Department of Pathophysiology and Gerontology
The Department The history of the Department of Pathophysiology in Pécs is closely linked to the name of professor Szilárd Donhoffer (1902-1999). He was the founder of the Department: he started his career as a physician in the Clinic of Internal Medicine under the supervision of professor János Ángyán. As an outstanding physician and researcher he was appointed as head of the newly established Department of Pathophysiology in 1949. He was the author the first (single-author) textbook of Pathophysiology that was famous for being extremely difficult and also for requiring rational analytical thinking (1957, 1961). 1964-67 he served as rector of the University, from 1964 he was elected member of the
Contacts
Institute Director: Dr. Ákos Koller, full professor
Address: 7624 Pécs, Szigeti út 12. 2nd floor
Mailing address: 7601 Pécs, Pf.: 99
Phone: +36-72-536-246
Fax: +36-72-536-247
E-mail: 
Research and Thesis Topics for Students
Vasomotor functions of venous microvessels in hyperhomocysteinemia. Normal and abnormal mechanisms activated by hemodynamic forces. (experimental)
Tutor: dr. Ákos Koller
Hypertension-induced abnormalities of microvascular vasomotor functions. (experimental)
Tutor: dr. Ákos Koller
Abnormalities of microvascular vasomotor functions in diabetes mellitus. (experimental)
Tutor: dr. Ákos Koller
Abnormalities of microvascular vasomotor functions in obesity. (experimental)
Tutor: dr. Ákos Koller
The role of the local renin-angiotensin system (located in the vessel wall) in the microvascular vasomotor regulation and its age-related alterations. (experimental)
Tutor: dr. Ákos Koller
The role of ADMA in the development of vasomotor dysfunction. (experimental)
Tutor: dr. Ákos Koller
Senile sarcopenia: development and complications. (experimental)
Tutor: dr. Miklós Székely
The healthcare-related aspects of global climatic changes. (theoretical)
Tutor: dr. Miklós Székely
Age-related changes in peptidergic regulaton of energy balance. (experimental)
Tutors: dr. Miklós Székely, dr. Márta Balaskó
Obesity: insulin and other peptides in body weight regulation. (experimental/theoretical)
Tutors: dr. Miklós Székely, dr. Erika Pétervári
Melanocortins in the regulation of food intake and body temperature. (experimental)
Tutors: dr. Miklós Székely, dr. Erika Pétervári
Abdominal vagal afferentation in energy homeostasis. (experimental)
Tutors: dr. Miklós Székely, dr. Margit Solymár, dr. Garami András
Xenoestrogens and other endocrine disruptors in select disease processes. (literature oriented)
Tutor: dr. János Garai
Endocrinology of catechol-oestrogens. (literature oriented)
Tutor: dr. János Garai
Inflammatory mechanisms in estrogen’s hormonal effect. (literature oriented)
Tutor: dr. János Garai
Enzymatic activity of the macrophage migration inhibitory factor (MIF). (experimental & literature oriented)
Tutor: dr. János Garai
Phytoestrogens’ effectivity in menopause. (clinical/experimental & literature oriented)
Tutors: dr. János Garai, dr. József Bódis (Department of Obstetrics and Gynaecology)
Inflammatory mediators in the pathomechanism of endometriosis (clinical/experimental & literature oriented)
Tutors: dr. János Garai, dr. József Bódis (Department of Obstetrics and Gynaecology)
The role of corticotropin-releasing hormone receptor (CRH) and urocortins in energy homeostasis. (experimental)
Tutor: dr. Márta Balaskó
Cholecystokinin and energy homeostasis. (experimental)
Tutor: dr. Márta Balaskó
The effects of perinatal (maternal and foetal) nutritional state on the postnatal development of body weight, body composition and on the potential development of obesity. (experimental)
Tutors: dr. Márta Balaskó, dr. Erika Pétervári, dr. Szilvia Soós
The beneficial effects of phyto-estrogens and other dietary polyphenols on the respiratory system. (literature oriented)
Tutor: dr. Márta Balaskó, dr. Szilvia Soós
The role of leptin in energy balance: age- and nutritional state-related alterations. (experimental)
Tutor: dr. Erika Pétervári
The role of neuropeptide Y (NPY) in energy balance: age- and nutritional state-related alterations. (experimental)
Tutor: dr. Erika Pétervári
Circadian changes in core temperature and spontaneous activity of rodents: age- and nutritional state-related alterations. Biotelemetric studies. (experimental)
Tutors: dr. Erika Pétervári, dr. Margit Solymár
The central regulatory role of insulin in energy balance: age- and nutritional state-related alterations. (experimental)
Tutor: dr. Szilvia Soós
A hot topic for feverish student research: the (patho)physiology of TRPV1. (theoretical/experimental)
Tutor: dr. András Garami
The role of neurokinin-1 (NK1) receptor in processes of energy balance. (theoretical/experimental)
Tutor: dr. Andras Garami
