday L. Investigation of the possible functions of PACAP in human trophoblast cells. J Mol Neurosci 2014; 54: 320-330.

13.  Juhasz T, Matta Cs, Katona E, Somogyi Cs, Takacs R, Gergely P, Csernoch L, Panyi Gy, Toth G, Reglodi D, Tamas A, Zakany R. Pituitary adenylate cyclase activating polypeptide (PACAP) signalling exerts chondrogenesis promoting and protecting effects: implication of calcineurin as a downstream target. PLoS One 2014; 9:e91541.

14.  Juhasz T, Matta Cs, Katona É, Somogyi Cs, Takács R, Hajdú T, Helgadottir SL, Fodor J, Csernoch L, Tóth G, Bakó É, Reglődi D, Tamás A, Zákány R. Pituitary adenylate cyclase activating polypeptide (PACAP) signalling enhances osteogenesis in UMR-106 cell line. J Mol Neurosci 2014; 54: 555-573.

15.  Laszlo E, Kiss P, Horváth G, Szakály P, Tamás A, Reglődi D. Review on the effects of pituitary adenylate cyclase activating polypeptide in renal ischemia/reperfusion. Acta Biol Hung 2014; 65: 369-78.

16.  Maasz G, Pirger Z, Reglodi D, Petrovics D, Schmidt J, Kiss P, Rivnyak A, Hashimoto H, Avar P, Jambor E, Tamas A, Gaszner B, Mark L Comparative Protein Composition of the Brains of PACAP-Deficient Mice Using Mass Spectrometry-Based Proteomic Analysis. Journal of Molecular Neuroscience 2014;54:(3) pp. 310-319.

17.  Nemeth A, Szabadfi K, Fulop B, Reglodi D, Kiss P, Farkas J, Szalontai B, Gabriel R, Hashimoto H, Tamas A. Examination of calcium-binding protein expression in the inner ear of wild type, heterozygous and homozygous pituitary adenylate cyclase activating polypeptide (PACAP)-knockout mice in kanamycin-induced ototoxicity. Neurotox Res 2014; 25: 57-67.

18.  Pirger Zs, Naskar S, Laszló Z, Kemenes Gy, Reglődi D, Kemenes I. Reversal of age related learning deficiency by the vertebrate pituitary adenylate cyclase activating polypeptide (PACAP) and insulin-like growth factor-1 (IGF-1) in a novel invertebrate model of aging: the pond snail (Lymnaea stagnalis). J Gerontol A Biol Sci Med Sci 2014; 69: 1331-8.

19.  Rozzi SJ, Borelli G, Ryan K, Steiner JP, Reglodi D, Mocchetti I, Avdoshina V. PACAP27 is protective against Tat-induced neurotoxicity. J Mol Neurosci 2014; 54: 485-493.

20.  Sandor B, Fintor K, Felszeghy Sz, Juhász T, Reglődi D, Márk L, Kiss P, Jüngling A, Fülöp BD, Nagy AD, Hashimoto H, Zákány R, Nagy Á, Tamás A. Structural and morphometric comparison of the molar teeth in pre-eruptive developmental stage of PACAP-deficient and wild-type mice. J Mol Neurosci 2014; 54: 331-341.

21.  Szabadfi K, Kiss P, Reglodi D, Fekete EM, Tamas A, Danyadi B, Atlasz T, Gabriel R. Urocortin 2 treatment is protective in excitotoxic retinal degeneration. Acta Physiol Hung 2014; 101: 67-76.

22.    Szabadfi K, Pinter E, Reglodi D, Gabriel R. Neuropeptides, trophic factors, and other substances providing morphofunctional and metabolic protection in experimental models of diabetic retinopathy. Int Rev Cell Mol Biol 2014; 311: 1-121.

23.  Szabadfi K, Szabo A, Kiss P, Reglodi D, Setalo Gy, Tamas A, Toth G, Gabriel R. PACAP promotes neuron survival in early experimental diabetic retinopathy. Neurochem Int 2014; 64: 84-91.

24.  Tsuchida M , Nakamachi T , Sugiyama K , Tsuchikawa D , Watanabe J , Hori M , Yoshikawa A , Imai N , Kagami N , Matkovits A , Atsumi T , Shioda S. PACAP Stimulates Functional Recovery after Spinal Cord Injury through Axonal Regeneration. J Mol Neurosci 2014; 54:(3) pp. 380-387.

25.  Vamos Z, Ivic I, Cséplő P, Tóth G, Tamás A, Reglődi D, Koller Á. Pituitary adenylate cyclase activating polypeptide (PACAP) induces relaxations of peripheral and cerebral arteries, which are impaired differently by aging. J Mol Neurosci 2014; 54: 535-542.

26.  Werling D, Reglodi D, Kiss P, Toth G, Szabadfi K, Tamas A, Biro Zs, Atlasz T. Investigation of PACAP fragments and related peptides in chronic retinal hypoperfusion. J Ophthalmology 2014;563812.

27.  Wilhelm I, Fazakas Cs, Tamás A, Reglődi D, Krizbai IA. PACAP enhances barrier properties of cerebral microvessels. J Mol Neurosci 2014; 54: 469-476.

28.  Xu L, Janssen D, van der Knaap N, Roubos EW, Leshan RL, Myers MG Jr, Gaszner B, Kozicz T. Integration of stress and leptin signaling by CART producing neurons in the rodent midbrain centrally projecting Edinger-Westphal nucleus. Front Neuroanat 2014; 8: 8.

 

2013

1. Banki E, Degrell P, Kiss P, Kovacs K, Kemeny A, Csanaky K, Duh A, Nagy D, Toth G, Tamas A, Reglodi D. Effect of PACAP treatment on kidney morphology and cytokine expression in rat diabetic nephropathy. Peptides 2013; 42C: 125-130.

2. Botz B, Imreh A, Sandor K, Elekes K, Szolcsanyi J, Reglodi D, Quinn JP, Steward J, Hashimoto H, Zimmer A, Helyes Zs. Role of pituitary adenylate cyclase activating polypeptide and Tac1 gene derived tachykinins in sensory, motor and vascular functions under normal and neuropathic conditions. Peptides 2013; 43: 105-112.

3. Brown D, Tamas A, Reglodi D, Tizabi Y. PACAP Protects Against Salsolinol-Induced Toxicity in Dopaminergic SH-SY5Y Cells: Implication for Parkinson's disease. J Mol Neurosci 2013, 50: 600-607.

4. Csanaky K, Reglődi D, Bánki E, Tarcai I, Márk L, Helyes Zs, Ertl T, Gyarmati J, Horváth K, Sántik L, Tamás A. Examination of PACAP-38-like immunoreactivity in different milk and infant formula samples. Acta Physiol Hung 2013; 100: 28-36.

5. Gasz B , Alotti N , Rácz B , Balatonyi B , Kovács V , Szabados S , Gallyas F , Reglődi D , Jancsó G , Rőth E. Activation of protein kinase and mitogen-activated protein kinase systems and poly(ADP-ribose) polymerase-1 during and following cardiopulmonary bypass. Exp Clin Cardiol 2013; 19:(1) p. x.

6. Horvath G, Reglodi D, Vadasz Gy, Farkas J, Kiss P. Exposure to enriched environment decreases neurobehavioral deficits induced by neonatal glutamate toxicity. Int J Mol Sci 2013; 14: 19054-19066.

7. Kiss P, Szabadfi K, Horvath G, Tamas A, Farkas J, Gabriel R, Reglodi D. Gender-dependent effects of enriched environment and social isolation in ischemic retinal lesion in adult rats. Int J Mol Sci 2013; 14: 16111-16123.

8. Kiss P, Vadasz Gy, Kiss-Illes B, Horvath G, Tamas A, Reglodi D, Koppan M. Enviromental enrichment decreases asphyxia-induced neurobehavioral developmental delay in neonatal rats. Int J Mol Sci 2013; 14: 22258-22273.

9. Kommedal S, Csernus V, Nagy AD. The embryonic pineal gland of the chicken as a model for experimental jet lag. Gen Comp Endocrinol 2013; 188: 226-31.

10.  Kormos V, Gaszner B. Role of neuropeptides in anxiety, stress, and depression: From animals to humans. Neuropeptides 2013; 47:(6) 401-419.

11.  Lengyel Z, Battyáni Z, Szekeres G, Csernus V, Nagy AD. Circadian clocks and tumor biology: what is to learn from human skin biopsies? Gen Comp Endocrinol 2013;188: 67-74.

12.  Lengyel Z , Lovig C , Kommedal S , Keszthelyi R , Szekeres G , Battyani Z , Csernus V , Nagy AD. Altered expression patterns of clock gene mRNAs and clock proteins in human skin tumors. Tumor Biol 2013; 34:(2) pp. 811-819.

13.  Lo Pizzo M , Schiera G , Di Liegro I , Di Liegro CM , Pál J , Czeiter E , Sulyok E , Dóczi T. Aquaporin-4 distribution in control and stressed astrocytes in culture and in the cerebrospinal fluid of patients with traumatic brain injuries. Neurol Sci 2013; 34:(8) pp. 1309-1314.

14.  Nedvig K, Szabo G, Csukád D, Sándor J, Németh J, Kovács K, Reglődi D, Kemény Á, Wéber G, Ferencz A. Examination of cytoprotective and anti-inflammatory effect of PACAP-38 on small bowel autotransplantation. Magyar Sebészet 2013; 66: 250-255.

15.  Opper B , Bognár A , Heidt D , Németh P , Engelmann P. Revising lysenin expression of earthworm coelomocytes. Dev Comp Immunol 2013; 39:(3) pp. 214-218.

16.  Shah NS, Pugh PC, Nam H, Rosenthal DT, van Wijk D, Gaszner B, Kozicz T, Kerman IA. A subset of presympathetic-premotor neurons within the centrally projecting Edinger-Westphal nucleus expresses urocortin-1. J Chem Neuroanat 2013; 52: 25-35.

17.  Wada Y , Nakamachi T , Endo K , Seki T , Ohtaki H , Tsuchikawa D , Hori M , Tsuchida M , Yoshikawa A , Matkovits A , Kagami N , Imai N , Fujisaka S , Usui I , Tobe K , Koide R , Takahashi H , Shioda S. PACAP Attenuates NMDA-Induced Retinal Damage in Association with Modulation of the Microglia/Macrophage Status into an Acquired Deactivation Subtype. J Mol Neurosci 2013; 51:(2) pp. 493-502.