Pathophysiology for Dental Students 2

Data

Official data in SubjectManager for the following academic year: 2022-2023

Topic

Pathophysiology for dental students-2 deals with the etiology, time-course and clinical symptoms, as well as with possible pharmacological and other interventions in disorders of the gastrointestinal system, energy balance, intermediary metabolism and the endocrine systems.

Lectures

• 1. Saliva production and its role in dental health and oral mucosal protection. - Dr. Balaskó Márta
• 2. Disorders of gastric filling and emptying. Gastro-esophageal reflux disease. - Dr. Balaskó Márta
• 3. Disorders of gastric juice production. Peptic ulcer. - Dr. Balaskó Márta
• 4. Vomiting and its importance in dental practice. - Dr. Balaskó Márta
• 5. Diarrheas. - Dr. Balaskó Márta
• 6. Maldigestion, malabsorption, bowel obstruction (ileus). - Dr. Balaskó Márta
• 7. Pancreatitis. - Dr. Balaskó Márta
• 8. Pathophysiology of liver functions and their importance in dental practice. - Dr. Balaskó Márta
• 9. Jaundice. Hepatic coma. - Dr. Balaskó Márta
• 10. Vitamins and their importance in dental practice. - Némethné Dr. Tóth Ildikó
• 11. Complete starvation. - Dr. Balaskó Márta
• 12. Partial starvation. - Dr. Balaskó Márta
• 13. Pathophysiology of obesity, metabolic syndrome. - Dr. Balaskó Márta
• 14. Cold- and warm-defense and their disorders. - Dr. Balaskó Márta
• 15. Fever and sickness behavior. - Dr. Balaskó Márta
• 16. Diabetes mellitus. - Dr. Balaskó Márta
• 17. Acute complications of diabetes mellitus syndromes. - Dr. Balaskó Márta
• 18. Chronic complications of diabetes mellitus syndromes. - Dr. Balaskó Márta
• 19. Diabetes mellitus in dentistry. - Dr. Balaskó Márta
• 20. Hypoglycemias. - Dr. Balaskó Márta
• 21. Disorders of protein metabolism. Gout. - Dr. Balaskó Márta
• 22. Disorders of lipid metabolism, pethomechanisms of atherosclerosis. - Dr. Balaskó Márta
• 23. Causes and consequences of hyperprolactinemia. Disorders of growth. - Dr. Balaskó Márta
• 24. Disorders of thyroid functions. - Dr. Balaskó Márta
• 25. Hypo- and hyperfunctions of the adrenal medulla. - Dr. Balaskó Márta
• 26. Hypo- and hyperfunctions of the adrenal cortex. - Dr. Balaskó Márta
• 27. Abnormalities of parathyroid functions and calcium levels, their manifestations in teeth and bones. - Dr. Balaskó Márta
• 28. Pathophysiological aspects of the dental treatment of elderly patients. - Dr. Balaskó Márta

Practices

Seminars

Reading material

Obligatory literature

Székely Miklós (editor) Basic concepts in pathopysiology. Medicina Publishing House Budapest, 2019.

Literature developed by the Department

Lecture and seminar slides will be uploaded to TEAMS.

Notes

M. Székely (ed.): Basic Concepts in Pathophysiology, ÁOK PTE, 2007

Recommended literature

Medical Problems in Dentistry, ed: Crispian Scully, Churchill Livingstone; 7th edition, 2014
S. Silbernagl, F. Lang : Color Atlas of Pathophysiology, Thieme Stuttgart _ New York, 2000

Conditions for acceptance of the semester

Maximum of 15 % absence allowed

Mid-term exams

None

Making up for missed classes

A maximum of 15 % absence is allowed. It corresponds to 4 times 45 minutes.

Exam topics/questions

Saliva production and its role in dental health and oral mucosal protection.
Disorders of gastric filling and emptying. Gastro-esophageal reflux disease.
Vomiting (acute, chronic) and its importance in dental practice.
Peptic ulcer.
Specific malabsorption syndromes, based on the level of the disorder (gastric, pancreatic, hepato-biliary) or on substrate specificity.
Complex malabsorption syndromes.
Diarrhea: causes, pathophysiological forms, consequences.
Bowel obstruction.
Acute pancreatitis: pathophysiology and consequences.
Pathophysiology of chronic pancreatitis.
Pathophysiology of liver disfunctions and their importance in dental practice.
Disorders of intermediary metabolism in general liver cell damage.
Jaundice.
Cirrhosis: causes, mechanisms and consequences. Ascites.
Water-soluble vitamins and their importance in dental practice.
Fat-soluble vitamins and their importance in dental practice.
Complete starvation: occurrence and process.
Partial starvation, anorexia nervosa. Accelerated forms of energetic insufficiency.
Protein deficiency. Protein-calorie malnutrition. Consequences of excessive protein intake.
Etiology and pathogenesis of obesity. Metabolic syndrome.
Consequences of obesity. Therapeutic possibilities.
Cold-defense and cold-induced disorders.
Warm-defense and heat-induced disorders.
Heat stroke and malignant hyperthermia, heat-collapse (heat-induced syncope), heat decompensation.
Fever and sickness-behavior. The biological value of fever.
Hyperglycemia and glucose-tolerance tests. Diagnosis of diabetes mellitus.
General pathobiochemistry of diabetes mellitus syndrome.
Etiology and pathogenesis of DM1.
Etiology and pathogenesis of DM2.
Diabetic ketoacidosis (DKA) and ketoacidotic coma.
Diabetic hyperosmolar syndrome (HHS) and coma.
Late complications of diabetes mellitus.
Hypoglycemia.
Pathobiochemistry of LDL-metabolism. Primary and secondary hyperlipoproteinemia.
Atherosclerosis: its cellular and molecular pathophysiology.
Gout.
Disorders of the hypothalamo-pituitary system. Pituitary insufficiency.
Pituitary adenomas. Hyperprolactinemia.
Pathophysiology of growth.
Hyperthyroidism.
Hypothyroidism.
Disturbances of the adrenal medulla and the sympathetic system. Pheochromocytoma.
Adrenal (cortex) insufficiency.
Primary hyperaldosteronism.
Secondary hyperaldosteronism.
Glucocorticoid hyperfunctional states.
Pathophysiological aspects of glucocorticoid therapy.
Abnormalities of parathyroid functions and calcium levels, their manifestations in teeth and bones.
Hypocalcemia, hypercalcemia.
Mechanisms and disturbances of bone remodeling. Osteoporosis, osteomalacia.
Pathophysiological aspects of the dental treatment of elderly patients.

Note: Oral exam on the basis of 3 questions from the list above.

Examiners

• Burzánné Dr. Pétervári Erika
• Dr. Balaskó Márta

Instructor / tutor of practices and seminars