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SÉTÁLÓ, György

SÉTÁLÓ, György

M.D., Ph.D.

Telefon: +36 72 536001/31566

Supervisor of the following TDK topics

Supervisor: SÉTÁLÓ, György

The signaling of MAP-Kinases is studied in wild type and mutant rat pheochromocytoma (PC12) cell cultures. These enzymes are known mediators of neuronal differentiation and various stress inducers. Currently we are studying the effects of agents from the family of proteasome inhibitors (like MG-132 and epoxomicin) that can elicit neuronal differentiation in this cell type. Other members of the group are studying signaling mechanisms initiated by the peptide urocortin 2 in PC12 cells. From these observations the ability of this peptide ligand to modulate the action of nerve growth factor (NGF) appear to be especially interesting. The members of the research team: Alexandra Harci, OktáviaTarjányi  MD, Mónika Vecsernyés. We work in cooperation with Dr. Tamás Atlasz at Faculty of Sciences, UP