Pharmaceutical Chemistry 3 - Theory

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

lectures: 42 hours

practices: 0 hours

seminars: 0 hours

total of: 42 hours

Subject data

  • Code of subject: OPG-R3E-T
  • 3 kredit
  • Pharmacy
  • Pharmaceutical theoretical module and practical skills modul
  • autumn
Prerequisites:

OPG-R2E-T finished , OPG-R3G-T parallel

Course headcount limitations

min. 5 – max. 50

Topic

Introduction to molecular aspect, structure-activity relationship and pharmacopoeal qualification of selected group of active pharmaceutical ingredients. Basic principles and application of the analytical methods most frequently used in the pharmacopoeal qualifications.

Lectures

  • 1. Application of CD and ORD spectroscopy in pharmaceutical analysis. - Rozmer Zsuzsanna
  • 2.

    Application of UV-Vis spectroscopy in pharmaceutical analysis

    - Rozmer Zsuzsanna
  • 3.

    Application of UV-Vis spectroscopy in pharmaceutical analysis.

    - Rozmer Zsuzsanna
  • 4. Application of thermoanalytic methods in pharmaceutical analysis. - Kulcsár Győző Kornél
  • 5.

    Application of fluorimetry in pharmaceutical analysis.

    - Tyukodi Levente
  • 6.

    Application of fluorimetry in pharmaceutical analysis.

    - Tyukodi Levente
  • 7. Application of atomic absorption spectrometry and flame photometry in pharmaceutical analysis. - Kulcsár Győző Kornél
  • 8.

    Application of IR spectroscopy in pharmaceutical analysis.

    - Kulcsár Győző Kornél
  • 9.

    Application of IR spectroscopy in pharmaceutical analysis.

    - Kulcsár Győző Kornél
  • 10. Biological drugs I. - Fülöpné Kiss Edit
  • 11.

    Application of NMR spectroscopy in pharmaceutical analysis.

    - Kulcsár Győző Kornél
  • 12.

    Application of NMR spectroscopy in pharmaceutical analysis.

    - Kulcsár Győző Kornél
  • 13. Biological drugs II. - Fülöpné Kiss Edit
  • 14. Application of mass spectrometry in pharmaceutical analysis. - Kulcsár Győző Kornél
  • 15. Application of mass spectrometry in pharmaceutical analysis. - Kulcsár Győző Kornél
  • 16. Antiallergic antihistamines. Drugs for rheumatic gout I. - Rozmer Zsuzsanna
  • 17.

    Application of electroanalytical methods in pharmaceutical analysis.

    - Tyukodi Levente
  • 18.

    Application of electroanalytical methods in pharmaceutical analysis.

    - Tyukodi Levente
  • 19. Antiallegic antihistamines. Drugs for rheumatic gout II. - Rozmer Zsuzsanna
  • 20. Agents of cardiac failure. - Rozmer Zsuzsanna
  • 21. Agents of cardiac failure. - Rozmer Zsuzsanna
  • 22. Antianginal drugs. - Rozmer Zsuzsanna
  • 23. Agents of antiarythmic agents. - Almási Attila
  • 24. Agents of antiarythmic agents. - Almási Attila
  • 25. Antithrombotics, Thrombolytics, Coagulants I. - Rozmer Zsuzsanna
  • 26. Antihipertensive agents. - Almási Attila
  • 27. Antihipertensive agents. - Almási Attila
  • 28. Antithrombotics, Thrombolytics, Coagulants II. - Rozmer Zsuzsanna
  • 29. Antihiperlidemic agents. - Rozmer Zsuzsanna
  • 30. Antihiperlidemic agents. - Rozmer Zsuzsanna
  • 31. Drugs affecting thyroid functions. - Kovács-Rozmer Katalin
  • 32. Diuretics. - Almási Attila
  • 33. Diuretics. - Almási Attila
  • 34.

    Adrenocorticoids I.

    - Rozmer Zsuzsanna
  • 35. Drugs affecting calcium homeostatis. - Rozmer Zsuzsanna
  • 36. Drugs affecting calcium homeostatis. - Rozmer Zsuzsanna
  • 37.

    Adrenocorticoids II.

    - Rozmer Zsuzsanna
  • 38. Insulin and oral hypoglycemic drugs. - Almási Attila
  • 39. Insulin and oral hypoglycemic drugs. - Almási Attila
  • 40.

    Estrogens, Androgens, Progestins I.

    - Rozmer Zsuzsanna
  • 41.

    Estrogens, Androgens, Progestins II.

    - Rozmer Zsuzsanna
  • 42.

    Estrogens, Androgens, Progestins II.

    - Rozmer Zsuzsanna

Practices

Seminars

Reading material

Obligatory literature

D.A. Williams, T.L. Lemke (eds.): Foye's Principles of Medicinal Chemistry, 7th edition, Lippincott Williams & Wilkins, Philadelphia, 2013

Literature developed by the Department

Attila Almási, Zsuzsanna Rozmer, Pál Perjési: Pharmaceutical Chemistry 1. Laboratory Experiments and Commentary, electronic educational material, PTE 2014

Notes

Recommended literature

European Pharmacopoeia, EDQM Publication

Lecture notes.

Conditions for acceptance of the semester

Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation is both the lectures and the practices is obligatory. Maximum three absences can be accepted both from lectures and practices. Students have to write two midterm tests (week 7. and 12.) from the topics of the theory and the practice. One of the test result should be above 60%, the average of the tests should be above 50%. One re-take test is allowed at the 14th weak of the semester. Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester.

Mid-term exams

Students have to write two midterm tests (week 7. and 12.) from the topics of the theory and the practice. One of the test result should be above 60%, the average of the tests should be above 50%. One re-take test is allowed at the 14th weak of the semester. Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester.

Making up for missed classes

There is no opportunity to make up missed classes.

Exam topics/questions

Written exam covering the topics of the lectures and the laboratory practices. The result of the written exam must be above 60%. The final grade is based on results of the midterm tests and the written exam. Maximum contribution of the results of the midterm tests to the total score of the written exam is 20%.

Examiners

  • Kulcsár Győző Kornél
  • Mészáros Petra
  • Rozmer Zsuzsanna
  • Tyukodi Levente

Instructor / tutor of practices and seminars