Chemistry for Dentistry Students

Data

Official data in SubjectManager for the following academic year: 2022-2023

Topic

Medical chemistry includes the topics of general chemistry which are necessary for medical students. It deals also with the chemistry of organic functional groups in concise way. Majority of the curriculum deals with the bioorganic chemistry, which means the chemistry and descriptive biochemistry of biomolecules. The purpose of practices is to study some analytical chemistry and the knowledge of materials. Curriculum of medical chemistry contains the basic knowledge that is necessary to understand biochemistry.

Lectures

• 1. Introduction to Medical Chemistry - Dr. Gallyas Ferenc
• 2. Structure of matter (atoms, ions, molecules, radicals) - Dr. Nagy Veronika
• 3. Intrduction to inorganic chemistry. Oxides, oxoacids, hydroxides, salts - Dr. Nagy Veronika
• 4. Molecular geometry, polarity, molecular interactions - Dr. Nagy Veronika
• 5. Introduction to organic chemistry. Nomenclatute, functional groups, Reaction types - Dr. Nagy Veronika
• 6. States of matter, gas laws. - Dr. Takátsy Anikó
• 7. Water and aqueous solutions. Concentration units. Colligative properties of dilute solutions. - Dr. Takátsy Anikó
• 8. Osmosis, composition of biofluids - Dr. Berente Zoltán
• 9. Equilibrium, the law of mass action, Le Chatelier principle - Dr. Takátsy Anikó
• 10. Role of electrolytes in living organisms, solubilty - Dr. Takátsy Anikó
• 11. Acids and bases, acid-base theories, acid-base reactions - Dr. Takátsy Anikó
• 12. Ion product constant of water, pH, pOH, hydrolysis of salts, pH-dependence of protonation - Dr. Takátsy Anikó
• 13. Buffer solutions - Dr. Takátsy Anikó
• 14. Buffer systems in living organisms - Dr. Berente Zoltán
• 15. Structure and formation of metal complexes. - Dr. Takátsy Anikó
• 16. Metal complexes in living organisms and in medical diagnosis - Dr. Berente Zoltán
• 17. Thermochemistry - Dr. Takátsy Anikó
• 18. Thermodynamics and the direction of chemical reactions - Dr. Nagy Veronika
• 19. Thermodynamics applied to living systems - Dr. Nagy Veronika
• 20. Reactionkinetics - Dr. Nagy Veronika
• 21. Steady-stateness, a characteristic of living systems - Dr. Nagy Veronika
• 22. Kinetic characteristics of cascade- and cyclic reactions - Dr. Nagy Veronika
• 23. Electrochemistry - Dr. Berente Zoltán
• 24. Electron transfer processes in living organisms - Dr. Berente Zoltán
• 25. Electrochemistry in the medical practice - Dr. Berente Zoltán
• 26. Basics of analytical chemistry for medical students - Dr. Takátsy Anikó
• 27. Basics of separation thechniques for medical students - Dr. Takátsy Anikó
• 28. Analitical instruments in medical diagnostics - Dr. Berente Zoltán
• 29. Reaction types in organic chemistry - Dr. Nagy Veronika
• 30. Saturated hydrocarbons: Alkanes. Paraffins in medicine - Dr. Nagy Veronika
• 31. Unsaturated hydrocarbons: Alkenes and alkynes - Dr. Nagy Veronika
• 32. Constitutional, conformational and geometric isomerism - Dr. Nagy Veronika
• 33. Optical isomerism. Relative and absolute configuration. - Dr. Nagy Veronika
• 34. Alcohols, enols, esters (including phosphate and sulphate esters) - Dr. Nagy Veronika
• 35. Phenols, quinones, ethers - Dr. Nagy Veronika
• 36. Aldehydes and their derivatives - Dr. Böddi Katalin
• 37. Carboxylic acids - Dr. Böddi Katalin
• 38. Carboxylic acid derivatives, acylating agents - Dr. Böddi Katalin
• 39. Organic sulfur compounds, thioesters - Dr. Nagy Veronika
• 40. Amines and their biologically significant derivatives - Dr. Nagy Veronika
• 41. Colloids - Dr. Berente Zoltán
• 42. Colloids found in living systems - Dr. Berente Zoltán

Practices

• 1. Laboratory regulations. Accident and fire protection
• 2. Laboratory regulations. Accident and fire protection
• 3. Introductory discussion
• 4. Introductory discussion
• 5. Experiments with compounds of halogens, oxygen-group and nitrogen group elements
• 6. Experiments with compounds of halogens, oxygen-group and nitrogen group elements
• 7. Experiments with compounds of carbon-group, aluminium and s-block elements
• 8. Experiments with compounds of carbon-group, aluminium and s-block elements
• 9. Discussion
• 10. Discussion
• 11. Titration of Betacid solution
• 12. Titration of Betacid solution
• 13. Potentiometry. Buffer solutions.
• 14. Potentiometry. Buffer solutions.
• 15. Reactions of coordinative (complex) compounds.
• 16. Reactions of coordinative (complex) compounds.
• 17. Experiments on colloidal systems, chemical equilibria, and catalysis
• 18. Experiments on colloidal systems, chemical equilibria, and catalysis
• 19. Experiments in electrochemistry
• 20. Experiments in electrochemistry
• 21. Organic chemistry I. Reactions of functional groups I
• 22. Organic chemistry I. Reactions of functional groups I
• 23. Organic chemistry I. Reactions of functional groups II
• 24. Organic chemistry I. Reactions of functional groups II
• 25. Organic chemistry I. Reactions of functional groups III
• 26. Organic chemistry I. Reactions of functional groups III
• 27. Closing remarks, repetition
• 28. Closing remarks, repetition

Seminars

• 1. Basic concepts, stoichiometric calculations
• 2. Stoichiometric calculations
• 3. Geometry and polarity of molecules. Intermolecular interactions
• 4. Concentration of solutions
• 5. Structure of simple organic molecules
• 6. Naming organic molecules. Isomerism
• 7. Structure and properties of various types of organic compounds
• 8. Stereochemistry I. Chirality, enantiomers
• 9. Stereochemistry II: Diastereomers
• 10. Reactions in organic chemistry I: Types of reactions
• 11. Reactions in organic chemistry II:Alkenes and aromatic compounds
• 12. Reactions in organic chemistry III:Alcohols
• 13. Reactions in organic chemistry IV:Aldehydes and ketones
• 14. Reactions in organic chemistry V:Carboxylic acids

Reading material

Obligatory literature

P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, latest edition, Univ. Med. School of Debrecen

Literature developed by the Department

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Notes

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Recommended literature

Veronika Nagy (ed.): Laboratory Experiments in Medical Chemistry, Internet edition, Univ. Med. School of Pécs, 2011
Hein-Pattison-Arena-Best: Introduction to Chemistry General, Organic, and Biochemistry, latest edition
P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, latest edition, Univ. Med. School of Debrecen

Conditions for acceptance of the semester

Maximum of 15 % absence allowed

Mid-term exams

During weeks 3-14 of the semester there are short tests at the beginning of each practice. Additional requirement for acceptance is writing 10 out of these 12 tests. It is obligatory to write lab-notes. Result of the short test is acknowledged only if the lab-note of the practice is accepted by the lab instructor.

Making up for missed classes

2 absences are allowed from the 14 occasions of lab and seminar practices.
The semester is not accepted if the student has more than 2 absences. If the student is late more than 5 minutes he/she can not write lab test. If the student is late 5-10 minutes, he/she may perform the lab experiments and this occasion will not be considered as an absence. Less than 5 minutes late is accepted. More than 10 minutes late is absence.
The lab and seminar classes cannot be made up.

Exam topics/questions

The exam is based on the topic of the lectures and labs. The lectures are identical with the General Medicine program.
http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Examiners

• Dr. Bognár Zita
• Dr. Bóna Ágnes
• Dr. Debreceni Balázs
• Dr. Jakus Péter Balázs

Instructor / tutor of practices and seminars

• Dr. Jakus Péter Balázs