Pharmaceutical Chemistry 1 - Practice

Data

Official data in SubjectManager for the following academic year: 2024-2025

Topic

Introduction to the quality control of substances used in pharmaceutical compounding. Pharmacopoeal analysis of selected inorganic substances.

Lectures

Practices

• 1. Laboratory safety and accident protection. The pharmacopoeial nomenclature of substances. Identification and qualitative tests of the European Pharmacopoeia. Limit tests. Acidum hydrochloridum dilutum.
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  2. Laboratory safety and accident protection. The pharmacopoeial nomenclature of substances. Identification and qualitative tests of the European Pharmacopoeia. Limit tests. Acidum hydrochloridum dilutum.

  3. Laboratory safety and accident protection. The pharmacopoeial nomenclature of substances. Identification and qualitative tests of the European Pharmacopoeia. Limit tests. Acidum hydrochloridum dilutum.
• 4. Laboratory safety and accident protection. The pharmacopoeial nomenclature of substances. Identification and qualitative tests of the European Pharmacopoeia. Limit tests. Acidum hydrochloridum dilutum.
• 5. Calculation of results. Experimental errors. Natrii chloridum, Chloraminum.
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  6. Calculation of results. Experimental errors. Natrii chloridum, Chloraminum.

  7. Calculation of results. Experimental errors. Natrii chloridum, Chloraminum.
• 8. Calculation of results. Experimental errors. Natrii chloridum, Chloraminum.
• 9. Inorganic pharmacopoeial substances I. Halogens Natrii bromidum., Kalii bromidum, Ammonii bromidum, Kalii chloridum.
• 10. Inorganic pharmacopoeial substances I. Halogens Natrii bromidum., Kalii bromidum, Ammonii bromidum, Kalii chloridum.
• 11. Inorganic pharmacopoeial substances I. Halogens Natrii bromidum., Kalii bromidum, Ammonii bromidum, Kalii chloridum.
• 12. Inorganic pharmacopoeial substances I. Halogens Natrii bromidum., Kalii bromidum, Ammonii bromidum, Kalii chloridum.
• 13. Inorganic pharmacopoeial substances II. Oxygen group.. Aqua purificata, Hydrogenii peroxidum 30 per centum, Natrii hydroxidum.
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  14. Inorganic pharmacopoeial substances II. Oxygen group.. Aqua purificata, Hydrogenii peroxidum 30 per centum, Natrii hydroxidum.

  15. Inorganic pharmacopoeial substances II. Oxygen group.. Aqua purificata, Hydrogenii peroxidum 30 per centum, Natrii hydroxidum.
• 16. Inorganic pharmacopoeial substances II. Oxygen group.. Aqua purificata, Hydrogenii peroxidum 30 per centum, Natrii hydroxidum.
• 17. Inorganic pharmacopoeial substances III. Sulphur compounds. Natrii thiosulfas, Natrii metabisulfis, Natrii sulfas, Sulphur ad usum externum.
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  18. Inorganic pharmacopoeial substances III. Sulphur compounds. Natrii thiosulfas, Natrii metabisulfis, Natrii sulfas, Sulphur ad usum externum.

  19. Inorganic pharmacopoeial substances III. Sulphur compounds. Natrii thiosulfas, Natrii metabisulfis, Natrii sulfas, Sulphur ad usum externum.
• 20. Inorganic pharmacopoeial substances III. Sulphur compounds. Natrii thiosulfas, Natrii metabisulfis, Natrii sulfas, Sulphur ad usum externum.
• 21. Inorganic pharmacopoeial substances IV. Nitrogen compounds. Ammonii chloridum, Natrii nitris, Kalii nitras, Bismuthi subnitras.
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  22. Inorganic pharmacopoeial substances IV. Nitrogen compounds. Ammonii chloridum, Natrii nitris, Kalii nitras, Bismuthi subnitras.

  23. Inorganic pharmacopoeial substances IV. Nitrogen compounds. Ammonii chloridum, Natrii nitris, Kalii nitras, Bismuthi subnitras.
• 24. Inorganic pharmacopoeial substances IV. Nitrogen compounds. Ammonii chloridum, Natrii nitris, Kalii nitras, Bismuthi subnitras.
• 25. Inorganic pharmacopoeial substances V. Phosphorous compounds. Calcii hydrogenophosphas, Tricalcii phosphas, Natrii dihydrogenophosphas, Dinatrii phosphas
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  26. Inorganic pharmacopoeial substances V. Phosphorous compounds. Calcii hydrogenophosphas, Tricalcii phosphas, Natrii dihydrogenophosphas, Dinatrii phosphas

  27. Inorganic pharmacopoeial substances V. Phosphorous compounds. Calcii hydrogenophosphas, Tricalcii phosphas, Natrii dihydrogenophosphas, Dinatrii phosphas
• 28. Inorganic pharmacopoeial substances V. Phosphorous compounds. Calcii hydrogenophosphas, Tricalcii phosphas, Natrii dihydrogenophosphas, Dinatrii phosphas
• 29. Inorganic pharmacopoeial substances VI. Carbon compounds. Carbo activatus, Calcii carbonas, Natrii carbonas, Natrii hydrogencarbonas.
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  30. Inorganic pharmacopoeial substances VI. Carbon compounds. Carbo activatus, Calcii carbonas, Natrii carbonas, Natrii hydrogencarbonas.

  31. Inorganic pharmacopoeial substances VI. Carbon compounds. Carbo activatus, Calcii carbonas, Natrii carbonas, Natrii hydrogencarbonas.
• 32. Inorganic pharmacopoeial substances VI. Carbon compounds. Carbo activatus, Calcii carbonas, Natrii carbonas, Natrii hydrogencarbonas.
• 33. Inorganic pharmacopoeial substances VII. Pharmaceutical excipients (Seminars). Silicon compounds. Magnesii trisilicas, Silica, colloidal hydrated.
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  34. Inorganic pharmacopoeial substances VII. Pharmaceutical excipients (Seminars). Silicon compounds. Magnesii trisilicas, Silica, colloidal hydrated.

  35. Inorganic pharmacopoeial substances VII. Pharmaceutical excipients (Seminars). Silicon compounds. Magnesii trisilicas, Silica, colloidal hydrated.
• 36. Inorganic pharmacopoeial substances VII. Pharmaceutical excipients (Seminars). Silicon compounds. Magnesii trisilicas, Silica, colloidal hydrated.
• 37. Inorganic pharmacopoeial substances VIII. Alkaline earth metals. Earth metals. Magnesii sulfas, Magnesii subcarbonas, Magnesii oxydum, Acidum boricum, Borax.
• 38. Inorganic pharmacopoeial substances VIII. Alkaline earth metals. Earth metals. Magnesii sulfas, Magnesii subcarbonas, Magnesii oxydum, Acidum boricum, Borax.
• 39. Inorganic pharmacopoeial substances VIII. Alkaline earth metals. Earth metals. Magnesii sulfas, Magnesii subcarbonas, Magnesii oxydum, Acidum boricum, Borax.
• 40. Inorganic pharmacopoeial substances VIII. Alkaline earth metals. Earth metals. Magnesii sulfas, Magnesii subcarbonas, Magnesii oxydum, Acidum boricum, Borax.
• 41. Inorganic pharmacopoeial substances IX. Metals. Aluminii oxidum hydricum, Aluminii sulfas, Zinci oxydum, Zinci chloridum, Ferrosi sulfas, Kalii permanganas.
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  42. Inorganic pharmacopoeial substances IX. Metals. Aluminii oxidum hydricum, Aluminii sulfas, Zinci oxydum, Zinci chloridum, Ferrosi sulfas, Kalii permanganas.

  43. Inorganic pharmacopoeial substances IX. Metals. Aluminii oxidum hydricum, Aluminii sulfas, Zinci oxydum, Zinci chloridum, Ferrosi sulfas, Kalii permanganas.
• 44. Inorganic pharmacopoeial substances IX. Metals. Aluminii oxidum hydricum, Aluminii sulfas, Zinci oxydum, Zinci chloridum, Ferrosi sulfas, Kalii permanganas.
• 45. Physico-chemical parameters influencing the biological effect (solubility, pKa, logP). Determination of logP.
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  46. Physico-chemical parameters influencing the biological effect (solubility, pKa, logP). Determination of logP.

  47. Physico-chemical parameters influencing the biological effect (solubility, pKa, logP). Determination of logP.
• 48. Physico-chemical parameters influencing the biological effect (solubility, pKa, logP). Determination of logP.
• 49. Classification of functional groups and heterocycles (seminar). Assay for Kalii nitras.
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  50. Classification of functional groups and heterocycles (seminar). Assay for Kalii nitras.

  51. Classification of functional groups and heterocycles (seminar). Assay for Kalii nitras.
• 52. Classification of functional groups and heterocycles (seminar). Assay for Kalii nitras.
• 53. Basics of stereochemistry. Stereochemistry of morphine and derivatives.
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  54. Basics of stereochemistry. Stereochemistry of morphine and derivatives.

  55. Basics of stereochemistry. Stereochemistry of morphine and derivatives.
• 56. Basics of stereochemistry. Stereochemistry of morphine and derivatives.

Seminars

Reading material

Obligatory literature

Literature developed by the Department

Attila Almási, Zsuzsanna Rozmer, Pál Perjési: Pharmaceutical Chemistry I. Laboratory Experiments and Commentary, electronic educational material, PTE 2014.

Notes

Pharmaceutical Chemistry Practice I., Laboratory manual, University of Pécs, 2015.

Recommended literature

Conditions for acceptance of the semester

Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation in the practices is obligatory. Maximum three absences can be accepted. Students have to write at least four short tests on the practices. The average of the results must be at least 50%. Quantitative measurements should be carried out with the acceptance level of 70%! The practical work (results of the written tests and the experimental work) is evaluated by a practice grade.

Mid-term exams

The short practical test can be made up on the next practical.

Making up for missed classes

There is no opportunity to make up missed practices.

Exam topics/questions

Questions of the above short tests are from the topics of the practical and seminary.

Examiners

Instructor / tutor of practices and seminars

• Almási Attila
• Mészáros Petra