Introduction to Biochemistry

Data

Official data in SubjectManager for the following academic year: 2024-2025

Topic

Introduction to Biochemistry includes the topics of organic and bioorganic chemistry along with basic biochemistry which are necessary for medical students. It deals with the structure, chemistry, and cellular degradation of essential biomolecules like proteins, carbohydrates and lipids. The purpose of practices is to study some analytical chemistry and the knowledge of materials. Curriculum of medical chemistry contains the basic knowledge that is necessary to understand biochemistry, pharmacology and clinical chemistry.

Lectures

• 1. Introduction - Veres Balázs
• 2. Carbonic acid derivatives, Heterocycles I. - Gulyás Gergely
• 3. Heterocycles II. - Gulyás Gergely
• 4. Alkaloids - Nagy Veronika
• 5. Structure of carbohydrates - Nagy Veronika
• 6. Reactivity of carbohydrates - Nagy Veronika
• 7. Di-, oligo- and polysaccharides - Nagy Veronika
• 8. Composition of simple and complex lipids - Balogi Zsolt
• 9.

  Prostaglandins, terpenoids

  - Böddi Katalin
• 10. Steroids - Takátsy Anikó
• 11.

  Amino acids, peptides

  - Jávor-Hocsák Enikő
• 12.

  Protein structure

  - Andreidesz Kitti
• 13. Hemoglobin, oxygen transport - Takátsy Anikó
• 14. Myosin, Ig, scaffold proteins - Takátsy Anikó
• 15. Bioenergetics, koenzymes - Berente Zoltán
• 16. Basics of enzyme kinetics - Berente Zoltán
• 17. Regulation of enzymatic activity, isoenzymes - Berente Zoltán
• 18. Characterization of biological membranes - Takátsy Anikó
• 19. Membrane transports - Takátsy Anikó
• 20.

  Nucleosides, nucleotides

  - Bóna Ágnes
• 21.

  Nucleic acids

  - Bóna Ágnes
• 22. DNA I. Replication - Veres Balázs
• 23. DNA II. Repair mechanisms - Veres Balázs
• 24. RNA I. Transcription - Veres Balázs
• 25. RNA II. Post-transcriptional modifications - Veres Balázs
• 26. Proteins I. Translation - Takátsy Anikó
• 27. Proteins II. Translation - Takátsy Anikó
• 28. Proteins III. Regulation - Takátsy Anikó

Practices

• 1. Basics of bioorganic chemistry
• 2. Basics of bioorganic chemistry
• 3. Stereochemistry
• 4. Stereochemistry
• 5. Heterocycles
• 6. Heterocycles
• 7. Isolation of caffeine
• 8. Isolation of caffeine
• 9. Properties of carbohydrates
• 10. Properties of carbohydrates
• 11. Properties of lipids
• 12. Properties of lipids
• 13. Proteins
• 14. Proteins
• 15. Biuret
• 16. Biuret
• 17. Amino acid titration
• 18. Amino acid titration
• 19. Enzymes I.
• 20. Enzymes I.
• 21. Enzymes II.
• 22. Enzymes II.
• 23. Warburg optical test
• 24. Warburg optical test
• 25. Molecular biology
• 26. Molecular biology
• 27. Consultation
• 28. Consultation

Seminars

Reading material

Obligatory literature

Nelson, Cox: Lehninger Principles of Biochemistry, 5th ed., W.H. Freeman, 2008 http://bcs.whfreeman.com/lehninger5e

Berg, Tymoczko, Stryer: Biochemistry, 7th ed. http://bcs.whfreeman.com/berg7e

McMurray, Fay: Chemistry, latest edition

Darrell D. Ebbing (ed.): General Chemistry, latest edition

P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, Univ. Med. School of Debrecen

K. C. Timberlake: Chemistry - An Introduction to General, Organic and Biological Chemistry, latest edition

Literature developed by the Department

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Notes

Veronika Nagy (ed.): Laboratory Experiments in Medical Chemistry, Internet edition, Univ. Med. School of Pécs, 2011

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Recommended literature

Conditions for acceptance of the semester

Requirement for acceptance of Introduction to biochemistry (i.e. signature): during weeks 3-14 of the semester there are short tests at the beginning of each practice. Students have to write 10 out of these 12 tests, and at least 7 out of them should be correct and accepted by the lab instructor. It is obligatory to write lab-notes. The result of the short test is acknowledged only if the lab-note of the practice is accepted by the lab instructor.

Further details are on the webpage of the Department.

Mid-term exams

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Making up for missed classes

None.

Exam topics/questions

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Examiners

• Agócs Attila
• Andreidesz Kitti
• Balogi Zsolt
• Berente Zoltán
• Böddi Katalin
• Bóna Ágnes
• Gelencsér Andrásné (Gitta Stefánia)
• Gulyás Gergely
• Jakus Péter Balázs
• Linzembold Ildikó Erzsébet
• Nagy Veronika
• Nagyné Kiss Gyöngyi
• Radnai Balázs (Biokémia)
• Szabó Éva (Biokémia)
• Szilágyi Tamás Gábor
• Takátsy Anikó
• Veres Balázs

Instructor / tutor of practices and seminars

• Berente Zoltán
• Böddi Katalin
• Gulyás Gergely
• Jakus Péter Balázs
• Linzembold Ildikó Erzsébet
• Nagy Veronika
• Nagyné Kiss Gyöngyi
• Szilágyi Tamás Gábor
• Takátsy Anikó