Supervisor: MEZŐSI, Emese
Co-supervisor: Dr. TÓTSIMON, Kinga
Our knowledge about the hemorheological changes in thyroid disorders is diffuse. In patients with hypothyroidism we experience increased bleeding risk, in hyperthyroidism we see the elevation of the incidence of thromboembolic events. The cause of death in hyperthyroidism is in 18% pulmonal embolism. An other common endocrine disorder which is accompanied by obviously increased risk for cardiovascular death is the exogenous and endogenous glucocorticoid overproduction. Our study wishes to investigate the non-genomic effect of thyroid hormones on platelet aggregation, and the in vitro effect of glucocorticoids on rheological parameters in healthy volunteers.