Data
Official data in SubjectManager for the following academic year: 2026-2027
Course director
-
Melegh Szilvia Zsóka
assistant professor,
Department of Medical Microbiology and Immunology -
Number of hours/semester
lectures: 28 hours
practices: 0 hours
seminars: 0 hours
total of: 28 hours
Subject data
- Code of subject: OPO-MI1-T
- 2 kredit
- Pharmacy
- Pharmaceutical Science and Pharmacy modul
- autumn semester
OPO-G1B-T finished , OPO-G2B-T finished
Course headcount limitations
min. 1 – max. 999
Topic
The objective of this course is to provide students with fundamental knowledge about microorganisms, which is essential for understanding antimicrobial therapy, vaccination, sterilization and disinfection procedures. A key component of the curriculum is antibiotic therapy, covering the mechanisms of action, spectrum of activity, pharmacodynamics, and pharmacokinetics of the most significant antibiotic groups. The issue of antimicrobial resistance and its global health impacts are discussed in detail. Proficiency in sterilization and disinfection procedures, as well as the microbiological purity control of pharmaceutical products, is indispensable for pharmacy students, forming the basis of patient safety and a secure drug supply. Furthermore, students learn about the immunological background of infectious diseases and the fundamental principles of vaccinations and immunotherapy. The course also involves a part of systematic bacteriology, where therapeutic and preventive options for specific pathogens are discussed in details. By gaining comprehensive knowledge of antimicrobial agents and vaccines, pharmacy students will be equipped to provide reliable patient information and engage in pharmaceutical research. Ultimately, this prepares them for an active role in the treatment and prevention of infectious diseases.
Lectures
- 1.
Introduction; The subject of microbiology, Taxonomy
- Melegh Szilvia Zsóka - 2. Morphology and structure of bacteria - essential cell components - Tigyi Zoltán
- 3. Morphology and structure of bacteria - accessorial cell components - Tigyi Zoltán
- 4. The physiology of bacteria, nutrition types and growth of bacteria - Kocsis Béla
- 5. Microbial genetics - Tigyi Zoltán
- 6.
Pathogenicity and virulence. Virulence factors
- Tigyi Zoltán - 7.
Sterilization
- Melegh Szilvia Zsóka - 8.
Disinfection
- Melegh Szilvia Zsóka - 9. Microbiological evaluation of drugs. Pyrogenicity testing - Kocsis Béla
- 10.
Antimicrobial chemotherapy - basic principles. Pharmacodynamic and pharmacokinetic effects
- Zsoldiné Urbán Edit - 11. Inhibitors of bacterial cell wall synthesis I - Zsoldiné Urbán Edit
- 12. Inhibitors of bacterial cell wall synthesis II.; Membran targeting drugs - Zsoldiné Urbán Edit
- 13. Inhibitors of protein synthesis I - Zsoldiné Urbán Edit
- 14.
Inhibitors of protein synthesis II, Chemotherapy: sulfonamides, quinolones, nitrofurans
- Zsoldiné Urbán Edit - 15.
Antimicrobial resistance
- Zsoldiné Urbán Edit - 16. Immunology of infectious diseases I - Polgár Beáta
- 17. Immunology of infectious diseases II - Polgár Beáta
- 18. Immunology of infectious diseases III - Polgár Beáta
- 19. Immunotherapy I - Polgár Beáta
- 20. Immunotherapy II - Polgár Beáta
- 21.
Vaccinology I
- Balázs Benigna - 22.
Vaccinology II
- Balázs Benigna - 23.
Pyogenic bacteria I - Staphylococci
- Melegh Szilvia Zsóka - 24.
Pyogenic bacteria II - Streptococci
- Melegh Szilvia Zsóka - 25.
Pyogenic bacteria III - Neisseria
- Melegh Szilvia Zsóka - 26. Enteric bacteria and gastrointestinal pathogens I - Tigyi Zoltán
- 27. Enteric bacteria and gastrointestinal pathogens II - Tigyi Zoltán
- 28. Enteric bacteria and gastrointestinal pathogens III - Tigyi Zoltán
Practices
Seminars
Reading material
Obligatory literature
Denyer SP, Hodges NA, Gorman SP, Gilmore BF: Hugo and Russells Pharmaceutical Microbiology, 8th Edition, Blackwell Science Ltd 2018. ISBN: 978-1-119-43449-8
Tim Sandle: Pharmaceutical Microbiology: Essentials for Quality Assurance and Quality Control, ELSEVIER SCIENCE & TECHNOLOGY,Woodhead Publishing Ltd, 2015 ISBN10 0081000227
Literature developed by the Department
Lecture slides on Teams
Notes
Recommended literature
Dr. Patrick R. Murray, Dr. Ken S. Rosenthal and Dr. Michael A. Pfaller (eds.): Medical Microbiology, 8th edition, Elsevier Saunders 2020, ISBN13 (EAN): 9780323673228
F.H. Kayser, K.A. Bienz, J. Eckert, R.M. Zinkernagel: Medical Microbiology, Thieme Stuttgart 2005, ISBN: 3-13-131991-7
Conditions for acceptance of the semester
Students are encouraged to attend lectures, as they facilitate a better understanding of the curriculum.
Mid-term exams
Instructors may verify attendance during lectures through unannounced short quizzes. Attendance points earned during the semester will be added to the exam score in the exam-period as follows:
+3 points: 100% participation in the verified sessions and submission of answers.
+2 points: 85–99% participation in the verified sessions and submission of answers.
+1 point: 75–84% participation in the verified sessions and submission of answers.
Earned attendance points are also valid for retake exams within the same semester. In the event of a course retake in a subsequent academic year (exam-only course), these bonus points cannot be carried over.
Making up for missed classes
-
Exam topics/questions
The written exam consists of 60 single choice questions with 4 possible answers. Final score consists of the exam score and the attendance points. The final score is graded according to a five-grade scale:
54-60 points (90-100%) - excellent (5);
48-53 points (80-89%) - good (4);
42-47 points (70-79%) - average (3);
36-41 points (60-69%) - pass (2);
0-35 points (0-59%) - fail (1).
Examiners
- Balázs Benigna
- Kocsis Béla
- Melegh Szilvia Zsóka
- Nyul Adrienn
- Polgár Beáta
- Tigyi Zoltán
- Zsoldiné Urbán Edit