Biochemistry for Dentistry Students

Data

Official data in SubjectManager for the following academic year: 2019-2020

Course director

  • Dr. Péter JAKUS

    assistant professor,
    Department of Biochemistry and Medical Chemistry

Number of hours/semester

lectures: 42 hours

practices: 0 hours

seminars: 0 hours

total of: 42 hours

Subject data

  • Code of subject: OSA-BKD-T
  • 3 kredit
  • Dentistry
  • Basic modul
  • autumn
Prerequisites:

OSA-ORF-T completed , OSA-BEF-T completed

Exam course:

yes

Course headcount limitations

min. 1 – max. 200

Topic

The subject gives an overview of the molecular processes occurring in living organisms from two major aspects. On the one hand, following the subject -Introduction to Biochemistry&-, it describes the metabolism of the four major types of biomolecules (carbohydrates, lipids, amino ac ids/proteins and nucleotides /nucleic acids) along with the indirect enzymatic regulation of
these processes. On the other hand, built on the subject -Molecular Cell Biology&-, accounts for the molecular processes responsible for the transmission of information within the living organisms from molecular biological (DNA-RNA-protein-metabolite) as well as hormonal point of view. The subject lies down the foundations of the subjects Medical Biochemistry, Pharmacology and Clinical Chemistry.

Lectures

  • 1. Introduction - Dr. Jakus Péter Balázs
  • 2. The pentose phosphate pathway - Dr. Veres Balázs
  • 3. Gluconeogenesis in animal cells - Dr. Jakus Péter Balázs
  • 4. Glycogen synthesis and degradation - Dr. Bognár Zita
  • 5. Regulation of glycogen synthesis and degradation - Dr. Bognár Zita
  • 6. Regulation and disorders of carbohydrate metabolism - Dr. Tapodi Antal
  • 7. Fatty acid synthesis (with elongation and desaturation) - Dr. Tapodi Antal
  • 8. Synthesis of complex lipids - Dr. Gallyas Ferenc
  • 9. Structure and biological activities of steroids - Dr. Gallyas Ferenc
  • 10. Synthesis of cholesterol and ketone bodies - Dr. Gallyas Ferenc
  • 11. Regulation and disorders of lipid metabolism - Dr. Gallyas Ferenc
  • 12. Amino acid metabolism; the fate of the amino group - Dr. Debreceni Balázs
  • 13. Urea cycle - Dr. Debreceni Balázs
  • 14. Amino acid metabolism; the fate of the carbon skeleton - Dr. Debreceni Balázs
  • 15. Synthesis of non-essential amino acids - Dr. Debreceni Balázs
  • 16. Enzymopathies of amino acid metabolism - Dr. Debreceni Balázs
  • 17. Synthesis of biologically active molecules from amino acids - Dr. Debreceni Balázs
  • 18. Synthesis of purine and pyrimidine nucleotides - Dr. Jakus Péter Balázs
  • 19. Degradation of purine and pyrimidine nucleotides - Dr. Jakus Péter Balázs
  • 20. Genes and chromosomes - Dr. Jakus Péter Balázs
  • 21. DNA replication - Dr. Jakus Péter Balázs
  • 22. DNA repair - Dr. Jakus Péter Balázs
  • 23. RNA metabolism 1 - Dr. Veres Balázs
  • 24. RNA metabolism 2 - Dr. Veres Balázs
  • 25. Short RNA molecules - Dr. Veres Balázs
  • 26. Retroviruses - Dr. Veres Balázs
  • 27. Protein synthesis 1. Participants and mechanism - Dr. Jakus Péter Balázs
  • 28. Protein synthesis 2. Regulation, posttranslational modifications - Dr. Berente Zoltán
  • 29. Protein folding, chaperones - Dr. Berente Zoltán
  • 30. Protein targeting and vesicular transport of proteins - Dr. Berente Zoltán
  • 31. Intracellular proteolysis - Dr. Jakus Péter Balázs
  • 32. Regulation of gene expression 1 - Dr. Jakus Péter Balázs
  • 33. Regulation of gene expression 2 - Dr. Sümegi Balázs
  • 34. Mitochondrial protein synthesis, mitochondrial genome - Dr. Sümegi Balázs
  • 35. Recombinant DNA technologies - Dr. Jakus Péter Balázs
  • 36. Hormones 1 - Dr. Tapodi Antal
  • 37. Hormones 2 - Dr. Tapodi Antal
  • 38. Cell signalling and kinases I - Dr. Veres Balázs
  • 39. Cell signalling and kinases II - Dr. Jakus Péter Balázs
  • 40. Cell signalling, CO and NO as signals, transcription factors - Dr. Jakus Péter Balázs
  • 41. Water soluble vitamins - Dr. Jakus Péter Balázs
  • 42. Lipid soluble vitamins - Dr. Jakus Péter Balázs

Practices

Seminars

Reading material

Obligatory literature

Nelson, Cox: Lehninger Principles of Biochemistry, 6th edition, W.H. Freeman, 2013

Literature developed by the Department

Notes

Nagy V.: Experiments is Med. Chem. lab manual, 2017
Nagy V.: Introduction to biochemistry lab manual 2017

Recommended literature

Berg, Tymoczko, Stryer: Biochemistry, 7th edition, W.H. Freeman, 2012.
Devlin: Textbook of Biochemistry with Clinical Correlations 7th edition, Wiley, 2010.

Conditions for acceptance of the semester

Maximum of 15 % absence allowed

Mid-term exams

It is obligatory to visit the lectures.

Making up for missed classes

Non

Exam topics/questions

The exam based on the lectures and labs of the previous semesters and the lectures of the actual semester.
After entering into the website of the UNI: http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Examiners

  • Dr. Bognár Zita
  • Dr. Jakus Péter Balázs
  • Dr. Takátsy Anikó
  • Dr. Tapodi Antal

Instructor / tutor of practices and seminars