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Biophysical Basics of Diagnostic and Therapeutic Methods

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Data

Official data in SubjectManager for the following academic year: 2020-2021

Course director

Dr. Gábor HILD (gabor.hild@aok.pte.hu), associate professor

Department of Biophysics

Subject data

Code of subject: OXF-DMB-h-T  |  2 credit  |  General Medicine |  Optional module  |  spring

Prerequisites: ODA-BI2-T completed , ODA-EL2-T completed

Number of hours/semester

0 lectures + 0 practices + 24 seminars = total of 24 hours

Course headcount limitations

min. 3 – max. 10 person

Topic

During the course the students get acquainted with the physical basics of the modern medical diagnostic and therapic methods, from a clinical approach. The aim of the course is to underlie or supplement the clinical knowledge with necessary information. During the seminars, wherever possible, practical demonstrations will also be held.

Lectures

Practices

Seminars

  • 1. Introduction
  • 2. Classification of the diagnostic methods
  • 3. Radioactive isotopes. Biological effects of ionizing radiations. Radioprotection
  • 4. Isotope therapy (Brachytherapy), radiotherapy
  • 5. Absorption photometry
  • 6. Fluorescence spectroscopy
  • 7. X-ray radiation: production, detection, absorption. Operation of the diagnostic X-ray instrument. Interpret X-ray image
  • 8. Computed tomography. Manipulation of CT-image (windowing, 3D reconstruction, virtual endoscopy)
  • 9. Isotope diagnostics: Gamma camera, SPECT
  • 10. Isotope diagnostics: Positron emission tomography (PET)
  • 11. LASER: features, absorption, effects on biological tissues
  • 12. LASER: dermatological, ophtalmological, surgical applications. Photodynamic therapy
  • 13. Ultrasound: production and physical features
  • 14. Ultrasound: diagnostic and therapeutic applications
  • 15. Basics of flow cytometry and cell sorting
  • 16. Diagnostic applications of flow cytometry
  • 17. Physical basics of magnetic resonance applications. NMR
  • 18. Magnetic resonance imaging (MRI)
  • 19. Measurements on an educational X-ray instrument
  • 20. Measurements on an educational X-ray instrument
  • 21. Computed tomography measurements on an educational CT instrument
  • 22. Computed tomography measurements on an educational CT instrument
  • 23. Test
  • 24. Test

Reading material

Obligatory literature

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Literature developed by the Department

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Notes

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Recommended literature

Kane, S.A. Introduction to Physics in Modern Medicine, Taylor&Francis, London, 2003
Damjanovich Sándor, Fidy Judit, Szöllősi János (eds.): Medical Biophysics, Medicina, Budapest, 2008

Conditions for acceptance of the semester

Maximum of 25 % absence allowed

Mid-term exams

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Making up for missed classes

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Exam topics/questions

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Examiners

Instructor / tutor of practices and seminars

  • Dr. Hild Gábor
  • Dr. Lukács András Szilárd
  • Dr. Ujfalusi Zoltán