Data
Official data in SubjectManager for the following academic year: 2020-2021
Course director
-
Dr. Péter JAKUS
assistant professor,
Department of Biochemistry and Medical Chemistry -
Number of hours/semester
lectures: 24 hours
practices: 0 hours
seminars: 0 hours
total of: 24 hours
Subject data
- Code of subject: OSF-BK5-T
- 2 kredit
- Dentistry
- Optional modul
- autumn
OSA-BEF-T completed , OSA-BKD-T parallel
Course headcount limitations
min. 1 – max. 100
Topic
The goal of the current subject is preparing dentistry and medical students for the final exam (in Chemistry and Biochemistry). The major goal of the subject is to offer dentistry students - mainly who began their studies in 2016** - an integrative view of necessary knowledge in general, inorganic and organic chemistry, and biochemistry. The course highlights the relationships between topics covered by subjects 'Chemistry for Dentistry Students', 'Introduction to Biochemistry for Dentistry Students' and 'Biochemistry for Dentistry Students'. The course gives opportunity for both dentistry and medical students to raise questions and practice problem solving. The program also covers integrative regulation and relationships of metabolism.
Lectures
- 1. From Le'Chatelier to homeostasis. Osmolarity, pH in biochemistry. - Dr. Jakus Péter Balázs
- 2. From electron configuration to acidic strength; Buffer systems; From galvanic to mitochondria. Chemical properties of biomolecules. - Dr. Jakus Péter Balázs
- 3. From order to disorder. Why can life exist in the universe? Illustrative thermodynamics. - Dr. Jakus Péter Balázs
- 4. From reaction rate to enzyme activity. From enzyme inhibition to medication therapy. - Dr. Jakus Péter Balázs
- 5. Bioactive compounds. Relationship between structure and effect. - Dr. Jakus Péter Balázs
- 6. Organic Chemistry, reactions: From the test tube to the cell to the dentures. - Dr. Jakus Péter Balázs
- 7. "Successful Hunting I.": From glyceraldehyde to carbohydrate degradation. - Dr. Jakus Péter Balázs
- 8. "Successful Hunting II": Store. Glycogen metabolism, glycogen metabolism regulation. Lipid storage, protein synthesis. - Dr. Jakus Péter Balázs
- 9. "Successful Hunting III". Glucose in the cytoplasm maze. Aspects of regulating carbohydrate metabolism. - Dr. Bognár Zita
- 10. Hungaricums: Citrate cycle, "pálinka". Fatty liver. Control the citrate circle. - Dr. Bognár Zita
- 11. "Hunting": Jogging better than sprinting? Lipid degradation B oxidation. Misconceptions about muscle fever. - Dr. Bognár Zita
- 12. "And when we're not hunting": From carbohydrates to fatty acids to obesity and arteriosclerosis. - Dr. Bognár Zita
- 13. Carbohydrates: From glyceraldehyde to carbohydrate degradation. Aspects of regulating carbohydrate metabolism. - Dr. Bognár Zita
- 14. Aspects of fat metabolism regulation. - Dr. Bognár Zita
- 15. Respiratory chain and associated reactions. Mitochondrial transport processes and ATP synthesis. - Dr. Debreceni Balázs
- 16. Biochemical Mathematics: How Many ATPs Are Created When Degrading Some Molecules? - Dr. Debreceni Balázs
- 17. Proteins: From glycine through protein function to urea. Importance of nucleic acid metabolism. - Dr. Debreceni Balázs
- 18. Importance of nucleic acid metabolism. Metabolic Diseases. - Dr. Debreceni Balázs
- 19. Towards future biochemistry: new RNA and DNA mechanisms, their regulation. - Dr. Debreceni Balázs
- 20. Genetically Modified New World: PCR, Cloning, CRISPR. - Dr. Debreceni Balázs
- 21. "Telecommunications" in the cell: signaling pathways. - Dr. Debreceni Balázs
- 22. Through hormones to gene expression. - Dr. Debreceni Balázs
- 23. Sample Test. - Dr. Debreceni Balázs
- 24. Disscussion of the sample test. - Dr. Debreceni Balázs
Practices
Seminars
Reading material
Obligatory literature
Nelson, Cox: Lehninger Principles of Biochemistry, 6th edition, W.H. Freeman, 2013
Literature developed by the Department
Notes
Nagy V.: Experiments is Med. Chem. lab manual, 2017
Nagy V.: Introduction to Biochemistry. lab manual, 2017
Recommended literature
Hein, Pattison: Introduction to General, Organic and Biochemistry. Wiley, 2015
Berg, Tymoczko, Stryer: Biochemistry, 7th edition, W.H. Freeman, 2012.
Devlin: Textbook of Biochemistry with Clinical Correlations 7th edition, Wiley, 2010.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Midterm test at the 10th week.
Making up for missed classes
None
Exam topics/questions
http://aok.pte.hu/en/egyseg/index/20