Data
Official data in SubjectManager for the following academic year: 2020-2021
Course director
-
Dr. Beáta LEMLI
assistant professor,
Department of Organic and Pharmacological Chemistry -
Number of hours/semester
lectures: 24 hours
practices: 0 hours
seminars: 0 hours
total of: 24 hours
Subject data
- Code of subject: OXE-SNA-r-T
- 2 kredit
- Pharmacy
- Elective modul
- both semesters
OHA-ALK-T completed
Course headcount limitations
min. 5 – max. 20
Topic
Carbon is an indispensable element of life, thanks to the ability to form different chemical bonds with most elements of the periodic table, enabling the creation of different and complex life forms. The discovery of the organic carbon compounds has been started in the 19th century, and now they are the part of our lives. Nowadays the previously discovered allotropes of carbon – fullerenes, carbon nanotubes, graphenes, graphene nanoribbons – are in the focus, however, their real wide application still seems to be a big challenge and needs further investigations. During this curse, students will be introduced to the promising pharmaceutical chemistry, medical and biological applications of these materials and to the latest results of related research.
Lectures
- 1. Introduction of the course requirements. Fullerenes, carbon nanostructure, graphene: their discovery, historical review - Dr. Lemli Beáta
- 2. Preparation, synthesis, cleaning, general properties - Dr. Lemli Beáta
- 3. Covalent and non-covalent functionalization of carbon nanomaterials - Dr. Lemli Beáta
- 4. Covalent and non-covalent functionalization of carbon nanomaterials - Dr. Lemli Beáta
- 5. Cellular uptake mechanism of carbon nanotubes - Dr. Lemli Beáta
- 6. Cellular uptake mechanism of carbon nanotubes - Dr. Lemli Beáta
- 7. Carbon nanotube biodistribution - Dr. Lemli Beáta
- 8. Carbon nanotube biodistribution - Dr. Lemli Beáta
- 9. Application of carbon nanocapsules in drug delivery - Dr. Lemli Beáta
- 10. Application of carbon nanocapsules in drug delivery - Dr. Lemli Beáta
- 11. Carbon nanotubes applied for in vitro, in vivo and in silico drug delivery - Dr. Lemli Beáta
- 12. Carbon nanotubes applied for in vitro, in vivo and in silico drug delivery - Dr. Lemli Beáta
- 13. Carbon nanostructures and DNA - Dr. Lemli Beáta
- 14. Carbon nanostructures and DNA - Dr. Lemli Beáta
- 15. Novel strategies for cancer diagnosis and treatment - Dr. Lemli Beáta
- 16. Novel strategies for cancer diagnosis and treatment - Dr. Lemli Beáta
- 17. The toxicity of carbon nanomaterials - Dr. Lemli Beáta
- 18. The toxicity of carbon nanomaterials - Dr. Lemli Beáta
- 19. Outlook: about the nanomedicines and drug delivery nanosystems - Dr. Lemli Beáta
- 20. Student’s lecture. - Dr. Lemli Beáta
- 21. Written test. - Dr. Lemli Beáta
- 22. Written test. - Dr. Lemli Beáta
- 23. Summary and conclusions - Dr. Lemli Beáta
- 24. Summary and conclusions - Dr. Lemli Beáta
Practices
Seminars
Reading material
Obligatory literature
Physical Biochemistry: Applications to Biochemistry and Molecular Biology (Life Sciences/Biochemistry) by David M. Freifelder, 2nd Edition, ISBN-13: 978-0716714446, ISBN-10: 0716714442
Literature developed by the Department
The slides of the lectures are electronically available.
Notes
Recommended literature
Physical Biochemistry: Applications to Biochemistry and Molecular Biology (Life Sciences/Biochemistry) by David M. Freifelder, 2nd Edition, ISBN-13: 978-0716714446, ISBN-10: 0716714442
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
One written exam during the semester, the acceptance level is 60%. One oral presentation by students.
Making up for missed classes
There is no possibility to make up for a missed lecture and practice
Exam topics/questions
The topics of the written test are similar to the topics of the lectures.