Clinical Laboratory Investigations

Data

Official data in SubjectManager for the following academic year: 2020-2021

Course director

Number of hours/semester

lectures: 24 hours

practices: 0 hours

seminars: 0 hours

total of: 24 hours

Subject data

  • Code of subject: OPG-KLV-T
  • 2 kredit
  • Pharmacy
  • Pharm. theoretical module and practical skills modul
  • autumn
Prerequisites:

OPG-KL2-T parallel , OPO-IMM-T completed , OPO-KTN-T completed

Course headcount limitations

min. 1

Topic

Clinical Laboratory Investigations is a subject based on a solid knowledge in chemistry, biochemistry and physiology. It gives a practical guide to understand and interpret a wide variety of modern laboratory tests by showing the molecular basis of them. The subject includes classic chemical and biochemical methods, immunochemistry, hematology, blood coagulation, toxicology and molecular biology. The major methodological aspects and applications are discussed during the lectures.

Lectures

  • 1. Clinical Biochemistry: analysis of samples obtained from the human body and interpretation of test results. Different factors influencing the results of lab tests. Informational value of test results (reference intervals, statistical approaches). - Dr. Kőszegi Tamás Antal
  • 2. Clinical Biochemistry: analysis of samples obtained from the human body and interpretation of test results. Different factors influencing the results of lab tests. Informational value of test results (reference intervals, statistical approaches). - Dr. Kőszegi Tamás Antal
  • 3. Different laboratory approaches in water and electrolyte disorders. Internal and external quality controls. - Dr. Kőszegi Tamás Antal
  • 4. Different laboratory approaches in water and electrolyte disorders. Internal and external quality controls. - Dr. Kőszegi Tamás Antal
  • 5. Analysis of plasma proteins. Separation techniques and basis of immunochemical methods. - Dr. Horváth-Szalai Zoltán
  • 6. Analysis of plasma proteins. Separation techniques and basis of immunochemical methods. - Dr. Horváth-Szalai Zoltán
  • 7. Analysis of plasma enzymes. Routes of release of enzymes into the extracellular space. Enzymes as tissue markers. - Dr. Horváth-Szalai Zoltán
  • 8. Analysis of plasma enzymes. Routes of release of enzymes into the extracellular space. Enzymes as tissue markers. - Dr. Horváth-Szalai Zoltán
  • 9. Carbohydrate metabolism and laboratory tests in endocrine diseases. - Vassné Dr. Lakatos Ágnes
  • 10. Laboratory tests in endocrine diseases. - Dr. Kőszegi Tamás Antal
  • 11. Laboratory diagnostics of cardiac and skeletal muscle diseases. Inherited and acquired disorders. Importance of the half-life of tested parameters. - Dr. Kőszegi Tamás Antal
  • 12. Laboratory diagnostics of cardiac and skeletal muscle diseases. Inherited and acquired disorders. Importance of the half-life of tested parameters. - Dr. Kőszegi Tamás Antal
  • 13. Iron, porphyrin and hemoglobin metabolism. Automated immunochemical measurements. - Dr. Kőszegi Tamás Antal
  • 14. Iron, porphyrin and hemoglobin metabolism. Automated immunochemical measurements. - Dr. Kőszegi Tamás Antal
  • 15. Automated hematological analyses. - Dr. Kiss Gabriella
  • 16. Disorders of lipid metabolism. - Dr. Kőszegi Tamás Antal
  • 17. Acid-base balance. Methods and interpretation of test results. - Dr. Horváth-Szalai Zoltán
  • 18. Acid-base balance. Methods and interpretation of test results. - Dr. Horváth-Szalai Zoltán
  • 19. Calcium, magnesium and bone metabolism. Laboratory findings in bone diseases. - Dr. Kőszegi Tamás Antal
  • 20. Calcium, magnesium and bone metabolism. Laboratory findings in bone diseases. - Dr. Kőszegi Tamás Antal
  • 21. Laboratory tests in kidney diseases. Tumors and tumor markers. - Dr. Kőszegi Tamás Antal
  • 22. Laboratory tests in kidney diseases. Tumors and tumor markers. - Dr. Kőszegi Tamás Antal
  • 23. Different approaches in liver and gastrointestinal diseases. Basic methods in investigation of disorders in hemostasis. - Dr. Kiss Gabriella
  • 24. Different approaches in liver and gastrointestinal diseases. Basic methods in toxicology and interpretation of results. - Dr. Kőszegi Tamás Antal

Practices

Seminars

Reading material

Obligatory literature

There is no obligatory handbook

Literature developed by the Department

All lectures are accessible at Neptun and/or sent by e-mail in pdf form

Notes

There is no official lecture notes book

Recommended literature

W.J. Marshall, S.K. Bangert: Clinical Chemistry, 7th ed., Mosby Co, 2012, ISBN 9780723437048
G.J. Beckett, S.W. Walker, P. Rae, P. Ashby: Lecture Notes on Clinical Biochemistry, 8th ed., Wiley-Blackwell Co., 2013. ISBN 978-1-4443-9475-7
A. Gaw, M.J. Murphy, R.A. Cowan, D.St.J. O'Reilly, M.J. Stewart, J. Shepherd: Clinical Biochemistry, An Illustrated Colour Text, 4th ed., Churchill Livingstone Elsevier 2008

Conditions for acceptance of the semester

Maximum of 25 % absence allowed

Mid-term exams

One midterm multiple choice is due in October-November
A second midterm multiple choice is due in December
The final grade (mark) is given by evaluation of the combined results of the two midterms

Making up for missed classes

An absence rate of less than 25% is acceptable, no medical or other certificate is necessary.

Exam topics/questions

In every semester new multiple choice questions are given.

Examiners

Instructor / tutor of practices and seminars