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Molecular biology of cancer

Data

Official data in SubjectManager for the following academic year: 2026-2027

Course director

Number of hours/semester

lectures: 24 hours

practices: 0 hours

seminars: 0 hours

total of: 24 hours

Subject data

  • Code of subject: OAE-DMO-T
  • 2 kredit
  • General Medicine
  • Elective modul
  • spring semester
Prerequisites:

OAA-MB1-T finished

Course headcount limitations

min. 5 – max. 200

Available as Campus course for . Campus-karok: GYTK TTK

Topic

The course examines the genetic, epigenetic, and cellular mechanisms underlying tumorigenesis, with particular emphasis on the dysregulation of signaling networks and the functional consequences of oncogene and tumor suppressor gene mutations. Students will gain insight into the interactions among molecular mechanisms, their network-level organization, and their clinical relevance. Special attention is given to recent advances in the field, the role of the tumor microenvironment, molecular heterogeneity, and the mechanistic basis of targeted and precision therapies. The course aims to enable students to interpret the complex processes of cancer development from a systems-level perspective and to apply the acquired knowledge in their further studies.

Lectures

  • 1. General characteristics of tumors - Pap Marianna
  • 2. General characteristics of tumors - Pap Marianna
  • 3. The role of intracellular receptor-mediated signal transduction in hormone-dependent tumors - Pap Marianna
  • 4. The role of intracellular receptor-mediated signal transduction in hormone-dependent tumors - Pap Marianna
  • 5. The role of cell surface receptor-mediated signal transduction processes in tumor formation - Pap Marianna
  • 6. The role of cell surface receptor-mediated signal transduction processes in tumor formation - Pap Marianna
  • 7. The role of apoptosis signal transduction processes in tumor formation - Pap Marianna
  • 8. The role of apoptosis signal transduction processes in tumor formation - Pap Marianna
  • 9. The role of DNA tumor viruses in tumor formation - Pap Marianna
  • 10. The role of DNA tumor viruses in tumor formation - Pap Marianna
  • 11. The role of RNA tumor viruses in tumor formation - Pap Marianna
  • 12. The role of RNA tumor viruses in tumor formation - Pap Marianna
  • 13. The role of gain-of-function mutations in tumor formation - Pap Marianna
  • 14. The role of gain-of-function mutations in tumor formation - Pap Marianna
  • 15. The role of loss-of-function mutations in tumor formation - Pap Marianna
  • 16. The role of loss-of-function mutations in tumor formation - Pap Marianna
  • 17. Molecular model of multistep carcinogenesis - Pap Marianna
  • 18. Molecular model of multistep carcinogenesis - Pap Marianna
  • 19. Clinical model of multistep carcinogenesis - Pap Marianna
  • 20. Clinical model of multistep carcinogenesis - Pap Marianna
  • 21. Therapeutic targets and targeted therapies - Pap Marianna
  • 22. Therapeutic targets and targeted therapies - Pap Marianna
  • 23. Test - Pap Marianna
  • 24. Test - Pap Marianna

Practices

Seminars

Reading material

Obligatory literature

Literature developed by the Department

Lectures ppt presentations

Notes

Recommended literature

Conditions for acceptance of the semester

-

Mid-term exams

-

Making up for missed classes

no possibility for make up

Exam topics/questions

-

Examiners

Instructor / tutor of practices and seminars

Rólunk