Supervisor: GOMBOS, Katalin

The purpose of the study is the quantitative and structural analysis of circulating exosomal miRNA fraction from body fluids using quantitative real-time PCR platform. Many genes are subject of miRNA regulation, thus the recognition of extracellular miRNA (circulating miRNA) in biological fluids has generated an interest for their potential use of markers for progressive human diseases. These molecules have emerging role as liquid biopsy-based markers. Principally our research focuses on serum and saliva miRNA expression analysis compared to tissue expressions in head and neck cancer.     

Supervisor: GOMBOS, Katalin

The purpose of the study is the quantitative and structural analysis of circulating exosomal miRNA fraction from body fluids using quantitative real-time PCR platform. Many genes are subject of miRNA regulation, thus the recognition of extracellular miRNA (circulating miRNA) in biological fluids has generated an interest for their potential use of markers for progressive human diseases. These molecules have emerging role as liquid biopsy-based markers. Principally our research focuses on serum and saliva miRNA expression analysis compared to tissue expressions in head and neck cancer.