Modern Drug Developmental Techniques - from the Molecules to the Human Clinical Studies

Daten

Offizielle Daten in der Fachveröffentlichung für das folgende akademische Jahr: 2022-2023

Lehrbeauftragte/r

  • Dr. Szőke Éva

    associate professor,
    Department of Pharmacology and Pharmacotherapy

Semesterwochenstunden

Vorlesungen: 12

Praktika: 0

Seminare: 0

Insgesamt: 12

Fachangaben

  • Kode des Kurses: OTF-MKV-T
  • 1 kredit
  • Biotechnology BSc
  • Optional modul
  • both semesters
Voraussetzungen:

keine

Zahl der Kursteilnehmer für den Kurs:

min. 1 – max. 50

Erreichbar als Campus-Kurs für 50 fő számára. Campus-karok: ÁOK ETK GYTK TTK

Thematik

We will talk about what is the reason of drug development, about the history of drug development. We will compare the traditional drug discovery and modern drug development. Students will learn about target identification and validation, drug design and synthesis, selection and testing of lead molecules. They will learn about in vitro, ex vivo and in vivo preclinical drug development and in vivo animal models od pain, behavioral studies, depression and anxiety. They will learn about clinical phase trials.

Vorlesungen

  • 1. Basic concepts of pharmacology. What is the reason of drug development? - Dr. Szőke Éva
  • 2. History of drug development. - Dr. Szőke Éva
  • 3. Traditional drug discovery and modern drug development. - Dr. Szőke Éva
  • 4. How we identify our drug target? - Dr. Szőke Éva
  • 5. Design and synthesis of drug molecules. - Dr. Szőke Éva
  • 6. Selection and testing of lead molecules. - Dr. Szőke Éva
  • 7. Testing of drug candidates, in vitro preclinical development. - Dr. Szőke Éva
  • 8. Testing of drug candidates, ex vivo preclinical development. - Dr. Szőke Éva
  • 9. In vivo animal experiments in drug development: pain models. - Dr. Szőke Éva
  • 10. In vivo animal experiments in drug development: behavioral studies, depression, anxiety studies. - Dr. Szőke Éva
  • 11. Clinical phase trials. - Dr. Szőke Éva
  • 12. Discussion of papers. - Dr. Szőke Éva

Praktika

Seminare

Materialien zum Aneignen des Lehrstoffes

Obligatorische Literatur

Vom Institut veröffentlichter Lehrstoff

Materials is pdf format.

Skript

Empfohlene Literatur

Voraussetzung zum Absolvieren des Semesters

Maximum of 15 % absence allowed

Semesteranforderungen

A small paper about the topic of the course.

Möglichkeiten zur Nachholung der Fehlzeiten

In agreement with the lecturer.

Prüfungsfragen

1. Basic concepts of pharmacology. What is the reason of drug development?
2. History of drug development.
3. Traditional drug discovery and modern drug development.
4. How we identify our drug target?
5. Design and synthesis of drug molecules.
6. Selection and testing of lead molecules.
7. Testing of drug candidates, in vitro preclinical development.
8. Testing of drug candidates, ex vivo preclinical development.
9. In vivo animal experiments in drug development: pain models.
10. In vivo animal experiments in drug development: behavioral studies, depression, anxiety studies.
11. Clinical phase trials.

Prüfer

Praktika, Seminarleiter/innen