Biochemistry I

Data

Official data in SubjectManager for the following academic year: 2024-2025

Topic

In the Biochemistry I subject, the students will study the macromolecules, which build up the eukaryotic cells. They learn about the most important energy providing pathways (glycolysis, citric acid cycle, fatty acid degradation, photosynthesis), and the major biosynthetic pathways (glycogen, lipid, amino acid and nucleotide synthesis). In addition, we will deal with the basic biochemistry of prokaryotic and plant cells, as they are widely used in biotechnology.

Lectures

• 1. Introduction. Metabolic pathways - Sipos Katalin
• 2. Glycolysis - Sipos Katalin
• 3. Gluconeogenesis. Cori cycle - Farkas Viktória
• 4. Metabolism of glycogen - Farkas Viktória
• 5. Pyruvate dehydrogenase complex - Farkas Viktória
• 6. Pentose phosphate pathway - Pap Ramóna
• 7. Degradation of fatty acids - Sipos Katalin
• 8. Citric acid cycle - Sipos Katalin
• 9. Terminal oxidation, ATP synthesis - Farkas Viktória
• 10. Ketone bodies - Farkas Viktória
• 11. Biosynthesis of fatty acids - Farkas Viktória
• 12. Metabolism of cholesterol - Farkas Viktória
• 13. Amino acids - Pap Ramóna
• 14. Nucleic acids: building blocks, structure - Pap Ramóna

Practices

Seminars

• 1. Basic regulatory processes of metabolism - Jánosa Gergely
• 2. Thermodynamics, biochemical reactions - Jánosa Gergely
• 3.

  Carbohydrates

  - Farkas Viktória
• 4.

  Carbohydrates

  - Farkas Viktória
• 5. Enzymology - the basics - Sipos Katalin
• 6. Enzyme kinetics - Sipos Katalin
• 7. Inhibition of enzymes - Sipos Katalin
• 8. Regulation of enzymes - Sipos Katalin
• 9. Enzymes in biotechnology - Pandur Edina
• 10. Enzymes in biotechnology - Pandur Edina
• 11.

  Importance of carbohydrates in biotechnology

  - Pap Ramóna
• 12. Metabolism of complex carbohydrates - Farkas Viktória
• 13. Lipids - Jánosa Gergely
• 14. Importance of lipids in biotechnology. - Jánosa Gergely
• 15. Anaplerotic processes. - Farkas Viktória
• 16. Metabolism of complex lipids. - Sipos Katalin
• 17. Clinical importance of terminal oxidation. - Farkas Viktória
• 18. Carbohydrates – summary. - Sipos Katalin
• 19.

  Energy production in plants.

  - Pandur Edina
• 20.

  Carbohydrate metabolism in plants.

  - Pandur Edina
• 21. Energy production in bacteria - Jánosa Gergely
• 22. Energy production in bacteria - Jánosa Gergely
• 23. Lipids, energy production – summary - Sipos Katalin
• 24. Lipids, energy production – summary - Sipos Katalin
• 25. Structure of proteins. - Pandur Edina
• 26. Purification of proteins. - Pandur Edina
• 27. Consultation - Sipos Katalin
• 28. Consultation - Sipos Katalin

Reading material

Obligatory literature

Literature developed by the Department

The materials of the lectures and seminars will appear on Neptune.

Notes

Recommended literature

Ch. P. Woodbury: Biochemistry for the Pharmaceutical Sciences

Raymond S. Ochs: Biochemistry

Thomas M. Devlin: Textbook of Biochemistry with Clinical Correlations

Conditions for acceptance of the semester

There are no other terms of acceptance.

Mid-term exams

There is no written mid-term exam in the semester.

Making up for missed classes

According to personal agreement

Exam topics/questions

There are no given exam questions. The topics of the exam will be the materials of lectures and seminars.

Examiners

• Farkas Viktória
• Pandur Edina
• Sipos Katalin

Instructor / tutor of practices and seminars

• Farkas Viktória
• Jánosa Gergely
• Pandur Edina
• Pap Ramóna
• Sipos Katalin