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Education

Biochemistry I

Data

Official data in SubjectManager for the following academic year: 2023-2024

Course director

Number of hours/semester

lectures: 14 hours

practices: 0 hours

seminars: 28 hours

total of: 42 hours

Subject data

  • Code of subject: OTV-BIC1-T
  • 3 kredit
  • Biotechnology BSc
  • Specialised Core Module modul
  • spring
Prerequisites:

OTN-GENC-T completed , OTV-SEBI-T completed

Exam course:

yes

Course headcount limitations

min. 1

Topic

In the Biochemistry I subject, the students will study the macromolecules, which build up the eukaryotic cells. They learn about the most important energy providing pathways (glycolysis, citric acid cycle, fatty acid degradation, photosynthesis), and the major biosynthetic pathways (glycogen, lipid, amino acid and nucleotide synthesis). In addition, we will deal with the basic biochemistry of prokaryotic and plant cells, as they are widely used in biotechnology.

Lectures

  • 1. Introduction. Metabolic pathways - Dr. Sipos Katalin
  • 2. Glycolysis - Dr. Sipos Katalin
  • 3. Gluconeogenesis. Cori cycle - Dr. Farkas Viktória
  • 4. Metabolism of glycogen - Dr. Farkas Viktória
  • 5. Pyruvate dehydrogenase complex - Dr. Farkas Viktória
  • 6. Pentose phosphate pathway - Pap Ramóna
  • 7. Degradation of fatty acids - Dr. Sipos Katalin
  • 8. Citric acid cycle - Dr. Sipos Katalin
  • 9. Terminal oxidation, ATP synthesis - Dr. Farkas Viktória
  • 10. Ketone bodies - Dr. Farkas Viktória
  • 11. Biosynthesis of fatty acids - Dr. Farkas Viktória
  • 12. Metabolism of cholesterol - Dr. Farkas Viktória
  • 13. Amino acids - Pap Ramóna
  • 14. Nucleic acids: building blocks, structure - Pap Ramóna

Practices

Seminars

  • 1. Basic regulatory processes of metabolism
  • 2. Thermodynamics, biochemical reactions
  • 3. Carbohydrates
  • 4. Carbohydrates
  • 5. Enzymology - the basics
  • 6. Enzyme kinetics
  • 7. Inhibition of enzymes
  • 8. Regulation of enzymes
  • 9. Enzymes in biotechnology
  • 10. Enzymes in biotechnology
  • 11. Importance of carbohydrates in biotechnology
  • 12. Metabolism of complex carbohydrates
  • 13. Lipids
  • 14. Importance of lipids in biotechnology.
  • 15. Anaplerotic processes.
  • 16. Metabolism of complex lipids.
  • 17. Clinical importance of terminal oxidation.
  • 18. Carbohydrates – summary.
  • 19. Energy production in plants.
  • 20. Carbohydrate metabolism in plants.
  • 21. Energy production in bacteria
  • 22. Energy production in bacteria
  • 23. Lipids, energy production – summary
  • 24. Lipids, energy production – summary
  • 25. Structure of proteins.
  • 26. Purification of proteins.
  • 27. Consultation
  • 28. Consultation

Reading material

Obligatory literature

Literature developed by the Department

The materials of the lectures and seminars will appear on Neptune.

Notes

Recommended literature

Ch. P. Woodbury: Biochemistry for the Pharmaceutical Sciences
Raymond S. Ochs: Biochemistry
Thomas M. Devlin: Textbook of Biochemistry with Clinical Correlations

Conditions for acceptance of the semester

Maximum of 25 % absence allowed

Mid-term exams

There is no written mid-term exam in the semester.

Making up for missed classes

According to personal agreement

Exam topics/questions

There are no given exam questions. The topics of the exam will be the materials of lectures and seminars.

Examiners

  • Dr. Farkas Viktória
  • Dr. Pandur Edina
  • Dr. Sipos Katalin

Instructor / tutor of practices and seminars

  • Dr. Farkas Viktória
  • Dr. Horváth Adrienn
  • Dr. Pandur Edina
  • Dr. Sipos Katalin
  • Jánosa Gergely
Rólunk