Data
Official data in SubjectManager for the following academic year: 2024-2025
Course director
-
Debreceni Balázs
associate professor,
Department of Biochemistry and Medical Chemistry -
Number of hours/semester
lectures: 42 hours
practices: 28 hours
seminars: 14 hours
total of: 84 hours
Subject data
- Code of subject: OSA-ORF-T
- 6 kredit
- Dentistry
- Basic modul
- autumn
-
Course headcount limitations
min. 5 – max. 200
Topic
Medical chemistry includes the topics of general chemistry which are necessary for medical students. It deals also with the chemistry of organic functional groups in concise way. Majority of the curriculum deals with the bioorganic chemistry, which means the chemistry and descriptive biochemistry of biomolecules. The purpose of practices is to study some analytical chemistry and the knowledge of materials. Curriculum of medical chemistry contains the basic knowledge that is necessary to understand biochemistry.
Lectures
- 42. Colloids found in living systems - Berente Zoltán
- 40. Amines and their biologically significant derivatives - Balogi Zsolt
- 41. Colloids - Berente Zoltán
- 39. Organic sulfur compounds, thioesters - Böddi Katalin
- 37. Carboxylic acids - Böddi Katalin
- 38. Carboxylic acid derivatives, acylating agents - Böddi Katalin
- 36. Aldehydes and their derivatives - Böddi Katalin
- 35. Phenols, quinones, ethers - Nagy Veronika
- 34. Alcohols, enols, esters (including phosphate and sulphate esters) - Nagy Veronika
- 33. Optical isomerism. Relative and absolute configuration. - Nagy Veronika
- 31. Unsaturated hydrocarbons: Alkenes and alkynes - Nagy Veronika
- 32. Constitutional, conformational and geometric isomerism - Nagy Veronika
- 30. Saturated hydrocarbons: Alkanes. Paraffins in medicine - Nagy Veronika
- 29. Reaction types in organic chemistry - Bognár Zita
- 28. Analitical instruments in medical diagnostics - Berente Zoltán
- 27. Basics of separation thechniques for medical students - Takátsy Anikó
- 25. Electrochemistry in the medical practice - Berente Zoltán
- 26. Basics of analytical chemistry for medical students - Takátsy Anikó
- 24. Electron transfer processes in living organisms - Berente Zoltán
- 23. Electrochemistry - Nagy Veronika
- 22. Kinetic characteristics of cascade- and cyclic reactions - Nagy Veronika
- 21. Steady-stateness, a characteristic of living systems - Nagy Veronika
- 20. Reactionkinetics - Nagy Veronika
- 19. Thermodynamics applied to living systems - Nagy Veronika
- 18. Thermodynamics and the direction of chemical reactions - Takátsy Anikó
- 17. Thermochemistry - Berente Zoltán
- 16. Metal complexes in living organisms and in medical diagnosis - Takátsy Anikó
- 14. Buffer systems in living organisms - Takátsy Anikó
- 15. Structure and formation of metal complexes. - Berente Zoltán
- 13. Buffer solutions - Takátsy Anikó
- 12. Ion product constant of water, pH, pOH, hydrolysis of salts, pH-dependence of protonation - Takátsy Anikó
- 11. Acids and bases, acid-base theories, acid-base reactions - Takátsy Anikó
- 10. Role of electrolytes in living organisms, solubilty - Takátsy Anikó
- 9. Equilibrium, the law of mass action, Le Chatelier principle - Berente Zoltán
- 8. Osmosis, composition of biofluids - Gallyas Ferenc
- 7. Water and aqueous solutions. Concentration units. Colligative properties of dilute solutions. - Bóna Ágnes
- 6. States of matter, gas laws. - Nagy Veronika
- 5. Introduction to organic chemistry. Nomenclatute, functional groups, Reaction types - Nagy Veronika
- 4. Molecular geometry, polarity, molecular interactions - Nagy Veronika
- 3. Intrduction to inorganic chemistry. Oxides, oxoacids, hydroxides, salts - Nagy Veronika
- 2. Structure of matter (atoms, ions, molecules, radicals) - Nagy Veronika
- 1. Introduction to Medical Chemistry - Bognár Zita
Practices
- 1. Laboratory regulations. Accident and fire protection
- 2. Laboratory regulations. Accident and fire protection
- 3. Introductory discussion
- 4. Introductory discussion
- 5. Experiments with compounds of halogens, oxygen-group and nitrogen group elements
- 6. Experiments with compounds of halogens, oxygen-group and nitrogen group elements
- 7. Experiments with compounds of carbon-group, aluminium and s-block elements
- 8. Experiments with compounds of carbon-group, aluminium and s-block elements
- 9. Discussion
- 10. Discussion
- 11. Titration of Betacid solution
- 12. Titration of Betacid solution
- 13. Potentiometry. Buffer solutions.
- 14. Potentiometry. Buffer solutions.
- 15. Reactions of coordinative (complex) compounds.
- 16. Reactions of coordinative (complex) compounds.
- 17. Experiments on colloidal systems, chemical equilibria, and catalysis
- 18. Experiments on colloidal systems, chemical equilibria, and catalysis
- 19. Experiments in electrochemistry
- 20. Experiments in electrochemistry
- 21. Organic chemistry I. Reactions of functional groups I
- 22. Organic chemistry I. Reactions of functional groups I
- 23. Organic chemistry I. Reactions of functional groups II
- 24. Organic chemistry I. Reactions of functional groups II
- 25. Organic chemistry I. Reactions of functional groups III
- 26. Organic chemistry I. Reactions of functional groups III
- 27. Closing remarks, repetition
- 28. Closing remarks, repetition
Seminars
- 1. Basic concepts, stoichiometric calculations
- 2. Stoichiometric calculations
- 3. Geometry and polarity of molecules. Intermolecular interactions
- 4. Concentration of solutions
- 5. Structure of simple organic molecules
- 6. Naming organic molecules. Isomerism
- 7. Structure and properties of various types of organic compounds
- 8. Stereochemistry I. Chirality, enantiomers
- 9. Stereochemistry II: Diastereomers
- 10. Reactions in organic chemistry I: Types of reactions
- 11. Reactions in organic chemistry II:Alkenes and aromatic compounds
- 12. Reactions in organic chemistry III:Alcohols
- 13. Reactions in organic chemistry IV:Aldehydes and ketones
- 14. Reactions in organic chemistry V:Carboxylic acids
Reading material
Obligatory literature
P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, latest edition, Univ. Med. School of Debrecen
Literature developed by the Department
http://aok.pte.hu/en/egyseg/oktatasianyagok/2020
Notes
http://aok.pte.hu/en/egyseg/oktatasianyagok/2020
Recommended literature
Veronika Nagy (ed.): Laboratory Experiments in Medical Chemistry, Internet edition, Univ. Med. School of Pécs, 2011
Hein-Pattison-Arena-Best: Introduction to Chemistry General, Organic, and Biochemistry, latest edition
P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, latest edition, Univ. Med. School of Debrecen
Conditions for acceptance of the semester
no other requirements
Mid-term exams
Each week's practice scripts include questions that can be found in advance in the workbook. From the 3rd week, students write a small test at the beginning of the practice. Questions will be asked for written answers, with 6 minutes available for the answers. Those who do not take the test during the internship will automatically receive 0 points for this week. With the tests you can get bonus points for the exam. (max. 5 points). The points collected here do not apply to passing the minimum questions, but are added to the final exampoints as extra points. The result of the small test is only valid after the group leader has accepted the protocol booklet. The examination is a colloquium, the questions must be answered and explained in writing. The exam starts with 10 minimum questions.
Making up for missed classes
2 absences are allowed from the 14 occasions of lab and seminar practices.
The semester is not accepted if the student has more than 2 absences. If the student is late more than 5 minutes he/she can not write lab test. If the student is late 5-10 minutes, he/she may perform the lab experiments and this occasion will not be considered as an absence. Less than 5 minutes late is accepted. More than 10 minutes late is absence.
The lab and seminar classes cannot be made up.
Exam topics/questions
The exam is based on the topic of the lectures and labs. It is a written exam, includes 10 MRT questions. MRT questions, 30 points, must be obtained at least 21 points. If less than 21 points is obtained from the MRT questions the exam is failed, irrespectively of the remaining part of the test and the brought extra points. Main questions 11–: 90 points;
Total: 120 points +Laboratory test points (maximum 5)
Scores and grades:
0–70: 1
71–80: 2
81–90: 3
91–100: 4
101– : 5 Detailed information: http://aok.pte.hu/en/egyseg/oktatasianyagok/2020
http://aok.pte.hu/en/egyseg/oktatasianyagok/20
Examiners
- Bognár Zita
- Bóna Ágnes
- Debreceni Balázs
Instructor / tutor of practices and seminars
- Andreidesz Kitti
- Bóna Ágnes