Data
Official data in SubjectManager for the following academic year: 2020-2021
Course director
-
Dr. Zoltán BERENTE
associate professor,
Department of Biochemistry and Medical Chemistry -
Number of hours/semester
lectures: 0 hours
practices: 0 hours
seminars: 0 hours
total of: 0 hours
Subject data
- Code of subject: OXF-MMG-r-T
- 1 kredit
- Pharmacy
- Optional modul
- spring
OHO-GE2-T parallel , OHA-M1E-T parallel
Course headcount limitations
min. 3 – max. 20
Topic
The course provides an insight into the process of drug development through examples that involve nuclear magnetic resonance as an analytical tool. The method is extensively applied at numerous different points of the process, due to its versatility.
The course will discuss, after a brief theoretical introduction, the study of structure determination and structure-activity relationship of drug candidate molecules. In the second phase the course will discuss some (mostly in vivo) applications used for the investigation of the efficacy of drug candidates in various animal models.
Lectures
Practices
Seminars
Reading material
Obligatory literature
None
Literature developed by the Department
See Neptun Meet Street
Notes
See Neptun Meet Street
Recommended literature
R. A. de Graaf: In vivo NMR Spectroscopy, Wiley, 1998
N. Beckman: In vivo MR Techniques in Drug Discovery and Development, Taylor and Francis, 2006
http://cis.rit.edu/htbooks/nmr
http://cis.rit.edu/htbooks/mri
http://www.imaios.com/en/e-Courses/e-MRI
http://www.magnetic-resonance.org/
http://eprints.drcmr.dk/37/1/MRI_English_a4.pdf
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Presentation of a home project is required.
Making up for missed classes
On the judgement of the course director.
Exam topics/questions
-