The Cytoskeletal System

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2020-2021

Thematik

The cytoskeletal system is composed of different proteins networks. The cytoskeleton has versatile structural and functional features, which are essential for almost all cellular processes. The dysfunctioning of the cytoskeleton can often results in pathological alterations of cellular functions, which can lead to diseases. In the first module the course we discuss the components and properties of the cytoskeletal protein networks. The second module lays special emphasis on presenting the pathological alterations of the cytoskeletal system and the underlying diseases.
I. module: Components and functions of the cytoskeleton.
II. module: Pathological alterations and diseases related to the cytoskeleton.
III. module: Biophysical approaches in the investigation of the cytoskeleton.

Vorlesungen

• 1. Introduction - Dr. Bugyi Beáta
• 2. Structure, dynamics and biological functions of cytoskeletal polymers 1 - Dr. Bugyi Beáta
• 3. Structure, dynamics and biological functions of cytoskeletal polymers 2 - Dr. Bugyi Beáta
• 4. Cytoskeletal polymers as potential therapeutic targets - Dr. Gaszler Péter
• 5. Case study: pathogens - Dr. Bugyi Beáta
• 6. Case study: myopahties - Dr. Bukovics Péter
• 7. Case study: carcinogenesis - Dr. Gaszler Péter
• 8. Case study: Actin binding proteins as biomarkers - Dr. Bukovics Péter
• 9. Case study: Wound healing and tissue regeneration (epidermolysis bullosa simplex) - Dr. Gaszler Péter
• 10. Case study: Therapeutic approaches targeting the microtubule cytoskeleton - Dr. Bukovics Péter
• 11. Students’ presentations - Dr. Bugyi Beáta
• 12. Students’ presentations - Dr. Bugyi Beáta

Praktika

Seminare

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

http://biofizika.aok.pte.hu

Skript

Empfohlene Literatur

Jonathon Howard: Mechanics of Motor Proteins and the Cytoskeleton, 2005
S. Trachtenberg: The Prokaryotic Cytoskeleton: A Written Symposium, Journal of Molecular Microbiology and Biotechnology, 2006
Leslie P. Gartner, James L. Hiatt (eds.): Color Textbook of Histology 3, illustrated, revised, Saunders/Elsevier, 2007
Online materials on departmental website (http://biofizika.aok.pte.hu)

Voraussetzung zum Absolvieren des Semesters

Maximum of 25 % absence allowed

Semesteranforderungen

The grading is based on short presentations (5-10 min) by the students related to the topics covered by the course.

Möglichkeiten zur Nachholung der Fehlzeiten

None.

Prüfungsfragen

Can be found on the departmental website (http://biofizika.aok.pte.hu).

Prüfer

Praktika, Seminarleiter/innen

• Dr. Bugyi Beáta
• Dr. Bukovics Péter
• Dr. Gaszler Péter