Pharmacopoeial Analysis 2 - practice

Data

Official data in SubjectManager for the following academic year: 2021-2022

Course director

Number of hours/semester

lectures: 0 hours

practices: 42 hours

seminars: 0 hours

total of: 42 hours

Subject data

  • Code of subject: OPA-L2G-T
  • 3 kredit
  • Pharmacy
  • Basic modul
  • spring
Prerequisites:

OPA-L1E-T completed , OPA-ALK-T completed

Course headcount limitations

min. 5 – max. 60

Topic

Within the frame of the theoretical and practical trainings of this subject students will study the quantitative approach of chemical analysis. This approach is crucial for the study of almost all fields of the pharmaceutical sciences such as pharmaceutical chemistry, pharmaceutical technology etc. Students have to learn and examine the theory and practice of the quantitative analytical reactions, methods, rules and calculations.

Lectures

Practices

  • 1. Laboratory safety and accident protection. The tools. Weighing.
  • 2. Laboratory safety and accident protection. The tools. Weighing.
  • 3. Laboratory safety and accident protection. The tools. Weighing.
  • 4. General introduction. Measurements. Calibration.
  • 5. General introduction. Measurements. Calibration.
  • 6. General introduction. Measurements. Calibration.
  • 7. Measurements. Calibration.
  • 8. Measurements. Calibration.
  • 9. Measurements. Calibration.
  • 10. Standardization of 0.1 M hydrochloric acid solution.
  • 11. Standardization of 0.1 M hydrochloric acid solution.
  • 12. Standardization of 0.1 M hydrochloric acid solution.
  • 13. Acid-base titrations II. Determination of borax (sodium tetraborate) by alkalimetry and acidimetry.
  • 14. Acid-base titrations II. Determination of borax (sodium tetraborate) by alkalimetry and acidimetry.
  • 15. Acid-base titrations II. Determination of borax (sodium tetraborate) by alkalimetry and acidimetry.
  • 16. Acid-base titrations II. Parallel determination of sodium hydroxide and sodium carbonate by Winkler's method.
  • 17. Acid-base titrations II. Parallel determination of sodium hydroxide and sodium carbonate by Winkler's method.
  • 18. Acid-base titrations II. Parallel determination of sodium hydroxide and sodium carbonate by Winkler's method.
  • 19. Acid-base titrations III. Parallel determination of sodium hydrogen carbonate and sodium carbonate by Warder's method. Determination of potassium acetate in glacial acetic acid (demonstration).
  • 20. Acid-base titrations III. Parallel determination of sodium hydrogen carbonate and sodium carbonate by Warder's method. Determination of potassium acetate in glacial acetic acid (demonstration).
  • 21. Acid-base titrations III. Parallel determination of sodium hydrogen carbonate and sodium carbonate by Warder's method. Determination of potassium acetate in glacial acetic acid (demonstration).
  • 22. Complexometry I.: Determination of calcium and magnesium ion sin the presence of each other.
  • 23. Complexometry I.: Determination of calcium and magnesium ion sin the presence of each other.
  • 24. Complexometry I.: Determination of calcium and magnesium ion sin the presence of each other.
  • 25. Complexometry II.: Determination of nickel (II) ions. Determination of aluminium ions by reverse titration.
  • 26. Complexometry II.: Determination of nickel (II) ions. Determination of aluminium ions by reverse titration.
  • 27. Complexometry II.: Determination of nickel (II) ions. Determination of aluminium ions by reverse titration.
  • 28. Precipitate formation titrations. - Argentometry. Determination of chloride ions by Volhard's and Mohr's methods.
  • 29. Precipitate formation titrations. - Argentometry. Determination of chloride ions by Volhard's and Mohr's methods.
  • 30. Precipitate formation titrations. - Argentometry. Determination of chloride ions by Volhard's and Mohr's methods.
  • 31. Redox titrations I. - Permanganometry. Standardization of 0.02 M potassium permanganate solution. Determination of calcium ions by reverse titration.
  • 32. Redox titrations I. - Permanganometry. Standardization of 0.02 M potassium permanganate solution. Determination of calcium ions by reverse titration.
  • 33. Redox titrations I. - Permanganometry. Standardization of 0.02 M potassium permanganate solution. Determination of calcium ions by reverse titration.
  • 34. Redox titrations II. - Permanganometry. Determination of hydrogen peroxide. Determination of iron (II) ions.
  • 35. Redox titrations II. - Permanganometry. Determination of hydrogen peroxide. Determination of iron (II) ions.
  • 36. Redox titrations II. - Permanganometry. Determination of hydrogen peroxide. Determination of iron (II) ions.
  • 37. Redox titrations III. - Iodometry. Standardization of 0.01 M sodium thiosulfate measuring solution. Determination of copper (II) ions.
  • 38. Redox titrations III. - Iodometry. Standardization of 0.01 M sodium thiosulfate measuring solution. Determination of copper (II) ions.
  • 39. Redox titrations III. - Iodometry. Standardization of 0.01 M sodium thiosulfate measuring solution. Determination of copper (II) ions.
  • 40. Redox titrations IV. - Iodometry. Determination of hydrogen peroxide. Determination of water by Karl-Fischer method.
  • 41. Redox titrations IV. - Iodometry. Determination of hydrogen peroxide. Determination of water by Karl-Fischer method.
  • 42. Redox titrations IV. - Iodometry. Determination of hydrogen peroxide. Determination of water by Karl-Fischer method.

Seminars

Reading material

Obligatory literature

Harris D.C.: Quantitative Chemical Analysis, 8th ed., W.H. Freeman and Co., New York, 2010.

Literature developed by the Department

Laboratory handouts - describing details of the experiments.

Notes

Recommended literature

Conditions for acceptance of the semester

Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation in the practices of the course is obligatory. Maximum 3 absences are allowed. Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester.

Mid-term exams

Making up for missed classes

There is no opportunity to make up missed classes (lectures and practices).

Exam topics/questions

Examiners

Instructor / tutor of practices and seminars

  • Dr. Fatemeh KENARI
  • Dr. Almási Attila
  • Dr. Kulcsár Győző Kornél
  • Dr. Rozmer Zsuzsanna