Analytical Chemistry 2

Data

Official data in SubjectManager for the following academic year: 2020-2021

Course director

Number of hours/semester

lectures: 28 hours

practices: 42 hours

seminars: 0 hours

total of: 70 hours

Subject data

  • Code of subject: OPA-AN2-T
  • 5 kredit
  • Pharmacy
  • Basic modul
  • spring
Prerequisites:

OPA-AN1-T completed , OPA-AT1-T completed

Exam course:

yes

Course headcount limitations

min. 5 – max. 50

Topic

Within the frame of the theoretical and practical trainings of this subject students will study the quantitative approach of chemistry. This approach is crucial for the study of almost all fields of the pharmaceutical sciences such as pharmaceutical chemistry, pharmaceutical technology etc. Students have to learn and examine the theory and practice of analytical reactions, methods, rules and calculations.

Lectures

  • 1. Introduction to quantitative chemical analysis. The analytical process. The tools - Dr. Perjési Pál
  • 2. Introduction to quantitative chemical analysis. The analytical process. The tools. - Dr. Perjési Pál
  • 3. Quality assurance. Calibration methods. - Dr. Perjési Pál
  • 4. Quality assurance. Calibration methods. - Dr. Perjési Pál
  • 5. Chemical equilibrium - Dr. Perjési Pál
  • 6. Chemical equilibrium - Dr. Perjési Pál
  • 7. Acid-base titrations. Titration curve. Indication of equivalence point. - Dr. Perjési Pál
  • 8. Acid-base titrations. Titration curve. Indication of equivalence point. - Dr. Perjési Pál
  • 9. Neutralization analysis. Titration of strong acids and bases. - Dr. Perjési Pál
  • 10. Neutralization analysis. Titration of strong acids and bases. - Dr. Perjési Pál
  • 11. Neutralization analysis. Titration of weak acids and bases. - Dr. Perjési Pál
  • 12. Neutralization analysis. Titration of weak acids and bases. - Dr. Perjési Pál
  • 13. Neutralization analysis. Titration in non-aqueous solutions. - Dr. Perjési Pál
  • 14. Neutralization analysis. Titration in non-aqueous solutions. - Dr. Perjési Pál
  • 15. Statistics. The experimental error. - Dr. Perjési Pál
  • 16. Statistics. The experimental error. - Dr. Perjési Pál
  • 17. Complexometry I. - Dr. Perjési Pál
  • 18. Complexometry I. - Dr. Perjési Pál
  • 19. Complexometry II. - Dr. Perjési Pál
  • 20. Complexometry II. - Dr. Perjési Pál
  • 21. Precipitate titrations. - Dr. Perjési Pál
  • 22. Precipitate titrations. - Dr. Perjési Pál
  • 23. Redox titrations.Titration curve. Indication of equivalence point. - Dr. Perjési Pál
  • 24. Redox titrations.Titration curve. Indication of equivalence point. - Dr. Perjési Pál
  • 25. Redox titrations. Oxidimetry. - Dr. Perjési Pál
  • 26. Redox titrations. Oxidimetry. - Dr. Perjési Pál
  • 27. Redox titrations. Reductometry. - Dr. Perjési Pál
  • 28. Redox titrations. Reductometry. - Dr. Perjési Pál

Practices

  • 1. Laboratory safety and accident protection. The tools. Weighing.
  • 2. Laboratory safety and accident protection. The tools. Weighing.
  • 3. Laboratory safety and accident protection. The tools. Weighing.
  • 4. General introduction. Measurements. Calibration.
  • 5. General introduction. Measurements. Calibration.
  • 6. General introduction. Measurements. Calibration.
  • 7. Measurements. Calibration.
  • 8. Measurements. Calibration.
  • 9. Measurements. Calibration.
  • 10. Standardization of 0.1 M hydrochloric acid solution.
  • 11. Standardization of 0.1 M hydrochloric acid solution.
  • 12. Standardization of 0.1 M hydrochloric acid solution.
  • 13. Acid-base titrations II. Determination of borax (sodium tetraborate) by alkalimetry and acidimetry.
  • 14. Acid-base titrations II. Determination of borax (sodium tetraborate) by alkalimetry and acidimetry.
  • 15. Acid-base titrations II. Determination of borax (sodium tetraborate) by alkalimetry and acidimetry.
  • 16. Acid-base titrations II. Parallel determination of sodium hydroxide and sodium carbonate by Winkler's method.
  • 17. Acid-base titrations II. Parallel determination of sodium hydroxide and sodium carbonate by Winkler's method.
  • 18. Acid-base titrations II. Parallel determination of sodium hydroxide and sodium carbonate by Winkler's method.
  • 19. Acid-base titrations III. Parallel determination of sodium hydrogen carbonate and sodium carbonate by Warder's method. Determination of potassium acetate in glacial acetic acid (demonstration).
  • 20. Acid-base titrations III. Parallel determination of sodium hydrogen carbonate and sodium carbonate by Warder's method. Determination of potassium acetate in glacial acetic acid (demonstration).
  • 21. Acid-base titrations III. Parallel determination of sodium hydrogen carbonate and sodium carbonate by Warder's method. Determination of potassium acetate in glacial acetic acid (demonstration).
  • 22. Complexometry I.: Determination of calcium and magnesium ion sin the presence of each other.
  • 23. Complexometry I.: Determination of calcium and magnesium ion sin the presence of each other.
  • 24. Complexometry I.: Determination of calcium and magnesium ion sin the presence of each other.
  • 25. Complexometry II.: Determination of nickel (II) ions. Determination of aluminium ions by reverse titration.
  • 26. Complexometry II.: Determination of nickel (II) ions. Determination of aluminium ions by reverse titration.
  • 27. Complexometry II.: Determination of nickel (II) ions. Determination of aluminium ions by reverse titration.
  • 28. Precipitate formation titrations. - Argentometry. Determination of chloride ions by Volhard's and Mohr's methods.
  • 29. Precipitate formation titrations. - Argentometry. Determination of chloride ions by Volhard's and Mohr's methods.
  • 30. Precipitate formation titrations. - Argentometry. Determination of chloride ions by Volhard's and Mohr's methods.
  • 31. Redox titrations I. - Permanganometry. Standardization of 0.02 M potassium permanganate solution. Determination of calcium ions by reverse titration.
  • 32. Redox titrations I. - Permanganometry. Standardization of 0.02 M potassium permanganate solution. Determination of calcium ions by reverse titration.
  • 33. Redox titrations I. - Permanganometry. Standardization of 0.02 M potassium permanganate solution. Determination of calcium ions by reverse titration.
  • 34. Redox titrations II. - Permanganometry. Determination of hydrogen peroxide. Determination of iron (II) ions.
  • 35. Redox titrations II. - Permanganometry. Determination of hydrogen peroxide. Determination of iron (II) ions.
  • 36. Redox titrations II. - Permanganometry. Determination of hydrogen peroxide. Determination of iron (II) ions.
  • 37. Redox titrations III. - Iodometry. Standardization of 0.01 M sodium thiosulfate measuring solution. Determination of copper (II) ions.
  • 38. Redox titrations III. - Iodometry. Standardization of 0.01 M sodium thiosulfate measuring solution. Determination of copper (II) ions.
  • 39. Redox titrations III. - Iodometry. Standardization of 0.01 M sodium thiosulfate measuring solution. Determination of copper (II) ions.
  • 40. Redox titrations IV. - Iodometry. Determination of hydrogen peroxide. Determination of water by Karl-Fischer method.
  • 41. Redox titrations IV. - Iodometry. Determination of hydrogen peroxide. Determination of water by Karl-Fischer method.
  • 42. Redox titrations IV. - Iodometry. Determination of hydrogen peroxide. Determination of water by Karl-Fischer method.

Seminars

Reading material

Obligatory literature

Harris D.C.: Quantitative Chemical Analysis, 8th ed., W.H. Freeman and Co., New York, 2010

Literature developed by the Department

Laboratory handouts - describing details of the experiments.

Notes

Recommended literature

Conditions for acceptance of the semester

Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation is both the lectures and the practices is obligatory. Maximum three absences can be accepted both from lectures and practices. Two compulsory midterm tests (on the topics of the lectures and practices) will be written during the semester on the 7th and the 12th weeks. One of the test result should be above 60%. One re-take chance is allowed at the 14th weak of the semester. Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester.

Mid-term exams

Two compulsory midterm tests (on the topics of the lectures and practices) will be written during the semester on the 7th and the 12th weeks. One of the test results should be above 60%. One re-take chance is allowed at the 14th weak of the semester. Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgment of the semester.

Making up for missed classes

There is no opportunity to make up missed classes (lectures and practices).

Exam topics/questions

Oral exam covering the topics of Analytical Chemistry 1 and Analytical Chemistry 2. The list of questions of the final exam is available on the home page of the Institute.

Examiners

  • Dr. Huber Imre
  • Dr. Perjési Pál

Instructor / tutor of practices and seminars

  • Dr. Almási Attila
  • Dr. Kulcsár Győző Kornél
  • Dr. Rozmer Zsuzsanna