Introduction to Biochemistry for Dentistry Students

Data

Official data in SubjectManager for the following academic year: 2020-2021

Course director

Number of hours/semester

lectures: 28 hours

practices: 14 hours

seminars: 0 hours

total of: 42 hours

Subject data

  • Code of subject: OSA-BEF-T
  • 3 kredit
  • Dentistry
  • Basic modul
  • spring
Prerequisites:

-

Exam course:

yes

Course headcount limitations

min. 1 – max. 96

Topic

Introduction to Biochemistry includes the topics of organic and bio-organic chemistry along with basic biochemistry which are necessary for dentistry students. It deals with the structure, chemistry, and cellular metabolism of essential biomolecules like proteins, carbohydrates and lipids. The purpose of practices is to consider the chemistry of bio-compounds. Curriculum of Introduction to Biochemistry contains the basic knowledge that is necessary to understand cell biology, physiology, pharmacology and biochemistry.

Lectures

  • 1. Introduction - Dr. Jakus Péter Balázs
  • 2. Nucleosides, nucleotides, nucleic acids - Dr. Takátsy Anikó
  • 3. Nucleotide coenzymes, bioenergetics - Dr. Takátsy Anikó
  • 4. Amino acids, peptides - Dr. Takátsy Anikó
  • 5. Protein structure and function - Dr. Takátsy Anikó
  • 6. Basics of enzyme kinetics - Dr. Takátsy Anikó
  • 7. Regulation and inhibition of enzymatic activity, isoenzymes - Dr. Takátsy Anikó
  • 8. Composition of simple and complex lipids - Dr. Takátsy Anikó
  • 9. Characterization of biological membranes - Dr. Takátsy Anikó
  • 10. Membrane transports - Dr. Takátsy Anikó
  • 11. Structure and reactivity of carbohydrates - Dr. Takátsy Anikó
  • 12. Medically relevant di-, oligo and polysaccharides - Dr. Takátsy Anikó
  • 13. Biochemical processes (overview) - Dr. Takátsy Anikó
  • 14. Hemoglobin, oxygen transport - Dr. Takátsy Anikó
  • 15. Reactions of glycolysis - Dr. Jakus Péter Balázs
  • 16. Regulation of glycolysis - Dr. Jakus Péter Balázs
  • 17. Metabolic pathways linked to glycolysis - Dr. Jakus Péter Balázs
  • 18. Reactions of TCA cycle (PDC included) - Dr. Jakus Péter Balázs
  • 19. Regulation of TCA cycle - Dr. Jakus Péter Balázs
  • 20. Fatty acid oxidation - Dr. Jakus Péter Balázs
  • 21. Respiratory chain and its inhibition - Dr. Jakus Péter Balázs
  • 22. ATP synthesis - Dr. Jakus Péter Balázs
  • 23. Regulation of respiratory chain - Dr. Jakus Péter Balázs
  • 24. Mitochondrial transport processes, shuttles - Dr. Takátsy Anikó
  • 25. Ketonbodies - Dr. Takátsy Anikó
  • 26. Biologically relevant lipids (prostaglandins, terpenoids) - Dr. Takátsy Anikó
  • 27. Biologically relevant lipids (steroids) - Dr. Lóránd Tamás
  • 28. Carbonic acid derivatives and medicaments - Dr. Lóránd Tamás

Practices

  • 1. Stereochemistry, molecule model exercises, -practice
  • 2. Stereochemistry, molecule model exercises, -practice
  • 3. Organic Chemistry, - practice
  • 4. Organic Chemistry, - practice
  • 5. Proteins, nucleotides, coenzymes, enzymes, - practice
  • 6. Proteins, nucleotides, coenzymes, enzymes, - practice
  • 7. Enzymes, metabolism I. - practice
  • 8. Enzymes, metabolism I. - practice
  • 9. Investigation of Carbohydrates , metabolism II. - practice
  • 10. Investigation of Carbohydrates , metabolism II. - practice
  • 11. Investigation of Carbohydrates , metabolism III. - practice
  • 12. Investigation of Carbohydrates , metabolism III. - practice
  • 13. Investigation of Lipids, metabolism IV. - practice
  • 14. Investigation of Lipids, metabolism IV. - practice

Seminars

Reading material

Obligatory literature

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Literature developed by the Department

Notes

Nagy V., Agócs A. :Introduction to biochemistry lab manual 2017/18http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Recommended literature

Nelson, Cox: Lehninger Principles of Biochemistry, 5th ed., W.H. Freeman, 2008
http://bcs.whfreeman.com/lehninger5e

Berg, Tymoczko, Stryer: Biochemistry, 7th ed.
http://bcs.whfreeman.com/berg7e

Conditions for acceptance of the semester

Maximum of 15 % absence allowed

Mid-term exams

There are lab practices at every EVEN NUMBERED EDUCATIONAL weeks (2-4-6-8-10-12-14). There are short tests from week 2 till 14. The lab is beginning with a short test (time is 6 minutes; 7 occasions; max. 14 points). Requirement for acceptance is writing 6 test out of 7 possibility, and to gain at least 7 points from the maximum 14 points.
There is no possibilities to write a short test if delaying is over 5 minutes. No more than 10 minutes delay is accepted, over of it, it is an absence. No more than 1 absence is allowed from the 7 lab occasions (15%).
It is obligatory to write lab-notes. Result of the short test is acknowledged only if the lab-notes of the practice is accepted by the lab instructor. The exam is based on the topic of the lectures and labs. The lectures are identical with the General Medicine program. The exam conditions are on the website of the department. (http://aok.pte.hu/en/egyseg/oktatasianyagok/20)

Making up for missed classes

There is no possibility to make up of the lab practices.

Exam topics/questions

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Examiners

  • Dr. Bognár Zita
  • Dr. Bóna Ágnes
  • Dr. Jakus Péter Balázs

Instructor / tutor of practices and seminars

  • Dr. Jakus Péter Balázs