Chemistry for Dentistry Students

Data

Official data in SubjectManager for the following academic year: 2020-2021

Topic

Medical chemistry includes the topics of general chemistry which are necessary for medical students. It deals also with the chemistry of organic functional groups in concise way. Majority of the curriculum deals with the bioorganic chemistry, which means the chemistry and descriptive biochemistry of biomolecules. The purpose of practices is to study some analytical chemistry and the knowledge of materials. Curriculum of medical chemistry contains the basic knowledge that is necessary to understand biochemistry.

Lectures

• 1. Introduction to Medical Chemistry, its relationship with medicine. - Dr. Jakus Péter Balázs
• 2. The periodic table, the electronic structure of atoms. - Dr. Nagy Veronika
• 3. Chemical bonds. Ionic, covalent and metallic bond - Dr. Nagy Veronika
• 4. Chemical bonds. Basics of MO and VB theories. - Dr. Nagy Veronika
• 5. Secondary interactions. - Dr. Nagy Veronika
• 6. Chemistry, types and properties of the elements. - Dr. Berente Zoltán
• 7. Oxides, hydroxides, acids, bases and salts. - Dr. Berente Zoltán
• 8. States of matter, gas laws. - Dr. Takátsy Anikó
• 9. Water and aqueous solutions. Colligative properties of dilute solutions. Composition of biofluids - Dr. Takátsy Anikó
• 10. Role of electrolytes in living organisms - Dr. Berente Zoltán
• 11. Chemical equilibrium, mass action law - Dr. Lóránd Tamás
• 12. Heterogeneous equilibria. Solubility product constant. Gallstones and kidney stones - Dr. Lóránd Tamás
• 13. Acids and bases - Dr. Lóránd Tamás
• 14. Ion product constant of water, pH, pOH - Dr. Lóránd Tamás
• 15. Hydrolysis of salts. Buffer solutions. - Dr. Lóránd Tamás
• 16. Buffer systems in living organisms - Dr. Berente Zoltán
• 17. Structure and formation of complexes. - Dr. Agócs Attila
• 18. Metal complexes in living organisms and in medical diagnosis - Dr. Agócs Attila
• 19. Colloid systems - Dr. Jakus Péter Balázs
• 20. Colloid systems in living organisms - Dr. Jakus Péter Balázs
• 21. Chemical kinetics - Dr. Jakus Péter Balázs
• 22. Thermodynamics: Energy changes in chemical reactions - Dr. Jakus Péter Balázs
• 23. Thermodynamics: spontaneous and non-spontaneous reactions - Dr. Jakus Péter Balázs
• 24. Photochemistry. Light induced reactions in living organisms - Dr. Jakus Péter Balázs
• 25. Electrochemistry - Dr. Berente Zoltán
• 26. Electron transfer processes in living organisms - Dr. Berente Zoltán
• 27. Introduction to organic chemistry - Dr. Agócs Attila
• 28. Reaction types in organic chemistry - Dr. Agócs Attila
• 29. Saturated hydrocarbons: Alkanes. Paraffins in medicine - Dr. Lóránd Tamás
• 30. Unsaturated hydrocarbons: Alkenes and alkynes - Dr. Lóránd Tamás
• 31. Isomerism among alkanes, cycloalkanes and alkenes - Dr. Lóránd Tamás
• 32. Aromatic hydrocarbons. Organic halides - Dr. Lóránd Tamás
• 33. Optical isomerism. Relative and absolute configuration. - Dr. Agócs Attila
• 34. Alcohols - Dr. Lóránd Tamás
• 35. Phenols - Dr. Lóránd Tamás
• 36. Ethers - Dr. Lóránd Tamás
• 37. Organic thio compounds - Dr. Lóránd Tamás
• 38. Aldehydes and their derivatives - Dr. Agócs Attila
• 39. Ketones, quinones - Dr. Agócs Attila
• 40. Amines and their biologically relevant derivatives - Dr. Lóránd Tamás
• 41. Carboxylic acids - Dr. Lóránd Tamás
• 42. Carboxylic esters, phosphate esters and sulphate esters - Dr. Lóránd Tamás

Practices

• 1. Laboratory regulations. Accident and fire protection
• 2. Laboratory regulations. Accident and fire protection
• 3. Introductory discussion
• 4. Introductory discussion
• 5. Experiments with compounds of halogens, oxygen-group and nitrogen group elements
• 6. Experiments with compounds of halogens, oxygen-group and nitrogen group elements
• 7. Experiments with compounds of carbon-group, aluminium and s-block elements
• 8. Experiments with compounds of carbon-group, aluminium and s-block elements
• 9. Discussion
• 10. Discussion
• 11. Titration of Betacid solution
• 12. Titration of Betacid solution
• 13. Potentiometry. Buffer solutions.
• 14. Potentiometry. Buffer solutions.
• 15. Reactions of coordinative (complex) compounds.
• 16. Reactions of coordinative (complex) compounds.
• 17. Experiments on colloidal systems, chemical equilibria, and catalysis
• 18. Experiments on colloidal systems, chemical equilibria, and catalysis
• 19. Experiments in electrochemistry
• 20. Experiments in electrochemistry
• 21. Organic chemistry I. Reactions of functional groups I
• 22. Organic chemistry I. Reactions of functional groups I
• 23. Organic chemistry I. Reactions of functional groups II
• 24. Organic chemistry I. Reactions of functional groups II
• 25. Organic chemistry I. Reactions of functional groups III
• 26. Organic chemistry I. Reactions of functional groups III
• 27. Closing remarks, repetition
• 28. Closing remarks, repetition

Seminars

• 1. Basic concepts, stoichiometric calculations
• 2. Stoichiometric calculations
• 3. Geometry and polarity of molecules. Intermolecular interactions
• 4. Concentration of solutions
• 5. Structure of simple organic molecules
• 6. Naming organic molecules. Isomerism
• 7. Structure and properties of various types of organic compounds
• 8. Stereochemistry I. Chirality, enantiomers
• 9. Stereochemistry II: Diastereomers
• 10. Reactions in organic chemistry I: Types of reactions
• 11. Reactions in organic chemistry II:Alkenes and aromatic compounds
• 12. Reactions in organic chemistry III:Alcohols
• 13. Reactions in organic chemistry IV:Aldehydes and ketones
• 14. Reactions in organic chemistry V:Carboxylic acids

Reading material

Obligatory literature

P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, latest edition, Univ. Med. School of Debrecen

Literature developed by the Department

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Notes

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Recommended literature

Veronika Nagy (ed.): Laboratory Experiments in Medical Chemistry, Internet edition, Univ. Med. School of Pécs, 2011
Hein-Pattison-Arena-Best: Introduction to Chemistry General, Organic, and Biochemistry, latest edition
P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, latest edition, Univ. Med. School of Debrecen

Conditions for acceptance of the semester

Maximum of 15 % absence allowed

Mid-term exams

During weeks 3-14 of the semester there are short tests at the beginning of each practice. Additional requirement for acceptance is writing 10 out of these 12 tests, and minimum 7 out of them should be correct and accepted by the lab instructor. It is obligatory to write lab-notes. Result of the short test is acknowledged only if the lab-note of the practice is accepted by the lab instructor.

Making up for missed classes

2 absences are allowed from the 14 occasions of lab and seminar practices.
The semester is not accepted if the student has more than 2 absences. If the student is late more than 5 minutes he/she can not write lab test. If the student is late 5-10 minutes, he/she may perform the lab experiments and this occasion will not be considered as an absence. Less than 5 minutes late is accepted. More than 10 minutes late is absence.
The lab and seminar classes cannot be made up.

Exam topics/questions

The exam is based on the topic of the lectures and labs. The lectures are identical with the General Medicine program.
http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Examiners

• Dr. Bognár Zita
• Dr. Bóna Ágnes
• Dr. Jakus Péter Balázs

Instructor / tutor of practices and seminars

• Dr. Jakus Péter Balázs