Main page
Education

Biochemistry for Dentistry Students

Data

Official data in SubjectManager for the following academic year: 2022-2023

Course director

Number of hours/semester

lectures: 42 hours

practices: 0 hours

seminars: 14 hours

total of: 56 hours

Subject data

  • Code of subject: OSA-BKZ-T
  • 4 kredit
  • Dentistry
  • Basic modul
  • autumn
Prerequisites:

OSA-OKF-T completed , OSA-BEF-T completed

Exam course:

yes

Course headcount limitations

min. 1 – max. 200

Topic

The subject gives an overview of the molecular processes occurring in living organisms from two major aspects. On the one hand, following the subject -Introduction to Biochemistry, it describes the metabolism of the four major types of biomolecules (carbohydrates, lipids, amino ac ids/proteins and nucleotides /nucleic acids) along with the indirect enzymatic regulation of
these processes. On the other hand, built on the subject -Molecular Cell Biology, accounts for the molecular processes responsible for the transmission of information within the living organisms from molecular biological (DNA-RNA-protein-metabolite) as well as hormonal point of view. The subject lies down the foundations of the subjects Pharmacology and Clinical Chemistry.

Lectures

  • 1. Introduction - Dr. Bognár Zita
  • 2. Overview of biochemical processes - Dr. Berente Zoltán
  • 3. Glycolysis reactions - Dr. Berente Zoltán
  • 4. Regulation of glycolysis - Dr. Berente Zoltán
  • 5. Metabolic pathways involved in glycolysis - Dr. Berente Zoltán
  • 6. The pentose phosphate pathway - Dr. Berente Zoltán
  • 7. Reactions of the PDC and citrate cycle - Dr. Bognár Zita
  • 8. Regulation of the citrate cycle - Dr. Bognár Zita
  • 9. Fatty acid oxidation - Dr. Bognár Zita
  • 10. Ketone bodies - Dr. Bognár Zita
  • 11. Respiratory chain and inhibition - Dr. Bognár Zita
  • 12. ATP synthesis - Dr. Bognár Zita
  • 13. Mitochondrial transport processes, pendulums - Dr. Radnai Balázs
  • 14. Gluconeogenesis in animal cells - Dr. Takátsy Anikó
  • 15. Synthesis and degradation of glycogen - Dr. Bognár Zita
  • 16. Regulation of glycogen synthesis and degradation - Dr. Bognár Zita
  • 17. Regulation and disorders of carbohydrate metabolism - Dr. Takátsy Anikó
  • 18. Biosynthesis of fatty acids (chain extension, desaturation) - Dr. Takátsy Anikó
  • 19. Biosynthesis of complex lipids - Dr. Bognár Zita
  • 20. Cholesterol, lipoproteins - Dr. Bognár Zita
  • 21. Regulation and disorders of lipid metabolism - Dr. Bognár Zita
  • 22. Amino acid metabolism; the fate of the amino group - Dr. Bognár Zita
  • 23. Urea cycle - Dr. Radnai Balázs
  • 24. Amino acid metabolism; the fate of the carbon skeleton - Dr. Radnai Balázs
  • 25. Biosynthesis of non-essential amino acids - Dr. Radnai Balázs
  • 26. Enzymopathies in amino acid metabolism - Dr. Radnai Balázs
  • 27. Biosynthesis of biologically active compounds from amino acids - Dr. Radnai Balázs
  • 28. Biosynthesis of purine and pyrimidine backbone nucleotides - Dr. Debreceni Balázs
  • 29. Degradation of purine and pyrimidine backbone nucleotides - Dr. Debreceni Balázs
  • 30. Protein-DNA interaction - Dr. Debreceni Balázs
  • 31. Regulation of gene expression - Dr. Debreceni Balázs
  • 32. Small RNAs - Dr. Debreceni Balázs
  • 33. Retroviruses - Dr. Debreceni Balázs
  • 34. Protein folding, PTM - Dr. Bognár Zita
  • 35. Targeting and degradation of proteins - Dr. Bognár Zita
  • 36. Hormones 1 - Dr. Bognár Zita
  • 37. Hormones 2 - Dr. Radnai Balázs
  • 38. Signal transmission I. - Dr. Radnai Balázs
  • 39. Signal transmission II. - Dr. Radnai Balázs
  • 40. Signal transmission III. - Dr. Tapodi Antal
  • 41. Water soluble vitamins - Dr. Tapodi Antal
  • 42. Fat-soluble vitamins - Dr. Tapodi Antal

Practices

Seminars

  • 1. Carbohydrate metabolism
  • 2. Carbohydrate metabolism
  • 3. Lipids - metabolism
  • 4. Lipids - metabolism
  • 5. Respiratory chain
  • 6. ATP calculation
  • 7. Amino acid metabolism
  • 8. Amino acid metabolism
  • 9. Purine and pyrimidine nucleotides
  • 10. Purine and pyrimidine nucleotides
  • 11. Student demonstrations
  • 12. Student demonstrations
  • 13. Consultation
  • 14. consultation

Reading material

Obligatory literature

Nelson, Cox: Lehninger Principles of Biochemistry, 6th edition, W.H. Freeman, 2013

Literature developed by the Department

www.aok.pte.hu

Notes

www.aok.pte.hu

Recommended literature

Berg, Tymoczko, Stryer: Biochemistry, 7th edition, W.H. Freeman, 2012.
Devlin: Textbook of Biochemistry with Clinical Correlations 7th edition, Wiley, 2010.

Conditions for acceptance of the semester

Maximum of 15 % absence allowed

Mid-term exams

It is obligatory to visit the lectures.

Making up for missed classes

Non

Exam topics/questions

The exam based on the lectures and labs of the previous semesters and the lectures of the actual semester.
After entering into the website of the UNI: http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Examiners

  • Dr. Bognár Zita
  • Dr. Debreceni Balázs

Instructor / tutor of practices and seminars

  • Dr. Bognár Zita
  • Dr. Debreceni Balázs
Rólunk