Drug Design 2

Data

Official data in SubjectManager for the following academic year: 2022-2023

Course director

  • Dr. Csaba HETÉNYI

    associate professor,
    Department of Pharmacology and Pharmacotherapy

Number of hours/semester

lectures: 12 hours

practices: 0 hours

seminars: 0 hours

total of: 12 hours

Subject data

  • Code of subject: OXEDR2-z-T
  • 1 kredit
  • Dentistry
  • Elective modul
  • spring
Prerequisites:

-

Course headcount limitations

min. 1 – max. 25

Available as Campus course for 5 fő számára. Campus-karok: ÁOK ETK GYTK TTK

Topic

The course is a continuation of its parent course Drug Design. Additional details of selected topics of the parent course and also new topics are provided. In Journal Club sessions, recent research articles will be featured with the students to deepen their knowledge in the areas discussed during the previous lectures. In this way, the students can discover further connections themselves and make sure of the usefulness of their newly obtained knowledge in drug design. The lectures will take place weekly or (if possible) contracted into 4 blocks.

Lectures

  • 1. Rational design: main concepts, phases, techniques and structure-activity relationships. - Dr. Hetényi Csaba
  • 2. Optimization of drug-target interactions (PD) and access to the target (PK). - Dr. Hetényi Csaba
  • 3. Antiviral design 1. - Dr. Zsidó Balázs Zoltán
  • 4. Antiviral design 2. - Dr. Zsidó Balázs Zoltán
  • 5. Antibacterial design. - Dr. Börzsei Rita Judit
  • 6. Targeting ion channels. - Dr. Zsidó Balázs Zoltán
  • 7. Targeting receptors 1. - Dr. Börzsei Rita Judit
  • 8. Targeting receptors 2. - Dr. Börzsei Rita Judit
  • 9. Targeting enzymes. - Dr. Börzsei Rita Judit
  • 10. The design of opioid analgesics. - Dr. Zsidó Balázs Zoltán
  • 11. Journal Club. - Dr. Hetényi Csaba
  • 12. Test writing. - Dr. Hetényi Csaba

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

The material of the course including pdfs of lectures and lists of questions will be made downloadable from the web site of the Department of Pharmacology and Pharmacotherapy or a link will be provided during the lectures / in an e-mail.

Notes

Recommended literature

Patrick GL: An Introduction to Medicinal Chemistry, Oxford University Press

Conditions for acceptance of the semester

Maximum of 25 % absence allowed

Mid-term exams

There is a final test announced at the end of the semester. The test will include multiple choice questions or short essays. A mark is offered according to the results of the written test or optionally by evaluation of the student's presentation prepared for the Journal Club. The student can improve the mark according to university regulations.

Making up for missed classes

Replacement is possible according to personal consultation.

Exam topics/questions

Lists of questions will be provided at the end of each lecture specifying the required knowledge.

Examiners

Instructor / tutor of practices and seminars