Pharmaceutical Technology 1 - Theory

Data

Official data in SubjectManager for the following academic year: 2022-2023

Topic

Courses of pharmaceutical technology are taught in the 3rd and 4th years of school of pharmacy. Aim of courses of Pharmaceutical Technology is introducing basic technological processes, preformulation and formulation of pharmaceutical dosage forms taking into account physico-chemical, pharmaceutical and biopharmaceutical properties of active agents and pharmaceutical excipients.
Further studies include review of national and international pharmacopoeias.
Practices usually begin with seminars where basic introduction of the proper lesson takes place. After seminars students have to prepare medicines according to the laws of pharmaceutical formulation technology in proper dosage forms including calculation of single and daily maximal dose, preparation, labeling and pricing. Students also have to prepare galenic formulations according to the official formula. Practices of quality control of medicines are carried out as well.
Course Pharmaceutical Technology 1 includes practice with liquid dosage forms such as solution, syrup, elixir, oral drop, ear drop, nasal drop, parenteral solution and associated calculations with practices of quality control of mentioned dosage forms.

Lectures

• 1. Defination of medication and dosage form. History of preparation of medications. The subjects and tasks of pharmaceutical technology, basic terms. - Dr. Pál Szilárd
• 2. Defination of medication and dosage form. History of preparation of medications. The subjects and tasks of pharmaceutical technology, basic terms. - Dr. Pál Szilárd
• 3. Dispensing and compounding at a pharmacy (measurement, treatment of substances) - Dr. Pál Szilárd
• 4. Dispensing and compounding at a pharmacy (measurement, treatment of substances) - Dr. Pál Szilárd
• 5. Basics of technological operations, biopharmaceutical aspects - Dr. Pál Szilárd
• 6. Basics of technological operations, biopharmaceutical aspects - Dr. Pál Szilárd
• 7. Technological importance of substances - Dr. Pál Szilárd
• 8. Technological importance of substances - Dr. Pál Szilárd
• 9. Dissolution - Dr. Secenji Aleksandar
• 10. Written test - Dr. Pál Szilárd
• 11. Excipients used to increase of API's solubility - Dr. Pál Szilárd
• 12. Excipients used to increase of API's solubility - Dr. Pál Szilárd
• 13. Mixing and stirring - Ámanné Dr. Takácsi-Nagy Anna Erzsébet
• 14. Mixing and stirring - Ámanné Dr. Takácsi-Nagy Anna Erzsébet
• 15. Heat transferes - Dr. Secenji Aleksandar
• 16. Heat transferes - Dr. Secenji Aleksandar
• 17. Interaction and incompatibility of pharmaceutical preparations - Dr. Pál Szilárd
• 18. Interaction and incompatibility of pharmaceutical preparations - Dr. Pál Szilárd
• 19. Written test - Dr. Pál Szilárd
• 20. Written test - Dr. Pál Szilárd
• 21. Sterilization, depyrogenation, aseptic working, eye preparations - Dr. Pál Szilárd
• 22. Sterilization, depyrogenation, aseptic working, eye preparations - Dr. Pál Szilárd
• 23. Preparation and examination of injection (API, excipients, solvents, containers, examination) - Dr. Pál Szilárd
• 24. Preparation and examination of injection (API, excipients, solvents, containers, examination) - Dr. Pál Szilárd
• 25. Infusions and implants. The most important class of injectable and plantable preparations - Dr. Pál Szilárd
• 26. Infusions and implants. The most important class of injectable and plantable preparations - Dr. Pál Szilárd
• 27. Written test - Dr. Pál Szilárd
• 28. Written test - Dr. Pál Szilárd

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

Notes

Recommended literature

European Pharmacopoeia
Formulae Normales VII. (FoNo VII.)
James Swarbrick: Encyclopedia of Pharmaceutical Technology, Informa Healthcare, New York, London
Gilbert S. Banker, Christopher T. Rhodes: Modern Pharmaceutics, Marcel Dekker Inc., New York- Basel
Chris Langley, Dawn Belcher: Pharmaceutical Compounding and Dispensing, Pharmaceutical Press
www.gytk.pte.hu
www.sciencedirect.com
Attila Dévay: The Theory and Practice of Pharmaceutical Technology, electronic book, PTE-Pécs
Attila Dévay: Investigation of Pharmaceutical Preparations, electronic book, PTE-Pécs

Conditions for acceptance of the semester

Code of Studies and Regulations

Mid-term exams

Students have to write three assessments during the semester and they have to reach 60 % after average calculation. After two assessments if students reach average 60 % taking into account both tests, writing the third assesment it not compulsory. The third assessments (which is considered as the 1st retake) has to above 60,1 %. If the student fails on the 3rd assessment, there is still chance for the 2nd retake, where student has to reach 60,1% for the acceptance of the semester. In case of confirmed absence from the assessment, re-take chance is sossible for the student. Missing the re-take results 0 % assessment.

Making up for missed classes

Students must fulfil requirements determined by the Code of Studies and Examinations.

Exam topics/questions

The criterion of admission to the exam is the successful completion of the Pharm. Tech . 1. practice.
The end-semester exam will be evaluated by a five-grade system. Knowledge acquired is tested based on subject matter defined by a list of topics provided by the institute.The end-semester exam will be evaluated by a five-grade system.
Knowledge acquired is tested based on subject matter defined by a list of topics provided by the institute.
At the end of semester, students take oral exam. Chance "B"and "C" are also oral exams, which is preceded by the "Minimum Test"(MT). To write the MT, students have at most 30 minutes, and will be evaluated percent rating. Those students, who achieve less than 60% in MT, unsatisfactory grade will be assessed and cannot pass them to the oral part of the exam.
Oral part includes two topics. In the case of any part done with insufficient knowledge, will result in assessment of the exam to unsatisfactory grade.

In addition to the exam topics, part of the exam is answering questions that aim at assessing the general knowledge of the student.

Examiners

• Ámanné Dr. Takácsi-Nagy Anna Erzsébet
• Dr. Dévay Attila
• Dr. Kása Péter
• Dr. Pál Szilárd

Instructor / tutor of practices and seminars