Supervisor: GOMBOS, Katalin

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel human pathogene that causes coronavirus disease 2019 (COVID-19). To support infection control measures, there is an urgent need for accurate molecular diagnostics to identify COVID-19 positive individuals and uncover pathogenic risk factors related to the development of the symptomatic disease. The recent topic is focusing on highly sensitive and specific molecular  diagnostic techniques targeting the RNA-dependent RNA polymerase (RdRp)/helicase (Hel), spike (S), envelope (E) and nucleocapsid (N) genes of SARS-CoV-2 and predisposing genetic and epigenetic factors that prone individuals to severe disease progression.

Supervisor: GOMBOS, Katalin

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel human pathogene that causes coronavirus disease 2019 (COVID-19). To support infection control measures, there is an urgent need for accurate molecular diagnostics to identify COVID-19 positive individuals and uncover pathogenic risk factors related to the development of the symptomatic disease. The recent topic is focusing on highly sensitive and specific molecular  diagnostic techniques targeting the RNA-dependent RNA polymerase (RdRp)/helicase (Hel), spike (S), envelope (E) and nucleocapsid (N) genes of SARS-CoV-2 and predisposing genetic and epigenetic factors that prone individuals to severe disease progression.

Supervisor: GOMBOS, Katalin

The purpose of the study is the quantitative and structural analysis of circulating exosomal miRNA fraction from body fluids using quantitative real-time PCR platform. Many genes are subject of miRNA regulation, thus the recognition of extracellular miRNA (circulating miRNA) in biological fluids has generated an interest for their potential use of markers for progressive human diseases. These molecules have emerging role as liquid biopsy-based markers. Principally our research focuses on serum and saliva miRNA expression analysis compared to tissue expressions in head and neck cancer.     

Supervisor: GOMBOS, Katalin

The purpose of the study is the quantitative and structural analysis of circulating exosomal miRNA fraction from body fluids using quantitative real-time PCR platform. Many genes are subject of miRNA regulation, thus the recognition of extracellular miRNA (circulating miRNA) in biological fluids has generated an interest for their potential use of markers for progressive human diseases. These molecules have emerging role as liquid biopsy-based markers. Principally our research focuses on serum and saliva miRNA expression analysis compared to tissue expressions in head and neck cancer.