From the Chemistry Exam to the Final Exam in Biochemistry

Data

Official data in SubjectManager for the following academic year: 2022-2023

Topic

The goal of the current subject is preparing dentistry and medical students for the final exam (in Chemistry and Biochemistry). The major goal of the subject is to offer dentistry students - mainly who began their studies in 2016** - an integrative view of necessary knowledge in general, inorganic and organic chemistry, and biochemistry. The course highlights the relationships between topics covered by subjects 'Chemistry for Dentistry Students', 'Introduction to Biochemistry for Dentistry Students; and Biochemistry for Dentistry Students;. The course gives opportunity for both dentistry and medical students to raise questions and practice problem solving. The program also covers integrative regulation and relationships of metabolism.

Lectures

• 1. From Le'Chatelier to homeostasis. Osmolarity, pH in biochemistry. - Dr. Jakus Péter Balázs
• 2. From electron configuration to acidic strength; Buffer systems; From galvanic to mitochondria. Chemical properties of biomolecules. - Dr. Jakus Péter Balázs
• 3. From order to disorder. Why can life exist in the universe? Illustrative thermodynamics. - Dr. Jakus Péter Balázs
• 4. From reaction rate to enzyme activity. From enzyme inhibition to medication therapy. - Dr. Jakus Péter Balázs
• 5. Bioactive compounds. Relationship between structure and effect. - Dr. Jakus Péter Balázs
• 6. Organic Chemistry, reactions: From the test tube to the cell to the dentures. - Dr. Jakus Péter Balázs
• 7. From glyceraldehyde to carbohydrate degradation. - Dr. Jakus Péter Balázs
• 8. Store. Glycogen metabolism, glycogen metabolism regulation. Lipid storage, protein synthesis. - Dr. Jakus Péter Balázs
• 9. Glucose in the cytoplasm maze. Aspects of regulating carbohydrate metabolism. - Dr. Jakus Péter Balázs
• 10. Control of the citrate circle. - Dr. Jakus Péter Balázs
• 11. Lipid degradation B oxidation. Misconceptions about muscle fever. - Dr. Jakus Péter Balázs
• 12. From carbohydrates to fatty acids to obesity and arteriosclerosis. - Dr. Jakus Péter Balázs
• 13. Carbohydrates: From glyceraldehyde to carbohydrate degradation. Aspects of regulating carbohydrate metabolism. - Dr. Jakus Péter Balázs
• 14. Aspects of fat metabolism regulation. - Dr. Jakus Péter Balázs
• 15. Respiratory chain and associated reactions. Mitochondrial transport processes and ATP synthesis. - Dr. Jakus Péter Balázs
• 16. Biochemical Mathematics: How Many ATPs Are Created When Degrading Some Molecules? - Dr. Jakus Péter Balázs
• 17. Proteins: From glycine through protein function to urea. Importance of nucleic acid metabolism. - Dr. Jakus Péter Balázs
• 18. Importance of nucleic acid metabolism. Metabolic Diseases. - Dr. Jakus Péter Balázs
• 19. Towards future biochemistry: new RNA and DNA mechanisms, their regulation. - Dr. Jakus Péter Balázs
• 20. PCR, Cloning, CRISPR. - Dr. Jakus Péter Balázs
• 21. Signaling pathways. - Dr. Jakus Péter Balázs
• 22. Through hormones to gene expression. - Dr. Jakus Péter Balázs
• 23. Sample Test. - Dr. Jakus Péter Balázs
• 24. Disscussion of the sample test. - Dr. Jakus Péter Balázs

Practices

Seminars

Reading material

Obligatory literature

Nelson, Cox: Lehninger Principles of Biochemistry, 6th edition, W.H. Freeman, 2013

Literature developed by the Department

Notes

Nagy V.: Experiments is Med. Chem. lab manual, 2017
Nagy V.: Introduction to Biochemistry. lab manual, 2017

Recommended literature

Hein, Pattison: Introduction to General, Organic and Biochemistry. Wiley, 2015
Berg, Tymoczko, Stryer: Biochemistry, 7th edition, W.H. Freeman, 2012.
Devlin: Textbook of Biochemistry with Clinical Correlations 7th edition, Wiley, 2010.

Conditions for acceptance of the semester

Maximum of 25 % absence allowed

Mid-term exams

Midterm test at the 10th week.

Making up for missed classes

None

Exam topics/questions

http://aok.pte.hu/en/egyseg/index/20

Examiners

Instructor / tutor of practices and seminars