Biochemistry for Dentistry Students

Data

Official data in SubjectManager for the following academic year: 2022-2023

Topic

The subject gives an overview of the molecular processes occurring in living organisms from two major aspects. On the one hand, following the subject -Introduction to Biochemistry, it describes the metabolism of the four major types of biomolecules (carbohydrates, lipids, amino ac ids/proteins and nucleotides /nucleic acids) along with the indirect enzymatic regulation of
these processes. On the other hand, built on the subject -Molecular Cell Biology, accounts for the molecular processes responsible for the transmission of information within the living organisms from molecular biological (DNA-RNA-protein-metabolite) as well as hormonal point of view. The subject lies down the foundations of the Pharmacology and Clinical Chemistry.

Lectures

• 1. Introduction - Dr. Debreceni Balázs
• 2. Biochemical processes (overview) - Dr. Veres Balázs
• 3. Reactions of glycolysis - Dr. Agócs Attila
• 4. Regulation of glycolysis - Dr. Agócs Attila
• 5. Metabolic pathways linked to glycolysis - Dr. Kovács Krisztina
• 6. Pentose phosphate pathway - Dr. Kovács Krisztina
• 7. Reactions of TCA cycle (PDC included) - Dr. Jávor-Hocsák Enikő
• 8. Regulation of TCA cycle - Dr. Takátsy Anikó
• 9. Fatty acid oxidation - Dr. Kovács Krisztina
• 10. Ketonbodies - Dr. Kovács Krisztina
• 11. Respiratory chain and its inhibition - Dr. Takátsy Anikó
• 12. ATP synthesis - Dr. Takátsy Anikó
• 13. Mitochondrial transport processes, shuttles - Dr. Takátsy Anikó
• 14. Gluconeogenesis - Dr. Takátsy Anikó
• 15. Glycogen synthesis and degradation - Dr. Veres Balázs
• 16. Regulation of glycogen metabolism - Dr. Veres Balázs
• 17. Regulation of carbohydrate metabolism - Dr. Radnai Balázs
• 18. Fatty acid synthesis - Dr. Radnai Balázs
• 19. Synthesis of complex lipids - Dr. Radnai Balázs
• 20. Cholesterol and lipoproteins - Dr. Radnai Balázs
• 21. Regulation of lipid metabolism - Dr. Radnai Balázs
• 22. Amino acid metabolism: the fate of amino group - Nagyné Dr. Kiss Gyöngyi
• 23. Urea cycle - Dr. Fekete Katalin
• 24. Amino acid metabolism: the fate of carbon skeleton - Dr. Debreceni Balázs
• 25. Synthesis of non-essential amino acids - Dr. Debreceni Balázs
• 26. Enzymopathies in amino acid metabolism - Dr. Debreceni Balázs
• 27. Biologically active compounds - Dr. Debreceni Balázs
• 28. Synthesis of purin and pyrimidin nucleotides - Dr. Bognár Zita
• 29. Degradation of purin and pyrimidin nucleotides - Dr. Bognár Zita
• 30. Protein -DNA interactions - Dr. Tapodi Antal
• 31. Regulation of gene expression - Dr. Tapodi Antal
• 32. Small RNAs - Dr. Tapodi Antal
• 33. Retroviruses - Dr. Tapodi Antal
• 34. Folding, PTM - Dr. Berente Zoltán
• 35. Protein targeting, degradation - Dr. Berente Zoltán
• 36. Hormones 1 - Dr. Jakus Péter Balázs
• 37. Hormones 2 - Dr. Jakus Péter Balázs
• 38. Signal transduction I. - Dr. Gallyas Ferenc
• 39. Signal transduction II. - Dr. Gallyas Ferenc
• 40. Signal transduction III. - Dr. Gallyas Ferenc
• 41. Water soluble vitamins - Dr. Antus Csenge Petra
• 42. Fat soluble vitamins - Dr. Jávor-Hocsák Enikő

Practices

Seminars

Reading material

Obligatory literature

Nelson, Cox: Lehninger Principles of Biochemistry, 6th edition, W.H. Freeman, 2013

Literature developed by the Department

www.aok.pte.hu

Notes

www.aok.pte.hu

Recommended literature

Berg, Tymoczko, Stryer: Biochemistry, 7th edition, W.H. Freeman, 2012.
Devlin: Textbook of Biochemistry with Clinical Correlations 7th edition, Wiley, 2010.

Conditions for acceptance of the semester

Maximum of 15 % absence allowed

Mid-term exams

It is obligatory to visit the lectures.

Making up for missed classes

Non

Exam topics/questions

The exam based on the lectures and labs of the previous semesters and the lectures of the actual semester.
After entering into the website of the UNI: http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Examiners

• Dr. Bognár Zita
• Dr. Debreceni Balázs

Instructor / tutor of practices and seminars