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The Medical Aspects of Human Population Genetics

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Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2020-2021

Lehrbeauftragte/r

Dr. Tímea VARJAS (vtimi_68@yahoo.com), assistant professor

Department of Public Health Medicine

Fachangaben

Kode des Fachs/Kurses: OXF-PEG-h-T  |  2 ECTS  |  General Medicine |  Optional modul  |  both semesters

Voraussetzungen: keine

Semesterwochenstunden

24 Vorlesungen + 0 Praktika + 0 Seminare = Insgesamt 24

Zahl der Kursteilnehmer für den Kurs

min. 3 – max. 35

Erreichbar als Campus-Kurs für 10 Teilnehmer. Campus-Fakultäten: ETK GYTK TTK

Thematik

Throughout the course, we intend to give enlightenment regarding the practical side of detecting genetic differences between human populations therefore students may familiarize themselves with the conceptual background and medical aspects of the population genetics. The course also intends to show the relation between different disease spectrums and populations by international studies focusing on the detection of rare diseases, origin related researches, migration patterns and forensic medicine.

Vorlesungen

  • 1. Introduction of population genetics. - Bérczi Bálint Dániel
  • 2. Historical background, basic principles (darwinism and lamarckism, role of migration) - Bérczi Bálint Dániel
  • 3. Factors determining phenotype. - Bérczi Bálint Dániel
  • 4. Genotype, inherited epigenetic factors, non-inherited environmental factors. The industrial melanism. - Bérczi Bálint Dániel
  • 5. Genotype and allele frequencies. - Bérczi Bálint Dániel
  • 6. The Hardy-Weinberg principle and medical examples. - Bérczi Bálint Dániel
  • 7. The Four evolutionary forces. - Bérczi Bálint Dániel
  • 8. Mutation and polymorphism - the author of variation. - Bérczi Bálint Dániel
  • 9. Single nucleotide polymorphisms (SNPs) and diseases. What is the link between? - Bérczi Bálint Dániel
  • 10. Allelic, dominant, recessive and codominant genetic models to associate SNPs with risk. - Bérczi Bálint Dániel
  • 11. Human Genome Project, The International HapMap Project, The 1000Genomes Project. - Bérczi Bálint Dániel
  • 12. Ethical issues of genotyping. - Bérczi Bálint Dániel
  • 13. Natural selection - the editor - Bérczi Bálint Dániel
  • 14. Genetic drift - the randomizer - Bérczi Bálint Dániel
  • 15. Gene flow - the homogenizer - Bérczi Bálint Dániel
  • 16. The genetic distance between ethnic groups. The mitochondrial Eve - Bérczi Bálint Dániel
  • 17. Human origin related researches - The application of chromosome Y. - Bérczi Bálint Dániel
  • 18. Archeogenetics, microorganism related investigations in fossil bones and mummies. - Bérczi Bálint Dániel
  • 19. Application of population genetics in Forensic Medicine. - Bérczi Bálint Dániel
  • 20. Next generation sequencing technologies in Forensic Medicine. - Bérczi Bálint Dániel
  • 21. Various disease spectrums in various ethnic groups. - Bérczi Bálint Dániel
  • 22. The example of ethnic specific pattern of genetic variants in ESR1 and the risk of breast cancer. - Bérczi Bálint Dániel
  • 23. Composition of population genetics researches. - Bérczi Bálint Dániel
  • 24. Methodology and possible workflows from planning to bioinformatics. - Bérczi Bálint Dániel

Praktika

Seminare

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

Educational material will be uploaded on Neptun.

Skript

Empfohlene Literatur

Voraussetzung zum Absolvieren des Semesters

Maximum of 15 % absence allowed

Semesteranforderungen

A simple choice test has to be done on the last lecture.

Möglichkeiten zur Nachholung der Fehlzeiten

There are no make-up classes.

Prüfungsfragen

Neptun

Prüfer

Praktika, Seminarleiter/innen