Pharmaceutical Nanotechnology

Data

Official data in SubjectManager for the following academic year: 2022-2023

Course director

  • Dr. Aleksandar SECENJI

    senior research fellow,
    Institute of Pharmaceutical Technology and Biopharmacy

Number of hours/semester

lectures: 28 hours

practices: 0 hours

seminars: 0 hours

total of: 28 hours

Subject data

  • Code of subject: OBF-PNT-T
  • 2 kredit
  • Biotechnology MSc
  • Optional modul
  • spring
Prerequisites:

-

Course headcount limitations

min. 5 – max. 50

Available as Campus course for 2 fő számára. Campus-karok: ÁOK GYTK TTK

Topic

Nanotechnology is a multidisciplinary discipline, which is the approach of the production of materials, structures, and systems, in which the material is handled and produced in nanometers i.e. in a billionth of a meter. Pharmaceutical nanotechnology is the application of nanotechnology in the pharmaceutical industry in life and health sciences and is base for the development of nanostructured modern drug delivery systems for therapeutic purposes as well as advanced diagnostic biosensors dealing with early detection of diseases
The aim of the course is to provide a comprehensive picture of the application of nanotechnology in drug development and pharmaceuticals. A brief introduction to the history, role, and impact of nanotechnology on state-of-the-art technologies. The properties of specific physicochemical properties of nanomaterials can be explained by the well-known thermodynamic principles. Because of the small size, the surface and the quantum effects play a prominent role, the theoretical basis of which is presented. Hereinafter, the classification of nanoscale medicines and their detailed presentation will be presented.

Lectures

  • 1. Introduction to Nanotechnology - Dr. Secenji Aleksandar
  • 2. Introduction to Nanotechnology - Dr. Secenji Aleksandar
  • 3. Theoretical basics of nanotechnology - Dr. Secenji Aleksandar
  • 4. Theoretical basics of nanotechnology - Dr. Secenji Aleksandar
  • 5. Drug nanocarriers classification - Dr. Secenji Aleksandar
  • 6. Drug nanocarriers classification - Dr. Secenji Aleksandar
  • 7. Inorganic nanostructures - Dr. Secenji Aleksandar
  • 8. Inorganic nanostructures - Dr. Secenji Aleksandar
  • 9. Organic nanostructures - Dr. Secenji Aleksandar
  • 10. Organic nanostructures - Dr. Secenji Aleksandar
  • 11. Pharmaceutical nanocrystals - Dr. Secenji Aleksandar
  • 12. Pharmaceutical nanocrystals - Dr. Secenji Aleksandar
  • 13. Matrix Systems - Dr. Secenji Aleksandar
  • 14. Matrix Systems - Dr. Secenji Aleksandar
  • 15. Porous systems - Dr. Secenji Aleksandar
  • 16. Porous systems - Dr. Secenji Aleksandar
  • 17. Binding, filling, trapping and releasing the drug from nanostructures - Dr. Secenji Aleksandar
  • 18. Binding, filling, trapping and releasing the drug from nanostructures - Dr. Secenji Aleksandar
  • 19. Hydrophobic drugs - Dr. Secenji Aleksandar
  • 20. Hydrophobic drug - Dr. Secenji Aleksandar
  • 21. Hydrophilic drugs - Dr. Secenji Aleksandar
  • 22. Hydrophilic drugs - Dr. Secenji Aleksandar
  • 23. Makromolecular drug carriers - Dr. Secenji Aleksandar
  • 24. Makromolecular drug carriers - Dr. Secenji Aleksandar
  • 25. Vesicular drug delivery systems - Dr. Secenji Aleksandar
  • 26. Vesicular drug delivery systems - Dr. Secenji Aleksandar
  • 27. Nano Emulsions, Pickering Emulsions - Dr. Secenji Aleksandar
  • 28. Nano Emulsions Pickering Emulsions - Dr. Secenji Aleksandar

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

Notes

Recommended literature

1. Nanotechnology in Drug Delivery, Melgardt M. de Villiers, Pornanong Aramwit, Glen S. Kwon, Springer, DOI: 10.1007/978-0-387-77667-5
2. Pharmaceutical Nanotechnology: Fundamentals and Practical Applications, Costas Demetzos, ADIS, DOI 10.1007/978-981-10-0791-0
3. Pharmaceutical Nanotechnology: Innovation and Production, Jean Cornier, Andrew Owen, Arno Kwade, and Marcel Van de Voorde, WILEY-VCH, Print ISBN: 978-3-527-34054-5, ePDF ISBN: 978-3-527-80067-4

Conditions for acceptance of the semester

Maximum of 25 % absence allowed

Mid-term exams

1 written test

Making up for missed classes

not needed

Exam topics/questions

1. Introduction to Nanotechnology
2. Theoretical basics of nanotechnology
3. Drug nanocarriers classification
4. Inorganic nanostructures
5. Organic nanostructures
6. Pharmaceutical nanocrystals
7. Matrix Systems
8. Porous systems
9. Binding, filling, trapping and releasing the drug from nanostructures
10. Hydrophobic drug
11. Hydrophilic drugs
12. Makromolecular drug carriers
13. Vesicular drug delivery systems
14. Nano Emulsions Pickering Emulsions

Examiners

Instructor / tutor of practices and seminars