Pharmacology 2

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2022-2023

Thematik

The general aim of the subject is to provide the dentistry students with all the basic information in pharmacology necessary to understand the actions of drugs and the clinical pharmacotherapy. Pharmacology can be defined as the study of the manner in which the function of living systems is affected by chemical agents. Therefore, the students should be familiar with the basic knowledge of the physiological, pathophysiological and biochemical background of the pharmacological and therapeutic approaches. On the other hand, drug therapy is closely related to the clinical aspects of diseases.
The following topics will be dealt with. Opioid analgesic drugs, cyclooxygenase inhibitors. Pharmacology of the central nervous system: general anaesthetics, antipsychotic drugs, antidepressants, antianxiety and hypnotic drugs, antiepileptics, treatment of neurodegenerative disorders, drug abuse and dependence. Pharmacology of the respiratory and the gastrointestinal tract. Pharmacology of the endocrine system: pituitary hormones, corticosteroids, reproductive system, thyroid hormones, antithyroid drugs, insulin, glucagon and oral hypoglycemic agents, vitamin D, treatment of osteoporosis. Chemotherapy: sulphonamides and trimethoprim, fluoroquinolones, beta-lactam antibiotics, aminoglycosides, antituberculotics. Antifungal drugs, antiviral agents, antiseptics and disinfectants.

Vorlesungen

• 1. General anaesthetics I - Dr. Tamasikné Dr. Helyes Zsuzsanna
• 2. General anaesthetics II - Dr. Tamasikné Dr. Helyes Zsuzsanna
• 3. Anxiolytic and hypnotic drugs - Dr. Sánticsné Dr. Pintér Erika
• 4. Antipsychotics - Dr. Tamasikné Dr. Helyes Zsuzsanna
• 5. Antidepressants - Dr. Tamasikné Dr. Helyes Zsuzsanna
• 6. Antiepileptics - Dr. Pozsgai Gábor
• 7. Opioid analgesics I - Dr. Pozsgai Gábor
• 8. Opioid analgesics II - Dr. Pozsgai Gábor
• 9. Calcium channel blockers - Dr. Tamasikné Dr. Helyes Zsuzsanna
• 10. Drugs acting on the renin-angiotensin-aldosterone system - Dr. Sánticsné Dr. Pintér Erika
• 11. Diuretics - Dr. Pozsgai Gábor
• 12. Therapy of congestive heart failure - Dr. Tamasikné Dr. Helyes Zsuzsanna
• 13. Antianginal drugs - Dr. Sánticsné Dr. Pintér Erika
• 14. Pharmacotherapy of hypertension - Dr. Sánticsné Dr. Pintér Erika

Praktika

Seminare

• 1. Pharmacotherapy of neurodegenerative disorders. Centrally acting muscle relaxants
• 2. Hypothalamic and pituitary hormones
• 3. Thyroid hormones, antithyroid drugs
• 4. Corticosteroids I
• 5. Corticosteroids II
• 6. Estrogens, anti-estrogens, progestogens, antiprogestogens. Postmenopausal hormone replacement therapy
• 7. Hormonal contraceptives. Androgens, anabolic steroids and antiandrogens
• 8. Parathormone, calcitonin, vitamin D and pharmacotherapy of osteoporosis
• 9. Insulin, insulin analogues
• 10. Oral antidiabetics. Glucagon
• 11. Pharmacotherapy of hyperlipoproteinemias
• 12. Drugs acting on the respiratory system I
• 13. Drugs acting on the respiratory system II
• 14. Consultation on the pharmacology of the central nervous system
• 15. Pharmacotherapy of peptic ulcer
• 16. Emetics, anti-emetics, prokinetic drugs
• 17. Laxatives, antidiarrhoeal drugs
• 18. Choleretic and cholekinetic drugs. Drugs protecting the liver. Pharmacotherapy of inflammatory bowel disease
• 19. Anti-arrhythmic drugs
• 20. Drugs influencing haemostasis I
• 21. Drugs influencing haemostasis II
• 22. Drugs influencing haematopoiesis
• 23. NSAIDs I
• 24. NSAIDs II. Pharmacotherapy of gout
• 25. Immunosuppressants
• 26. Immunosuppressants. Pharmacotherapy of rheumatoid arthritis
• 27. Drug abuse I
• 28. Drug abuse II

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Rang, Dale, Ritter, Moore: Pharmacology, 8th edition, Elsevier Churchill Livingstone, 2015.
B. G. Katzung (ed.): Basic and Clinical Pharmacology, 12th edition, Lange Medical Books/McGraw-Hill, 2012.

Vom Institut veröffentlichter Lehrstoff

Intranet. Department of Pharmacology and Pharmacotherapy. Educational materials.
MeetStreet

Skript

Empfohlene Literatur

Voraussetzung zum Absolvieren des Semesters

For the semester to be accepted total absence should be less than 3 lectures or 6 seminars. Exceeding the absence limit of either lectures or seminars results in the semester not being accepted.

Semesteranforderungen

There is no mid-term examination.

Möglichkeiten zur Nachholung der Fehlzeiten

Not possible

Prüfungsfragen

1. Drug development
2. Basic mechanisms of drug effects
3. Characteristics of the agonist-receptor interaction
4. Signal transduction
5. Tachyphylaxis and tolerance. Antagonism
6. Absorption
7. Distribution
8. Biotransformation
9. Excretion
10. Quantitative pharmacokinetics
11. Cholinergic agonists. Cholinesterase inhibitors
12. Muscarine receptor antagonists
13. Peripheral muscle relaxants
14. Drugs acting on the synthesis, storage, release and elimination of catecholamines
15. Adrenergic receptor agonists
16. Adrenergic receptor antagonists
17. Histamine and histamine receptor antagonists
18. Serotonin, 5-HT receptor agonists and antagonists
19. Eicosanoids
20. Drugs influencing smooth muscles
21. Local anaesthetics
22. Sulfonamides, trimethoprim. Fluoroquinolones
23. β-lactam antibiotics. Glycopeptide antibiotics
24. Tetracyclines, chloramphenicol, linezolid, clindamycin, metronidazole
25. Aminoglycosides. Macrolides
26. Antituberculotics. Antileprotics
27. Antifungal drugs
28. Antiviral drugs
29. Antiseptics and disinfectants
30. Anticancer drugs: alkylating agents, antimetabolites
31. Anticancer drugs: antibiotics, alkaloids, hormones, biological therapy
32. Cytotoxic and embryotoxic adverse effects of drugs. Drug allergy
33. Drug interactions
34. General anaesthetics
35. Anxiolytic and hypnotic drugs
36. Antipsychotics
37. Antidepressants
38. Antiepileptic drugs. Centrally acting muscle relaxants
39. Pharmacotherapy of neurodegenerative disorders
40. Opioid analgesics: morphine and codeine
41. Opioid analgesics: semisynthetic, synthetic drugs and antagonists
42. NSAIDs: aspirin and paracetamol. Pharmacotherapy of gout
43. NSAIDs except aspirin and paracetamol
44. Calcium channel blockers
45. Drugs acting on the renin-angiotensin-aldosterone system
46. Diuretics
47. Pharmacotherapy of congestive heart failure
48. Antianginal drugs
49. Pharmacotherapy of hypertension
50. Anti-arrhythmic drugs
51. Pharmacotherapy of hyperlipoproteinemias
52. Drugs influencing haemostasis
53. Drugs influencing haematopoiesis
54. Drugs acting on the respiratory system: pharmacotherapy of bronchial asthma
55. Drugs acting on the respiratory system: Pharmacotherapy of allergic rhinitis. Antitussive, expectorant and mucolytic drugs
56. Pharmacotherapy of peptic ulcer
57. Emetics, anti-emetics, prokinetic drugs
58. Laxatives, antidiarrhoeal drugs. Choleretic and cholekinetic drugs. Drugs protecting the liver. Pharmacotherapy of inflammatory bowel disease
59. Hypothalamic and pituitary hormones
60. Thyroid hormones and antithyroid drugs
61. Corticosteroids
62. Estrogens, anti-estrogens, progestogens, antiprogestogens
63. Postmenopausal hormone replacement therapy. Hormonal contraceptives
64. Androgens, anabolic steroids and anti-androgens
65. Parathormone, calcitonin, vitamin D and pharmacotherapy of osteoporosis
66. Insulin, insulin analogues. Oral antidiabetic drugs. Glucagon
67. Immunosuppressants. Immunomodulators. Pharmacotherapy of rheumatoid arthritis
68. Drug abuse: General aspects. Opioids, central nervous system depressants
69. Drug abuse: psychomotor stimulants, hallucinogens, cannabis

Prüfer

• Dr. Bölcskei Kata
• Dr. Pozsgai Gábor
• Dr. Sánticsné Dr. Pintér Erika
• Dr. Tamasikné Dr. Helyes Zsuzsanna

Praktika, Seminarleiter/innen

• Dr. Bátai István Zoárd
• Dr. Bölcskei Kata
• Dr. Csekő Kata
• Dr. Horváth Ádám István
• Dr. Hunyady Ágnes
• Dr. Pozsgai Gábor
• Dr. Sánticsné Dr. Pintér Erika
• Dr. Tamasikné Dr. Helyes Zsuzsanna