Data
Official data in SubjectManager for the following academic year: 2021-2022
Course director
-
Dr. Gábor POZSGAI
associate professor,
Department of Pharmacology and Pharmacotherapy -
Number of hours/semester
lectures: 42 hours
practices: 0 hours
seminars: 0 hours
total of: 42 hours
Subject data
- Code of subject: OSP-FF1-T
- 3 kredit
- Dentistry
- Pre-clinical modul
- spring
OSP-KT2-T parallel , OSP-PO2-T parallel
Exam course:yes
Course headcount limitations
min. 2 – max. 30
Topic
The general aim of the subject is to provide the dentistry students with all the basic information in pharmacology necessary to understand the actions of drugs and the clinical pharmacotherapy. Pharmacology can be defined as the study of the manner in which the function of living systems is affected by chemical agents. Therefore, the students should be familiar with the basic knowledge of the physiological, pathophysiological and biochemical background of the pharmacological and therapeutic approaches. On the other hand, drug therapy is closely related to the clinical aspects of diseases.
The following topics will be dealt with. Definitions, prescription writing, drug development, drug formulations. General aspects of mechanisms of drug actions: characterization of drug-receptor interactions, mechanisms of drug antagonism, signal transduction mechanisms of drug receptors. General and quantitative aspects of pharmacokinetics: absorption, distribution and elimination of drugs. Pharmacology of the autonomic nervous system. Local anaesthetics.
Cardiovascular pharmacology: drugs used to treat congestive heart failure, antianginal, antiarrhythmic, antihypertensive drugs, diuretics, calcium channel blockers, drugs acting on the renin-angiotensin-aldosterone system. Drugs affecting haemostasis, haematopoesis and hyperlipoproteinaemias. Pharmacology of histamine, serotonin.
Lectures
- 1. Introduction to pharmacology - Dr. Hunyady Ágnes
- 2. Drug development - Dr. Bölcskei Kata
- 3. Basic mechanisms of drug effects. Characteristics of the agonist-receptor interaction I - Dr. Bölcskei Kata
- 4. Characteristics of the agonist-receptor interaction II - Dr. Pozsgai Gábor
- 5. Signal transduction. Tachyphylaxis and tolerance - Dr. Bölcskei Kata
- 6. Antagonism - Dr. Sánticsné Dr. Pintér Erika
- 7. Consultation on pharmacodynamics - Dr. Bölcskei Kata
- 8. Absorption and distribution - Dr. Csekő Kata
- 9. Biotransformation and excretion - Dr. Csekő Kata
- 10. Quantitative pharmacokinetics I. - Dr. Csekő Kata
- 11. Quantitative pharmacokinetics II. - Dr. Csekő Kata
- 12. Drug formulations I. - Dr. Tamasikné Dr. Helyes Zsuzsanna
- 13. Drug formulations II. - Dr. Tamasikné Dr. Helyes Zsuzsanna
- 14. Introduction to the pharmacology of the autonomic nervous - Dr. Pozsgai Gábor
- 15. Cholinergic agonists, cholinesterase inhibitors - Dr. Pozsgai Gábor
- 16. Muscarine receptor antagonists - Dr. Pozsgai Gábor
- 17. Peripheral muscle relaxants - Dr. Pozsgai Gábor
- 18. Drugs acting on synthesis, storage, release and elimination of catecholamines - Dr. Sánticsné Dr. Pintér Erika
- 19. Adrenergic receptor agonists - Dr. Sánticsné Dr. Pintér Erika
- 20. Adrenergic receptor antagonists - Dr. Sánticsné Dr. Pintér Erika
- 21. Local anaesthetics I - Dr. Sánticsné Dr. Pintér Erika
- 22. Local anaesthetics II - Dr. Sánticsné Dr. Pintér Erika
- 23. Calcium channel blockers - Dr. Tamasikné Dr. Helyes Zsuzsanna
- 24. Drugs acting on the renin-angiotensin-aldosterone system - Dr. Sánticsné Dr. Pintér Erika
- 25. Diuretics - Dr. Bölcskei Kata
- 26. Therapy of congestive heart failure - Dr. Tamasikné Dr. Helyes Zsuzsanna
- 27. Antianginal drugs - Dr. Pozsgai Gábor
- 28. Pharmacotherapy of hypertension - Dr. Horváth Ádám István
- 29. Anti-arrhythmic drugs - Dr. Horváth Ádám István
- 30. Histamine and histamine receptor antagonists - Dr. Horváth Ádám István
- 31. Serotonin, 5-HT receptor agonists and antagonists I - Dr. Bölcskei Kata
- 32. Serotonin, 5-HT receptor agonists and antagonists II - Dr. Bölcskei Kata
- 33. Eicosanoids I - Dr. Horváth Ádám István
- 34. Eicosanoids II - Dr. Horváth Ádám István
- 35. Drugs acting on smooth muscle - Dr. Csekő Kata
- 36. Pharmacotherapy of hyperlipoproteinemias - Dr. Bölcskei Kata
- 37. Drugs influencing haemostasis I - Dr. Tamasikné Dr. Helyes Zsuzsanna
- 38. Drugs influencing haemostasis II - Dr. Tamasikné Dr. Helyes Zsuzsanna
- 39. Drugs influencing haemostasis III - Dr. Tamasikné Dr. Helyes Zsuzsanna
- 40. Drugs influencing haematopoiesis - Dr. Tamasikné Dr. Helyes Zsuzsanna
- 41. Drugs acting on the respiratory system I - Dr. Csekő Kata
- 42. Drugs acting on the respiratory system II - Dr. Csekő Kata
Practices
Seminars
Reading material
Obligatory literature
Rang, Dale,B. Ritter, Moore: Pharmacology, 8th edition, Elsevier Churchill Livingstone, 2015.
G. Katzung (ed.): Basic and Clinical Pharmacology, 12th edition, Lange Medical Books/McGraw-Hill, 2012.
Literature developed by the Department
Intranet. Department of Pharmacology and Pharmacotherapy. Educational materials.
Neptun Meet Street
Notes
Recommended literature
Conditions for acceptance of the semester
For the semester to be accepted students are allowed to be absent from maximum 9 lectures.
Mid-term exams
There is no mid-term examination.
Making up for missed classes
Not possible
Exam topics/questions
1. Drug development
2. Basic mechanisms of drug effects
3. Characteristics of the agonist-receptor interaction
4. Signal transduction
5. Tachyphylaxis and tolerance. Antagonism
6. Absorption
7. Distribution
8. Biotransformation
9. Excretion
10. Quantitative pharmacokinetics
11. Cholinergic agonists. Cholinesterase inhibitors
12. Muscarine receptor antagonists
13. Peripheral muscle relaxants
14. Drugs acting on the synthesis, storage, release and elimination of catecholamines
15. Adrenergic receptor agonists
16. Adrenergic receptor antagonists
17. Histamine and histamine receptor antagonists
18. Serotonin, 5-HT receptor agonists and antagonists
19. Eicosanoids
20. Drugs influencing smooth muscles
21. Local anaesthetics
22. Calcium channel blockers
23. Drugs acting on the renin-angiotensin-aldosterone system
24. Diuretics
25. Pharmacotherapy of congestive heart failure
26. Antianginal drugs
27. Pharmacotherapy of hypertension
28. Anti-arrhythmic drugs
29. Pharmacotherapy of hyperlipoproteinemias
30. Drugs influencing haemostasis
31. Drugs influencing haematopoiesis
32. Drugs acting on the respiratory system: pharmacotherapy of bronchial asthma
33. Drugs acting on the respiratory system: Pharmacotherapy of allergic rhinitis, antitussive, expectorant and mucolytic drugs
Examiners
- Dr. Bölcskei Kata
- Dr. Csekő Kata
- Dr. Horváth Ádám István
- Dr. Pozsgai Gábor
- Dr. Sánticsné Dr. Pintér Erika
- Dr. Tamasikné Dr. Helyes Zsuzsanna