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KÉSMÁRKY, Gábor

KÉSMÁRKY, Gábor

Telefon: 32617, *0561

Head of division

Supervisor of the following TDK topics

Supervisor: KÉSMÁRKY, Gábor

Co-supervisor: Dr. KOLTAI, Katalin

Peripheral artery disease (PAD) is the progressive stenosis, occlusion or aneurysmatic dilatation of the aorta and its non-coronary vessels. Until now the medical care of PAD has been in the background compared to coronary artery disease (CAD) or cerebrovascular disease, despite that the number of limb amputation is 3-4 times higher compared to Western-Europe, meaning that most of these procedures can be prevented. Screening and diagnosis of PAD is important, because only 10% of PAD-patients have the well-known claudication intermittens. PAD also has a negative prognostic value: 55% of them die due to CAD. In our study we measure tissue oxygen tension and hemorheological parameters in PAD and also monitor their changes during treatment in order to find the most effective therapy.

Supervisor: KÉSMÁRKY, Gábor

Co-supervisor: Dr. BATTYÁNI, István

The ischemic heart disease (IHD) is the state of inadequate oxygen supply of the myocardium, in most cases caused by coronary artery disease. In the low-industrialised regions IHD is the 4th, while in the medium to high-industrialised countries it is the 1st most common cause of deaths, thus its early diagnosis is essential. Coronary CT is a new and well established method in the diagnosis of IHD. It is able to visualise the lumen and wall of the coronary vessels and the structure of the heart. In this topic we examine the changes of hemorheological parameters in different stages of coronary artery disease.

Supervisor: KÉSMÁRKY, Gábor

Co-supervisor: Dr. VÉKÁSI, Judit

Diabetic angiopathy is one of the late consequence of diabetes mellitus, which affects both small (microangiopathy) and large vessels (macroangiopathy). Diabetic macroangiopathy results in faster atherogenesis thus arteriolosclerosis and atherosclerosis appears more rapidly. Diabetic microangiopathy has three forms: neuropathy, nephropathy and retinopathy. Diabetic retinopathy is the 1st or 2nd most common cause of blindness in the developed world, its presence may be detected after 15 years of diabetes mellitus. Our aim is to screen patients suffering from diabetic retinopathy for silent – but instrumentally detectable – peripheral artery disease. The screening includes hemorheological and oxygen tissue tension measurements.

Supervisor: KÉSMÁRKY, Gábor

Peripheral vasospastic disorders are episodic, painful attacks of the acral parts caused by a local, diminished blood supply. The secondary form (Raynaud’s syndrome) can be associated with a number of different diseases, while the primary form (Raynaud’s disease) is idiopathic. During angiology consultation blood will be taken from patients suffering from peripheral vasospastic disorders. Detailed laboratory examinations will be performed, such as: cold agglutinin, cryoglobulin and hemorheological parameters. Tissue oxygen tension will also be measured.

Supervisor: KÉSMÁRKY, Gábor

Effect of compression elastic bandage on lower limb circulation in diseases of various etiology

Supervisor: KÉSMÁRKY, Gábor

Co-supervisor: Dr. KOLTAI, Katalin

A significant part of the population suffers from peripheral arterial diseases but the awareness of these diseases is much lower, the secondary prevention and even the symptomatic treatment are inappropriate frequently compared to the cardiovascular disorders. Therefore we are aiming to investigate those factors which can affect the blood and oxygen supplementation of the extremities performing cardiological, angiological, haemorheological and tissue oxygen tension examinations in order to be able to salvage the limbs and improve life quality. We examine the effects of the various pharmacological and non-pharmacological therapies on these variables and limb survival.

Supervisor: KÉSMÁRKY, Gábor

Co-supervisor: Dr. BIRÓ, Katalin

A significant part of the population suffers from peripheral arterial diseases but the awareness of these diseases is much lower, the secondary prevention and even the symptomatic treatment are inappropriate frequently compared to the cardiovascular disorders. Therefore we are aiming to investigate those factors which can affect the blood and oxygen supplementation of the extremities performing cardiological, angiological, haemorheological and tissue oxygen tension examinations in order to be able to salvage the limbs and improve life quality. We examine the effects of the various pharmacological and non-pharmacological therapies on these variables and limb survival.

Supervisor: KÉSMÁRKY, Gábor

Co-supervisor: Dr. CSISZÁR, Beáta

Blood flow properties and blood cell characteristics can be altered in several diseases: they can provoke symptoms in a part of diseases or they can be co-factors in other ones. The haemorheological parameters could be valuable in risk stratification and diagnostics. In our laboratory haemorheological investigations are performed at various patient populations: plasma and whole blood viscosity, red blood cell aggregation and deformability, platelet aggregation are measured and they are analysed in respect of clinical parameters. The clinical usefulness of a novel variable, haematocrit and blood viscosity ratio characterising the oxygen carrying capacity of blood is evaluated.

Supervisor: KÉSMÁRKY, Gábor

Co-supervisor: Dr. KOLTAI, Katalin

Non-invasive angiological tests in patients at high risk for peripheral artery disease