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GASZNER, Balázs

GASZNER, Balázs

MD, PhD, Dr. Habil.

associate professor

Department of Anatomy

Excellent practice instructor
2019, 2018, 2017, 2016, 2015

Supervisor of the following TDK topics

Supervisor: GASZNER, Balázs

Co-supervisor: Dr. PÉTERVÁRI, Erika

We know that several pathologies affecting the central nervous system, (depression, anorexia nervosa, anxiety disorders etc.), are more common in certain periods of life. The possible role of neuromodulators expressed in the central nervous in these conditions is known for a long time, and they are studied well. It his however less known whether the age-related changes in the neuropeptide expression would contribute to the characteristic cumulation of these conditions in some age groups. 

Supervisor: GASZNER, Balázs

Co-supervisor: Dr. KOVÁCS, László Ákos

Our adaptation ability to stressful events changes with age. By labeling activation markers the neuronal activation can be visualized in histological samples. The aim of the project is to map how the age-related alterations change the functions of various brain areas.  

Supervisor: GASZNER, Balázs

The neurpeptide urocortin1is a member of the corticotropin releasing factor peptide family. Its main expression site is the Edinger-Westphal nucleus. We have shown the activation of these cells in several stress models. The aim of the project is to test the effect of stress models to understand the function of the nucleus, and to map its the connections. 

Supervisor: GASZNER, Balázs

Co-supervisor: Dr. GASZNER, Tamás

Co-inciding genetic background, epigenetic effects and acquired chronic stress factors precipitate the symptoms of depression. The PACAP deficient mouse exerts depression like phenotype. Exposing them to maternal deprivation causing epigenetic changing, followed by chronic stress exposure in adulthood may provoke the occurrence of depression. To validate our model we perform behavioral tests, hormone measurements, determine the changes in brain neurotransmitter- and neuromodulator systems, and measure neuronal activation as well.