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AGÓCS, Attila

AGÓCS, Attila

PhD

associate professor , head of department

Department of Biochemistry and Medical Chemistry

Telefon: 31864

Supervisor of the following TDK topics

Supervisor: AGÓCS, Attila

Curcumin is a hot topic in contemporary research, as it shows very interesting biological effects regarding its tumor disease related activities, beside being a well known antioxidant and radical scavenger. Carotenoids, on the other hand, are a traditional research focus in the Research Group for Carotenoids with long tradition at our university. The covalent coupling of the two mentioned molecular moieties might lead to the enhancement in the antioxidant effects and possible further advantageous synergistic interactions widening the spectra of the individual biological properties. To be able to examine this proposed combination, the organic synthesis of the conjugates is underway and provides the prospective student an insight into the organic synthesis methods in theory and in practice.

Supervisor: AGÓCS, Attila

The antioxidant activity and bioavailability of hydrophilic carotenoids surpasses those of the natural parent carotenoids. As only a few such compounds are known in Nature our goal is the synthesis and pharmacological study of this kind of derivatives. Furthermore, dendrimers -already of nano size- built up from such carotenoid derivatives maybe of interest.