The Antimicrobial Drugs and their Clinical Use

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

  • Kocsis Béla

    associate professor,
    Department of Medical Microbiology and Immunology

Number of hours/semester

lectures: 24 hours

practices: 0 hours

seminars: 0 hours

total of: 24 hours

Subject data

  • Code of subject: OBF-057-T
  • 2 kredit
  • Biotechnology MSc
  • Optional modul
  • spring
Prerequisites:

-

Course headcount limitations

min. 5 – max. 100

Topic

The aim of these lectures is to give a reliable and detailed knowledge about the antimicrobial drugs and their clinical use; to give ideas how to choose the proper drug for the prophylaxis and therapy of infectious diseases

Lectures

  • 1. Introduction, historical data, basic definitions - Kocsis Béla
  • 2. Characterisation of antimicrobial drugs, chemical structure, their targets - Kocsis Béla
  • 3. Characterisation of antimicrobial drugs, sensitivity and resistance - Kocsis Béla
  • 4. Pharmacokinetics and pharmacodynamics of anti-infective drugs - Kocsis Béla
  • 5. The antibiotic prophylaxis. - Kocsis Béla
  • 6. The empiric antimicrobial therapy - Kocsis Béla
  • 7. The antimicrobial therapy based on microbiologic result - Kocsis Béla
  • 8. The choice of best antimicrobial drug - Kocsis Béla
  • 9. The reasons of an unsuccessful antimicrobial therapy - Kocsis Béla
  • 10. The antimicrobial drugs in details. The inhibitors of the cell wall biosynthesis Beta-lactams Penicillins - Kocsis Béla
  • 11. Cephalosporins, carbapenems, monobactams, glicopeptides - Kocsis Béla
  • 12. The inhibitors of the protein biosynthesis Aminoglicosides - Kocsis Béla
  • 13. Tetracyclines Chloramphenicol Macrolides - Kocsis Béla
  • 14. The inhibitors of the nucleic acid biosynthesis Rifampins Sulfonamides - Kocsis Béla
  • 15. Kinolons Fluorokinolons - Kocsis Béla
  • 16. The antimycotic drugs - Kocsis Béla
  • 17. The antiviral drugs HIV - AIDS - Kocsis Béla
  • 18. The antiparasitic therapy. The chemoprophylaxis of malaria - Kocsis Béla
  • 19. The antimicrobial therapy of respiratory and urinary tract infections - Kocsis Béla
  • 20. Cardiovascular and wound infections, sepsis - Kocsis Béla
  • 21. Central nervous system, abdominal and enteric infections - Kocsis Béla
  • 22. Antimicrobial therapy of patients under immunosuppression, pregnancy.... - Kocsis Béla
  • 23. The pharmacological aspects of antimicrobial therapy - Kocsis Béla
  • 24. The future of antimicrobial therapy - Kocsis Béla

Practices

Seminars

Reading material

Obligatory literature

Jawetz et al.: Medical Microbiology

Literature developed by the Department

Notes

Recommended literature

Conditions for acceptance of the semester

at the end of semester there is an written test: 50 multiple choise questions 52% result

Mid-term exams

In the first 2 weeks of the exam period we give three times possibilities to write tests

Making up for missed classes

None

Exam topics/questions

None

Examiners

Instructor / tutor of practices and seminars