All colleagues of the unit

ZSIDÓ, Balázs Zoltán

ZSIDÓ, Balázs Zoltán

Telefon: 31649

Supervisor of the following TDK topics

Supervisor: HETÉNYI, Csaba

Co-supervisor: Dr. ZSIDÓ, Balázs Zoltán

Epigenetics plays an important role in the pathomechanisms of various diseases. Modifications of histone proteins of the nucleosome, the “histone code” is fundamental in understanding of diseases with epigenetic background. In this project, we will study the effect of the modifications on structure and interactions of histones focusing on their role in disease pathomechanisms. Structural bioinformatics tools will be applied in our investigations.

Supervisor: HETÉNYI, Csaba

Co-supervisor: Dr. ZSIDÓ, Balázs Zoltán

Attacking the assembly of HIV capsid is promising strategy of fighting AIDS. Proteins of the viral capsid are good targets of drug design due to their low mutation rates. In the project, available assembly inhibitors will be collected and their mechanisms will be investigated by computational techniques. Based on the collected information and the uncovered mechanisms, new inhibitors will be also designed.

Supervisor: HETÉNYI, Csaba

Co-supervisor: Dr. ZSIDÓ, Balázs Zoltán

GFR is an essential clinical parameter describing kidney function. The present topic involves a comparative literature survey of the methods of determination of GFR as creatinine clearance. In case we can find available literature and electronic healthcare records, we will apply statistical approaches to evaluate the significance of the state of art methods and will propose probable changes. Likewise, depending on the availability of data we will investigate the connection between physiological parameters (such as blood pressure) and GFR.

Supervisor: HETÉNYI, Csaba

Co-supervisor: Dr. ZSIDÓ, Balázs Zoltán

Current drug repositioning possibilities are investigated via generation and evaluation of target-ligand complex structures. During the research work, up-to-date pharmacoinformatic methods are applied.