Bone Pathology

Data

Official data in SubjectManager for the following academic year: 2019-2020

Course director

  • Dr. László MÁRK

    associate professor,
    Department of Biochemistry and Medical Chemistry

Number of hours/semester

lectures: 22 hours

practices: 0 hours

seminars: 0 hours

total of: 22 hours

Subject data

  • Code of subject: OSF-PCS-T
  • 2 kredit
  • Dentistry
  • Optional modul
  • spring
Prerequisites:

-

Course headcount limitations

min. 3 – max. 50

Topic

The course gives an overall review about the observable pathological alterations of the human remains with their diagnostic possibilities as well as their interpretation.
Topics:
Chemical composition of human bone tissue.
Sex determination techniques.
Life determination.
Congenital alterations.
Traumatic morphology.
Trepanations.
Mycobacterial infections.
Tuberculosis.
Lepra
Syphilis.
The Pest.
Bone tumors, osteocarcinoma.
Joint diseases.
Oral paleopathology.
Molecular biomarker discovery.
Evolution of human pathogenes.
Evolution of Mycobacterium.

Lectures

  • 1. Introduction - Dr. Márk László
  • 2. The paleopathology, an interdisciplinary science - Dr. Márk László
  • 3. Chemical composition and biochemistry of the bone tissue - Dr. Márk László
  • 4. Chemical composition and biochemistry of the bone tissue - Dr. Márk László
  • 5. Sex determination techniques - Dr. Márk László
  • 6. Lifetime determination - Dr. Márk László
  • 7. Congenital alterations. Trauma - Dr. Márk László
  • 8. Trepanations - Dr. Márk László
  • 9. Tuberculosis - Dr. Márk László
  • 10. Tuberculosis - Dr. Márk László
  • 11. Lepra - Dr. Márk László
  • 12. Lepra - Dr. Márk László
  • 13. Syphilis - Dr. Márk László
  • 14. Syphilis - Dr. Márk László
  • 15. The Pest - Dr. Márk László
  • 16. The Pest - Dr. Márk László
  • 17. Osteo-necrotic alterations, dystrophies - Dr. Márk László
  • 18. Osteocarcinoma, bone tumors - Dr. Márk László
  • 19. Joint diseases - Dr. Márk László
  • 20. Oral paleopathology - Dr. Márk László
  • 21. Determination of molecular biomarkers - Dr. Márk László
  • 22. Paleoproteomics. Evolution of the human pathogenes - Dr. Márk László

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

Lecture slides and notes.

Notes

Recommended literature

A.C. Aufderheide: Cambrige Encyclopedia of Human Paleopathology, 1998
Human Paleopathology Eds. Ortner, Aufderheide. 2001.
Palfi et al: Tuberculosis Past and Present, 1999

Conditions for acceptance of the semester

Written exam. Max. absences: 20%.

Mid-term exams

Not possible

Making up for missed classes

Not possible.

Exam topics/questions

Chemical composition of human bone tissue.
Sex determination techniques.
Life determination.
Congenital alterations.
Traumatic morphology.
Trepanations.
Mycobacterial infections.
Tuberculosis.
Lepra.
Syphilis.
The Pest.
Bone tumors, osteocarcinoma.
Joint diseases.
Oral paleopathology.
Molecular biomarker discovery.
Evolution of human pathogenes.
Evolution of Mycobacterium.

Examiners

Instructor / tutor of practices and seminars