Department of Biochemistry and Medical Chemistry · Subjects · Introduction to Biochemistry for Dentistry Students

Data

Official data in SubjectManager for the following academic year: 2022-2023

Course director

Dr. Balázs DEBRECENI

associate professor,
Department of Biochemistry and Medical Chemistry
balazs.debreceni@aok.pte.hu

Number of hours/semester

lectures: 28 hours

practices: 14 hours

seminars: 0 hours

total of: 42 hours

Subject data

Code of subject: OSA-BEF-T
3 kredit
Dentistry
Basic modul
spring

Prerequisites:

Exam course:

yes

Course headcount limitations

min. 1 – max. 96

Topic

Introduction to Biochemistry includes the topics of organic and bio-organic chemistry along with basic biochemistry which are necessary for dentistry students. It deals with the structure, chemistry, and cellular metabolism of essential biomolecules like proteins, carbohydrates and lipids. The purpose of practices is to consider the chemistry of bio-compounds. Curriculum of Introduction to Biochemistry contains the basic knowledge that is necessary to understand cell biology, physiology, pharmacology and biochemistry.

Lectures

1. Introduction - Dr. Bognár Zita
2. Carbonic acid derivatives, Heterocycles I. - Dr. Nagy Veronika
3. Heterocycles II. - Dr. Nagy Veronika
4. Alkaloids - Dr. Nagy Veronika
5. Simple and complex lipids - Dr. Nagy Veronika
6. Prostaglandins, terpenoids - Dr. Berente Zoltán
7. Steroids - Dr. Berente Zoltán
8. Structure of monosaccharides - Dr. Berente Zoltán
9. Reactions of monosaccharides - Dr. Nagy Veronika
10. Di-, oligo- and polysaccharides are medically important - Dr. Nagy Veronika
11. Amino acids, peptides - Dr. Nagy Veronika
12. Structure of proteins - Dr. Nagy Veronika
13. Hemoglobin, oxygen transport - Dr. Nagy Veronika
14. Myosin, Ig, scaffold - Dr. Nagy Veronika
15. Basics of enzyme kinetics - Dr. Jakus Péter Balázs
16. Regulation and inhibition of enzyme activity, isoenzymes - Dr. Jakus Péter Balázs
17. Biological membranes and transport processes I. - Dr. Jakus Péter Balázs
18. Biological membranes and transport processes II. - Dr. Takátsy Anikó
19. Nucleosides, nucleotides - Dr. Takátsy Anikó
20. Nucleic acids - Dr. Veres Balázs
21. Nucleotide coenzymes, bioenergetics - Dr. Veres Balázs
22. DNA I. Replication - Dr. Debreceni Balázs
23. DNA II. Corrective mechanisms - Dr. Debreceni Balázs
24. RNA I. Transcription - Dr. Veres Balázs
25. RNA II. Post-transcriptional changes - Dr. Veres Balázs
26. Proteins I. Translation - Dr. Tapodi Antal
27. Proteins II. Translation - Dr. Tapodi Antal
28. Proteins III. Regulation - Dr. Debreceni Balázs

Practices

1. Stereochemistry, molecule model exercises, -practice
2. Stereochemistry, molecule model exercises, -practice
3. Organic Chemistry I. - practice
4. Organic Chemistry I. - practice
5. Organic Chemistry II. - practice
6. Organic Chemistry II. - practice
7. Enzymes, metabolism I. - practice
8. Enzymes, metabolism I. - practice
9. Coenzymes - practice
10. Coenzymes - practice
11. Basics of molecular biology I.
12. Basics of molecular biology I.
13. Basics of molecular biology II.
14. Consultation

Seminars

Reading material

Obligatory literature

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Literature developed by the Department

Notes

Nagy V., Agócs A. :Introduction to biochemistry lab manual 2017/18http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Recommended literature

Nelson, Cox: Lehninger Principles of Biochemistry, 5th ed., W.H. Freeman, 2008
http://bcs.whfreeman.com/lehninger5e

Berg, Tymoczko, Stryer: Biochemistry, 7th ed.
http://bcs.whfreeman.com/berg7e

Conditions for acceptance of the semester

Maximum of 15 % absence allowed

Mid-term exams

There are lab practices at every EVEN NUMBERED EDUCATIONAL weeks (2-4-6-8-10-12-14). There are short tests from week 4 till 14. The lab is beginning with a short test (time is 6 minutes; 6 occasions; max. 6 exampoints). Requirement for acceptance is writing 5 test out of 6 possibility.
There is no possibilities to write a short test if delaying is over 5 minutes. No more than 10 minutes delay is accepted, over of it, it is an absence. No more than 1 absence is allowed from the 7 lab occasions (15%).
It is obligatory to write lab-notes. Result of the short test is acknowledged only if the lab-notes of the practice is accepted by the lab instructor. The exam is based on the topic of the lectures and labs. The lectures are identical with the General Medicine program. The exam conditions are on the website of the department. (http://aok.pte.hu/en/egyseg/oktatasianyagok/20)

Making up for missed classes

There is no possibility to make up of the lab practices.

Exam topics/questions