Biochemistry II

Data

Official data in SubjectManager for the following academic year: 2026-2027

Topic

Biochemistry II is built on the already known energy providing and biosynthetic pathways. We will study the metabolic regulations at different levels: cellular, tissues and whole organism. This means the most important information about enzymes and hormones: their synthesis and mechanisms of action. Especially enzymes are the subject of biotechnology: they are products as well as tools. Considering the human body, we discuss the energy supplies in fasting, sport, work, and also the most frequent pathobiochemical situations (diabetes mellitus). Special subject is the transmembrane processes, which are the targets of a large number of drugs.

Lectures

• 1.

  Amino acids

  - Farkas Viktória
• 2.

  Synthesis of nucleotides

  - Farkas Viktória
• 3.

  Ketone bodies

  - Farkas Viktória
• 4.

   Citric acid cycle, anaplerotic reactions

  - Sipos Katalin
• 5.

  Cholesterol metabolism

  - Farkas Viktória
• 6.

  Biosynthesis of fatty acids

  - Farkas Viktória
• 7.

  Amino acid synthesis

  - Farkas Viktória
• 8.

  Urea cycle

  - Sipos Katalin
• 9.

  Neurotransmitters

  - Sipos Katalin
• 10.

  Role of the liver in metabolism

  - Sipos Katalin
• 11.

  Development of drugs

  - Pandur Edina
• 12. Metabolism of drugs - Sipos Katalin
• 13.

  Genetic diseases of metabolism

  - Sipos Katalin
• 14.

  Consultation

  - Farkas Viktória

Practices

• 1.

  Lysing cells, protein concentration,

  acrylamide gel

  - Jánosa Gergely
• 2.

  Lysing cells, protein concentration,

  acrylamide gel

  - Jánosa Gergely
• 3.

  Electrophoresis and Western blotting

  - Jánosa Gergely
• 4.

  Electrophoresis and Western blotting

  - Jánosa Gergely
• 5.

  LDH

  - Tamási Kitti
• 6.

  LDH

  - Tamási Kitti
• 7.

  ALP, enzyme inhibition

  - Tamási Kitti
• 8.

  ALP, enzyme inhibition

  - Tamási Kitti
• 9.

  Cholesterol level in blood

  - Farkas Viktória
• 10.

  Cholesterol level in blood

  - Farkas Viktória
• 11.

  Blood uric acid level

  - Tamási Kitti
• 12.

  Blood uric acid level

  - Tamási Kitti
• 13.

  Vitamins

  - Jánosa Gergely
• 14.

  Hormones

  - Farkas Viktória
• 15.

  Starvation-fed state

  - Farkas Viktória
• 16.

  Muscle, brain, kidney, sport, pregnancy

  - Jánosa Gergely
• 17.

  Regulation of cholesterol and glycogen

  - Farkas Viktória
• 18.

  Regulation of glycolysis and gluconeogenesis

  - Farkas Viktória
• 19.

  Midterm exam of the practice

  - Farkas Viktória
• 20.

  Midterm exam of the practice

  - Farkas Viktória
• 21.

  HPLC

  - Böddi Katalin
• 22.

  HPLC

  - Böddi Katalin
• 23.

  Toxicology - determination of ethanol level in blood

  - Poór Viktor Soma
• 24.

  3D techniques in Forensic medicine

  - Poór Viktor Soma
• 25.

  Institute of Laboratory Medicine - human samples for diagnosis, automated systems in a laboratory

  - Dolmán Veronika
• 26.

  Institute of Laboratory Medicine - human samples for diagnosis, automated systems in a laboratory

  - Dolmán Veronika
• 27.

  Consultation

  - Farkas Viktória
• 28.

  Consultation

  - Farkas Viktória

Seminars

• 1.

  Structure and purification of proteins

  - Pandur Edina
• 2.

  Degradation of nucleotides

  - Farkas Viktória
• 3.

  Energy production in plants

  - Pandur Edina
• 4.

  Terminal oxidation, ATP synthesis

  - Farkas Viktória
• 5.

  Clinical importance of terminal oxidation

  - Farkas Viktória
• 6.

  Biomembranes

  - Jánosa Gergely
• 7.

  Amino acid degradation

  - Farkas Viktória
• 8.

  Diabetes mellitus

  - Farkas Viktória
• 9.

  Metabolism of alcohol

  - Farkas Viktória
• 10.

  Regulation of citric acid cycle, terminal oxidation

  - Sipos Katalin
• 11.

  Drugs in biotechnology

  - Pandur Edina
• 12.

  Lipids - summary

  - Sipos Katalin
• 13.

  Carbohydrates - summary

  - Sipos Katalin
• 14.

  Consultation

  - Farkas Viktória

Reading material

Obligatory literature

Literature developed by the Department

The materials of the lectures and seminars will appear on Neptune.

Notes

Recommended literature

Ch. P. Woodbury: Biochemistry for the Pharmaceutical Sciences

Raymond S. Ochs: Biochemistry

Thomas M. Devlin: Textbook of Biochemistry with Clinical Correlations

Conditions for acceptance of the semester

There are no other terms of acceptance.

Mid-term exams

There is no written mid-term exam in the semester.

Making up for missed classes

According to personal agreement

Exam topics/questions

There are no given exam questions. The topics of the writtenexam will be the materials of lectures and seminars. There essay questions in the final exam about known topics.

Examiners

• Farkas Viktória
• Pandur Edina
• Sipos Katalin

Instructor / tutor of practices and seminars

• Böddi Katalin
• Dolmán Veronika
• Farkas Viktória
• Jánosa Gergely
• Pandur Edina
• Poór Viktor Soma
• Sipos Katalin
• Tamási Kitti