Department of Immunology and Biotechnology · Subjects · Molecular Therapies

Data

Official data in SubjectManager for the following academic year: 2021-2022

Course director

Dr. Péter András ENGELMANN

associate professor,
Department of Immunology and Biotechnology
engelmann.peter@pte.hu

Number of hours/semester

lectures: 14 hours

practices: 0 hours

seminars: 14 hours

total of: 28 hours

Subject data

Code of subject: OBH-013-T
2 kredit
Biotechnology MSc
Specialty in Medical Biotechnology modul
autumn

Prerequisites:

Exam course:

Course headcount limitations

min. 1 – max. 50

Topic

During the course we present the molecular basics of modern therapeutical approaches, we put special emphasis on recombinant protein production and the RNAi based or viral gene therapy. Furthermore, we discuss in detail the gene, protein, or small molecule-based interventions in several disease groups from metabolic malfunctions to pulmonary diseases. Finally, we touch the future technologies in molecular therapy against infectious diseases.

Lectures

1. Introduction, recombinant proteins: expression, applications - Dr. Engelmann Péter András
2. RNAi-based molecular therapy - Dr. Engelmann Péter András
3. Viral-based gene therapy - Dr. Engelmann Péter András
4. Therapeutical approaches in neurodegenerative diseases - Dr. Najbauer József
5. Molecular therapies for inborn diseases - Dr. Mosdósi Bernadett
6. Kinase and non-kinase inhibitors in cancer therapy - Dr. Bellyei Szabolcs
7. Molecular therapeutical approaches in cardiovascular diseases - Deres László
8. Molecular therapies in metabolic diseases - Dr. Najbauer József
9. Molecular therapies in hematological disorders - Dr. Kohl Zoltán
10. Molecular therapeutical approaches in systemic autoimmune diseases - Dr. Minier Tünde
11. Molecular therapies in chronic pulmonary diseases - Dr. Engelmann-Szabó Mariann
12. Novel trends in vaccine development against infectious diseases - Dr. Péterfi Zoltán
13. Bacteriophage therapy - Dr. Schneider György József
14. Consultation - Dr. Engelmann Péter András

Practices

Seminars

1. Protein replacement therapy
2. RNA-i based molecular therapy
3. Viral-based gene therapy
4. Therapeutical approaches in neurodegenerative diseases
5. Molecular therapies for inborn diseases
6. Kinase and non-kinase inhibitors in cancer therapy
7. Molecular therapeutical approaches in cardiovascular diseases
8. Molecular therapies in metabolic disorders
9. Molecular therapies in hematological disorders
10. Molecular therapeutical approaches in systemic autoimmune diseases
11. Molecular therapies in chronic pulmonary diseases
12. Novel trends in vaccine development against infectious diseases
13. Bacteriophage therapy
14. Consultation

Reading material

Obligatory literature

Literature developed by the Department

Notes

Recommended literature

http://medbiotech.aok.pte.hu/en

Conditions for acceptance of the semester

Maximum of 25 % absence allowed

Mid-term exams

Neptun MeetStreet

Making up for missed classes

None

Exam topics/questions